Výsledky vyhledávání - "Déborah Crombez"

Modulation of adiponectin receptors AdipoR1 and AdipoR2 by phage display-derived peptides in in vitro and in vivo models

Autor: Luce Vander Elst, Déborah Crombez, Miriam Cnop, Sophie Laurent, Carmen Burtea, Denis Nonclercq, Robert N. Muller, Sébastien Delcambre

Publikováno v: Journal of drug targeting

Type 2 diabetes (T2D) is often linked to metabolic syndrome, which assembles various risk factors related to obesity. Plasma levels of adiponectin are decreased in T2D and obese subjects. Aiming to develop a peptide able to bind adiponectin receptors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48469c4bf45bc6609b0e8375085fbbe0
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/303264

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Carboxy-silane coated iron oxide nanoparticles: a convenient platform for cellular and small animal imaging

Autor: Ludivine Wacheul, Sophie Laurent, Dimitri Stanicki, Sébastien Boutry, Emilien Nicolas, Déborah Crombez, Denis L. J. Lafontaine, Robert N. Muller, Luce Vander Elst

Publikováno v: Journal of materials chemistry. B. 2(4)

This study reports the synthesis of stabilized ultrasmall iron oxide nanoparticles (USPIO) as bimodal probes for magnetic resonance and optical imaging. These nanosystems are based on small iron oxide cores surrounded by a thin polysiloxane shell exh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb5520cab3d5a7932dfb6eab22b842c
https://pubmed.ncbi.nlm.nih.gov/32261383

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Development of a peptide-functionalized imaging nanoprobe for the targeting of (FXYD2)γa as a highly specific biomarker of pancreatic beta cells

Autor: Decio L. Eizirik, Corine Sermeus, Isabelle Salmon, Sophie Laurent, Daisy Flamez, Déborah Crombez, Carmen Burtea, Isabelle Millard, Sandrine Rorive, Luce Vander Elst, Marie-Claire Beckers, Sébastien Delcambre, Robert N. Muller

Publikováno v: Contrast Media & Molecular Imaging. 10:398-412

Diabetes is characterized by a progressive decline of the pancreatic beta cell mass (BCM), which is responsible for insufficient insulin secretion and hyperglycaemia. There are currently no reliable methods to measure non-invasively the BCM in diabet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0efc7fb44245d42dda373670f3ec548f
https://doi.org/10.1002/cmmi.1641

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Potential therapeutic peptides targeted to adiponectin receptors, able to modulate the AMPK pathway and regulate the glucose and lipid metabolism

Autor: Robert N. Muller, Déborah Crombez, Carmen Burtea

Publikováno v: Diabetologie und Stoffwechsel. 11

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca523b5175b34736e55c5a021e8cd66d
https://doi.org/10.1055/s-0036-1580805

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In vitro and in vivo characterization of several functionalized ultrasmall particles of iron oxide, vectorized against amyloid plaques and potentially able to cross the blood-brain barrier: toward earlier diagnosis of Alzheimer's disease by molecular imaging

Autor: Sophie Laurent, Luce Vander Elst, Déborah Crombez, Denis Nonclercq, Robert N. Muller, Carmen Burtea, Emilie Ansciaux

Publikováno v: Contrast mediamolecular imaging. 10(3)

Alzheimer's disease (AD) is a neurodegenerative disorder most often diagnosed 10 years after its onset and development. It is characterized by the accumulation of amyloid-β peptide (ABP) into amyloid plaques between nerve cells, which produces a mas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5a7337570be1f9e9a1a24442ee6596
https://pubmed.ncbi.nlm.nih.gov/25284012

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