Výsledky vyhledávání - "Déborah Hirt"

Akademický článek

Frequencies, Modalities, Doses and Duration of Computerized Prescriptions for Sedative, Analgesic, Anesthetic and Paralytic Drugs in Neonates Requiring Intensive Care: A Prospective Pharmacoepidemiologic Cohort Study in 30 French NICUs From 2014 to 2020

Autor: Manon Tauzin, Béatrice Gouyon, Déborah Hirt, Ricardo Carbajal, Jean-Bernard Gouyon, Anne-Claire Brunet, Matthieu Ortala, Seydou Goro, Camille Jung, Xavier Durrmeyer

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Objectives: No consensus exists about the doses of analgesics, sedatives, anesthetics, and paralytics used in critically ill neonates. Large-scale, detailed pharmacoepidemiologic studies of prescription practices are a prerequisite to future research

Externí odkaz: https://doaj.org/article/9bc3bb945d854937a7fe0026998d353d

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Population pharmacokinetics of cefazolin in critically ill children infected with methicillin-sensitive Staphylococcus aureus

Autor: Julie Toubiana, Jean-Marc Tréluyer, Sihem Benaboud, E. Bille, Saik Urien, Florence Moulin, Guillaume Geslain, Mehdi Oualha, E. Salvador, Yi Zheng, Inès Gana, C. Briand, Olivier Bustarret, Déborah Hirt, S. Renolleau, S. Boujaafar, Agathe Béranger

Publikováno v: Clinical Microbiology and Infection. 27:413-419

Objectives Cefazolin is one of curative treatments for infections due to methicillin-sensitive Staphylococcus aureus (MSSA). Both growth and critical illness may impact the pharmacokinetic (PK) parameters. We aimed to build a population PK model for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07fe52e84713a846308e58ef7c24f8e
https://doi.org/10.1016/j.cmi.2020.04.022

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Dosing Recommendations for Lamotrigine in Children: Evaluation Based on Previous and New Population Pharmacokinetic Models

Autor: Radia Aboura, Naïm Bouazza, Inès Gana, Jean-Marc Tréluyer, Isabelle Desguerre, Camille Chenevier-Gobeaux, Yi Zheng, Rima Nabbout, Déborah Hirt, Manon Tauzin, Sihem Benaboud, Cécile Freihuber, Thierry Billette de Villemeur

Publikováno v: The Journal of Clinical Pharmacology. 61:677-687

Lamotrigine is a broad-spectrum antiepileptic drug with high interindividual variability in serum concentrations in children. The aims of this study were to evaluate the predictive performance of pediatric population pharmacokinetic (PPK) models publ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4accbe9973611d2b0e640ecda786b5f4
https://doi.org/10.1002/jcph.1791

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Comparison of three galenic forms of lamivudine in young West African children living with Human Immunodeficiency Virus

Autor: Saik Urien, Caroline Yonaba, Jean-Marc Tréluyer, Alain Pruvost, Sophie Desmonde, Désiré Lucien Dahourou, Frantz Foissac, Evelyne Dainguy, Karen Malateste, Claire Pressiat, Déborah Hirt, Valériane Leroy, Naïm Bouazza, François Tanoh Eboua

Publikováno v: Antiviral therapy. 26(6-8)

Background Few pharmacokinetic data were reported on dispersible tablets despite their increasing use. One hundred fifty HIV-infected children receiving lamivudine were enrolled in the MONOD ANRS 12,206 trial. Three galenic forms were administered: l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f387c9ce010600f81a8a9e2c21bbbc6
https://pubmed.ncbi.nlm.nih.gov/35485334

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Maternal Betamethasone for Prevention of Respiratory Distress Syndrome in Neonates: Population Pharmacokinetic and Pharmacodynamic Approach

Autor: Frantz Foissac, Yves Ville, Patrick Rozenberg, Sihem Benaboud, Déborah Hirt, Yi Zheng, Gabrielle Lui, Laurent Mandelbrot, Naïm Bouazza, Jean-Marc Tréluyer, Pierre-Henri Jarreau, Gilles Kayem, François Goffinet

Publikováno v: Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2020, 108 (5), pp.1026-1035. ⟨10.1002/cpt.1887⟩

International audience; Despite antenatal corticosteroids therapy, respiratory distress syndrome (RDS) is still a leading cause of neonatal morbidity and mortality in premature newborns. To date, the relationship between in utero fetal drug exposure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d8d0436a07058709a17323764a2d46
https://doi.org/10.1002/cpt.1887

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Cefepime population pharmacokinetics and dosing regimen optimization in critically ill children with different renal function

Autor: Noémie de Cacqueray, Déborah Hirt, Yi Zheng, Emmanuelle Bille, Pierre Louis Leger, Jérôme Rambaud, Julie Toubiana, Anais Chosidow, Sophie Vimont, Delphine Callot, Laurent Chouchana, Agathe Béranger, Jean Marc Tréluyer, Sihem Benaboud, Mehdi Oualha

Publikováno v: Clinical Microbiology and Infection. 28:1389.e1-1389.e7

Cefepime is commonly used in pediatric intensive care units, where unpredictable variations in the patients' pharmacokinetic (PK) variables may require drug dose adjustments. The objectives of the present study were to build a population PK model for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2fa500a895d4d7f6f142761d3fa785
https://doi.org/10.1016/j.cmi.2022.05.007

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Efficacy and safety of subcutaneous administration of ceftazidime as a salvage therapy in geriatrics: a case report

Autor: Elsa Salomon, Déborah Hirt, Benjamin Davido, Jean-Claude Alvarez, Hugues Michelon, Aurélien Dinh, Jean-Laurent Le Quintrec, Marie Tardivel

Publikováno v: Fundamental & Clinical Pharmacology. 34:521-524

Ceftazidime is a third-generation cephalosporin used for the treatment of Gram-negative bacteria only approved for parenteral use by intravenous and intramuscular route. In some clinical situations, off-label subcutaneous injection could be a salvage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a2bfd578385113c743e2dfed733bc9e
https://doi.org/10.1111/fcp.12520

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Population pharmacokinetics of meropenem in critically ill children with different renal functions

Autor: Mehdi Oualha, Naïm Bouazza, Sihem Benaboud, Frantz Foissac, Florence Moulin, Jean-Marc Tréluyer, Emmanuelle Bille, Inès Gana, Sylvain Renolleau, Agathe Béranger, Saik Urien, Yi Zheng, Fabrice Lesage, Déborah Hirt, Mélanie Rapp

Publikováno v: European Journal of Clinical Pharmacology. 76:61-71

We aimed to develop a meropenem population pharmacokinetic (PK) model in critically ill children and simulate dosing regimens in order to optimize patient exposure. Meropenem plasma concentration was quantified by high-performance liquid chromatograp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7eb3ebd1ad00f282f25e07a015c1d84
https://doi.org/10.1007/s00228-019-02761-7

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