Synthesis, Characterization, and Activity of Hydroxymethylnitrofurazone Nanocrystals against Trypanosoma cruzi and Leishmania spp

Autor: Cauê Scarim, Aline de Souza, Débora Marins, Elda Santos, Lívia de Figueiredo Diniz Castro, Ivo Caldas, Patrícia Espuri, Marcos Marques, Elizabeth Ferreira, Nadia Bou-Chacra, Chung Chin

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Drugs and Drug Candidates; Volume 1; Issue 1; Pages: 43-55

Hydroxymethylnitrofurazone (NFOH) is a prodrug of nitrofurazone devoid of mutagenic toxicity, with in vitro and in vivo activity against Trypanosoma cruzi (T. cruzi) and in vitro activity against Leishmania. In this study, we aimed to increase the so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12f4471e4614c7add59e2860d1d9942