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Autor:
Díaz Martínez, Adolfo, Siro Herrero, Jorge G., García Navío, José Luis, Vaquero López, Juan J., Álvarez-Builla Gómez, Julio
Publikováno v:
e_Buah Biblioteca Digital Universidad de Alcalá
instname
instname
A stereoselective synthesis of (R)-(-)-rolipram from L-glutamic acid is described. The key step is a stereoselective Michael addition of an arylcuprate to a modified pyroglutamic derivative which acts as the template to induce the stereoselectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cd4c04b2dfc6b633f77adb0ac2c5f1be
http://hdl.handle.net/10017/3591
http://hdl.handle.net/10017/3591