A dose-finding clinical trial of staphylokinase SY162 in patients with long-term venous access catheter thrombotic occlusion

Autor: Désiré Collen, M. Stas, Godelieve Goossens, Peter Verhamme, Geert Maleux

Publikováno v: Journal of Thrombosis and Thrombolysis. 24:1-5

We investigated the safety and efficacy of several dosing regimens of catheter-directed staphylokinase (SY162) bolus administration for the treatment of long-term venous access catheter occlusion.This open-label, ascending dose study enrolled 24 subj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4db1d9d4e934ee9606d117bfc76709
https://doi.org/10.1007/s11239-006-0006-4

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

Autor: Ingeborg Stalmans, Yin-Shan Ng, Richard Rohan, Marcus Fruttiger, Ann Bouché, Ali Ÿuce, Hajime Fujisawa, Bart Hermans, Moshe Shani, Sandra Jansen, Dan Hicklin, David J. Anderson, Tom Gardiner, Hans-Peter Hammes, Lieve Moons, Mieke Dewerchin, Désiré Collen, Peter Carmeliet, Patricia A. D’Amore

Publikováno v: Journal of Clinical Investigation. 109:327-336

The murine VEGF gene is alternatively transcribed to yield the VEGF(120), VEGF(164), and VEGF(188) isoforms, which differ in their potential to bind to heparan sulfate and neuropilin-1 and to stimulate endothelial growth. Here, their role in retinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a315c121cfba82c4511ef5982e3417
https://doi.org/10.1172/jci0214362

Circulating Oxidized LDL Is a Useful Marker for Identifying Patients With Coronary Artery Disease

Autor: Raymond Verhaeghe, Frans Van de Werf, Paul Holvoet, Peter Verhamme, Erik Muls, Ann Mertens, Désiré Collen, Kris Bogaerts, G. Beyens

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 21:844-848

Abstract —Our aim was to determine the usefulness of circulating oxidized low density lipoprotein (LDL) in the identification of patients with coronary artery disease (CAD). A total of 304 subjects were studied: 178 patients with angiographically p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390a0672f4d55d94d0e3ff435e2e2a4c
https://doi.org/10.1161/01.atv.21.5.844

Adenovirus-Mediated Transfer of Tissue-Type Plasminogen Activator Augments Thrombolysis in Tissue-Type Plasminogen Activator–Deficient and Plasminogen Activator Inhibitor-1–Overexpressing Mice

Autor: Jean Marie Stassen, Robert S. Meidell, Robert D. Gerard, Désiré Collen, Ilse Van Vlaenderen, Peter Carmeliet

Publikováno v: Blood. 90:1527-1534

Impaired fibrinolysis, resulting from increased plasminogen activator inhibitor-1 (PAI-1) or reduced tissue-type plasminogen activator (t-PA) plasma levels, may predispose the individual to subacute thrombosis in sepsis and inflammation. The objectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f0b279eada46adc1f07960958a82ecf
https://doi.org/10.1182/blood.v90.4.1527

Title Page / Table of Contents, Vol. 26, Supplement 4, 1996

Autor: I. Elalamy, Sanne Valentin, J.P. Vannier, Martine Renard, Theo Lindhout, C. Soria, Harlan F. Weisman, Bengt Zöller, A.M.H.P. van.den.Besselaar, A. Pruvost, M. Trossaërt, Kalid Azzam, Michel René Boisseau, J. Paysant, Désiré Collen, Andreas Hillarp, M. Martínez, Amparo Vaya, Amparo Vayá, A. Maurel, Barry S. Coller, Ferruccio Berti, Chiara Cerletti, Keaven M. Anderson, J. Conard, Ludovic Drouet, M. Renard, Annie Pruvost, Alexander G.G. Turpie, R.R. Forastiero, A. Del Maschio, Michel Bonneau, J. Dalmau, Francis Belloc, Irene Lluch, G. van Willigen, D. Simon, Helen Ireland, J.W.N. Akkerman, Giovannni de Gaetano, Irene Salemink, M. Verstraete, N. Resnick-Roguel, Reiner Muller-Peddinghaus, Claire Bal dit Sollier, Patrick Andre, Justo Aznar, Alan T. Nurden, M. Pick, M. Vasse, C. Closse, Margareta Hellgren, James H. Chesebro, Lorenzo Gil, Björn Dahlbäck, A. Panet, David A. Lane, Sophie Gandrille, L.O. Carreras, Marcial Martínez, Marie-Claire Boffa, Norma B de Bosch, G. Kunz, Yale Nemerson, M. Korner, M.H. Horellou, Per Morten Sandset, John T. Fallon, David Bergqvist, Rafael Carmena, Patrice Dumain, D. Sela-Donenfeld, M.R. Boisseau, Roberto Marti, Pier Mannuccio Mannucci, J.P. Collet, Angelo Sala, L. Poller, E. Dejana, M. Seigneur, Valentin Fuster, A. Zanetti, Frans Van de Werf, Douglas A. Triplett, Joan E.B. Fox, Armando Tripodi, Christèle Closse, Virgilio Evangelista, Martine Aiach, F. Belloc, M.M. Samama, Rafael Apitz, J. Soria, J. Hirsh, B. Boneu, Giancarlo Folco, Jacques Maclouf, Virgilio Bosch, George M. Willems, Peter Carmeliet, Patricia Hainaud, Giuseppe Rossoni, Konstantinos Kyriakoulis, M. Labios, Steven Vanderschueren, George Pignaud, A. Eldor, JuanJose Badimon, Martine Seigneur

Publikováno v: Pathophysiology of Haemostasis and Thrombosis. 26:I-VII

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ef37e2b78736eb835bde9699c8a6064
https://doi.org/10.1159/000217281