Prenatal stress down-regulates Reelin expression by methylation of its promoter and induces adult behavioral impairments in rats.

Autor: Palacios-García I; Departamento de Psiquiatría, Escuela de Medicina, and Centro Interdisciplinario de Neurociencia, Pontificia Universidad Católica de Chile, Santiago, Chile; Laboratory of Cell and Neuronal Dynamics (Cenedyn), Department of Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile., Lara-Vásquez A; Departamento de Psiquiatría, Escuela de Medicina, and Centro Interdisciplinario de Neurociencia, Pontificia Universidad Católica de Chile, Santiago, Chile., Montiel JF; Centro de Investigación Biomédica, Facultad de Medicina, Universidad Diego Portales, Santiago, Chile., Díaz-Véliz GF; Programa de Farmacología Molecular y Clínica, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile., Sepúlveda H; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, and Fondo de Áreas Prioritarias (FONDAP) 'Center for Genome Regulation', Universidad Andrés Bello, Santiago, Chile., Utreras E; Laboratory of Cell and Neuronal Dynamics (Cenedyn), Department of Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile., Montecino M; Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, and Fondo de Áreas Prioritarias (FONDAP) 'Center for Genome Regulation', Universidad Andrés Bello, Santiago, Chile., González-Billault C; Laboratory of Cell and Neuronal Dynamics (Cenedyn), Department of Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile., Aboitiz F; Departamento de Psiquiatría, Escuela de Medicina, and Centro Interdisciplinario de Neurociencia, Pontificia Universidad Católica de Chile, Santiago, Chile.

Publikováno v: PloS one [PLoS One] 2015 Feb 13; Vol. 10 (2), pp. e0117680. Date of Electronic Publication: 2015 Feb 13 (Print Publication: 2015).