Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Désirée H. Veening-Griffioen"'
Autor:
Guilherme S. Ferreira, Francis M. Dijkstra, Désirée H. Veening-Griffioen, Wouter P. C. Boon, Huub Schellekens, Ellen H. M. Moors, Peter J. K. van Meer, Frederik E. Stuurman, Joop M. A. van Gerven
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The primary purpose of this study was to assess the translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system (CNS) active drugs. As a part of this, IBs were reviewed on re
Externí odkaz:
https://doaj.org/article/969744b409794e0e8e65ec07d7ce391d
Autor:
Bilal Alashkar Alhamwe, Laura A. P. M. Meulenbroek, Désirée H. Veening-Griffioen, Tjalling M. D. Wehkamp, Fahd Alhamdan, Sarah Miethe, Hani Harb, Astrid Hogenkamp, Léon M. J. Knippels, Elke Pogge von Strandmann, Harald Renz, Johan Garssen, Betty C. A. M. van Esch, Holger Garn, Daniel P. Potaczek, Machteld M. Tiemessen
Publikováno v:
Nutrients, Vol 12, Iss 10, p 3193 (2020)
Immunoglobulin E (IgE)-mediated allergy against cow’s milk protein fractions such as whey is one of the most common food-related allergic disorders of early childhood. Histone acetylation is an important epigenetic mechanism, shown to be involved i
Externí odkaz:
https://doaj.org/article/aab0e6eca7c94518a9ae8f2e07d217a0
Autor:
Guilherme S. Ferreira, Désirée H. Veening-Griffioen, Wouter P. C. Boon, Ellen H. M. Moors, Peter J. K. van Meer
Publikováno v:
Animals, Vol 10, Iss 7, p 1199 (2020)
Reports of a reproducibility crisis combined with a high attrition rate in the pharmaceutical industry have put animal research increasingly under scrutiny in the past decade. Many researchers and the general public now question whether there is stil
Externí odkaz:
https://doaj.org/article/786ec96520b24d25bd7663606e9e8672
Autor:
Guilherme S Ferreira, Désirée H Veening-Griffioen, Wouter P C Boon, Ellen H M Moors, Christine C Gispen-de Wied, Huub Schellekens, Peter J K van Meer
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218014 (2019)
IntroductionPoor translation of efficacy data derived from animal models can lead to clinical trials unlikely to benefit patients-or even put them at risk-and is a potential contributor to costly and unnecessary attrition in drug development.Objectiv
Externí odkaz:
https://doaj.org/article/0f14ca084e9b487cb8a1f7e01b4a38f6
Autor:
Guilherme S Ferreira, Désirée H Veening-Griffioen, Wouter P C Boon, Ellen H M Moors, Christine C Gispen-de Wied, Huub Schellekens, Peter J K van Meer
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220325 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0218014.].
Externí odkaz:
https://doaj.org/article/4a9a1b7212f24fd09f77e8357dbb8bd4