Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Dênia Antunes Saúde Guimarães"'
Autor:
Rafaela Cunha Matosinhos, Frédéric Frézard, Sabrina Mendes Silva Araújo, Andressa Magalhães Barbosa, Isabela Fernanda de Souza, José Dias de Souza Filho, Jacqueline de Souza, Ana Paula Corrêa Oliveira Bahia, Francesca Ietta, Agnese Magnani, Dênia Antunes Saúde-Guimarães
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Gout and hyperuricemia are characterized by high uric acid levels, and their treatment involves medications that have adverse effects. In this study, we evaluated oral liposomal formulations with eremantholide C and goyazensolide as a novel
Externí odkaz:
https://doaj.org/article/1ecf2fd4506d473390c62023b6c43528
Autor:
Arthur Ferrari Teixeira, Jacqueline de Souza, Douglas Daniel Dophine, José Dias de Souza Filho, Dênia Antunes Saúde-Guimarães
Publikováno v:
Molecules, Vol 27, Iss 5, p 1506 (2022)
In vivo assays and chemical analyses were performed on the ethanolic extract from leaves of Eruca sativa. UHPLC-ESI-QTOF analysis confirmed the presence of glucosinolates and flavonol glucosides. The major flavonoid of the ethanolic extract, kaempfer
Externí odkaz:
https://doaj.org/article/6fb17cc4908e4e20a293eb0e0011b5e5
Autor:
Renata Tupinambá Branquinho, Gwenaelle Pound-Lana, Matheus Marques Milagre, Dênia Antunes Saúde-Guimarães, José Mário Carneiro Vilela, Margareth Spangler Andrade, Marta de Lana, Vanessa Carla Furtado Mosqueira
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Lychnopholide, a lipophilic sesquiterpene lactone, is efficacious in mice at the acute and chronic phases of Chagas disease. Conventional poly-ε-caprolactone (PCL) and long-circulating poly(D,L-lactide)-block-polyethylene glycol (PLA-PEG) n
Externí odkaz:
https://doaj.org/article/074da5eb82c840749373906e42b4468c
Autor:
Iara Dévula Tiso Tana, Dênia Antunes Saúde-Guimarães, Tamires Guedes Caldeira, Maria Betânia de Freitas Marques, Wagner da Nova Mussel, Jacqueline de Souza
Publikováno v:
Journal of Pharmacy and Pharmacology. 74:1140-1151
Objectives To predict the substance’s behaviour in vivo and determine the viability of the bioactive substance to become a drug, this work aimed to evaluate the biopharmaceutics characteristics of goyazensolide. Methods Differential scanning calori
Autor:
Grazielle Brandão Coelho, Ana Catharina Fernandes Pereira Fer Bernardes, Camila Martins de Sá Müller, Vanessa de Assis Barros Serra, Dênia Antunes Saúde-Guimarães
Publikováno v:
Revista Brasileira de Farmacognosia. 32:386-394
Autor:
Dênia Antunes Saúde-Guimarães, Bruno César de Albuquerque Ugoline, Tamires Guedes Caldeira, Jacqueline de Souza
Publikováno v:
Revista Brasileira de Farmacognosia. 31:453-462
Previous studies have demonstrated the anti-inflammatory and antihyperuricemic activities of dried ethanolic extract of the aerial parts of Lychnophora passerina (Mart ex DC.) Gardner, Asteraceae, and then the potential to become a pharmaceutical pro
Autor:
Jacqueline de Souza, Dênia Antunes Saúde-Guimarães, Marival Bermejo, Tamires Guedes Caldeira, Isabel González-Álvarez
Publikováno v:
Daru
BACKGROUND: Lychnophora trichocarpha (Spreng.) Spreng. ex Sch.Bip has been used in folk medicine to treat pain, inflammation, rheumatism and bruises. Eremantholide C, a sesquiterpene lactone, is one of the substances responsible for the anti-inflamma
Autor:
Arthur Ferrari, Teixeira, Jacqueline, de Souza, Douglas Daniel, Dophine, José Dias, de Souza Filho, Dênia Antunes, Saúde-Guimarães
Publikováno v:
Molecules (Basel, Switzerland). 27(5)
In vivo assays and chemical analyses were performed on the ethanolic extract from leaves of
Autor:
Dênia Antunes Saúde-Guimarães, Camila Helena Barros, Marcela Carolina de Paula Michel Araújo, Rodrigo Dian de Oliveira Aguiar Soares, Daniela Sachs, Grazielle Brandão Coelho, Rafaela Cunha Matosinhos, Juliana Pantaleão Bezerra, Ana Catharina Fernandes Pereira Ferreira Bernardes
Publikováno v:
Journal of ethnopharmacology. 284
Coffea arabica is commonly known for its cardiotonic and neurotonic activities, but in some places' folk medicine, like in Arabia and Africa, C. arabica is used to treat headache, migraine, the flu, anemia, oedema, asthenia, asthma, inflammation and
Autor:
Gmp de Assis, Les Reis, Matheus Marques Milagre, Dênia Antunes Saúde-Guimarães, Marta de Lana, Maykon Tavares de Oliveira, Maira Fonseca Gonçalves, Renata Tupinambá Branquinho
Publikováno v:
Parasitology. 147:108-119
Background:The current drugs for Chagas disease treatment present several limitationsMethods:The sesquiterpene lactone goyazensolide (GZL) was evaluated regarding to cytotoxicity and trypanocidal activity against amastigotes, selectivity index (SI) i