In vivo chemotherapeutic insight of a novel isocoumarin (3-hexyl-5,7-dimethoxy-isochromen-1-one): Genotoxicity, cell death induction, leukometry and phagocytic evaluation

Autor: Débora Rojas de Figueiredo, João Renato Pesarini, Sarah Alves Auharek, Alisson Meza, Dênis Pires de Lima, Adilson Beatriz, Roberto da Silva Gomes, Rodrigo Juliano Oliveira, Andréia Conceição Milan Brochado Antoniolli-Silva, Flávio Henrique Souza de Araújo, Candida Aparecida Leite Kassuya, Antônio Carlos Duenhas Monreal

Publikováno v: Genetics and Molecular Biology, Volume: 40, Issue: 3, Pages: 665-675, Published: SEP 2017
Genetics and Molecular Biology
Genetics and Molecular Biology v.40 n.3 2017
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Vol 40, Iss 3, Pp 665-675

Chemotherapy is one of the major approaches for the treatment of cancer. Therefore, the development of new chemotherapy drugs is an important aspect of medicinal chemistry. Chemotherapeutic agents include isocoumarins, which are privileged structures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336cf0eda68eba33185a45dcd34af05b
https://doi.org/10.1590/1678-4685-gmb-2016-0316