Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Débora Gisele, Salomón"'
Autor:
Alejandro Carlos Curino, Norberto Ariel Gandini, Maria Marta Facchinetti, Yagamare Fall, Marcos L. Rivadulla, Generosa Gómez, Alejandro López Romero, María Eugenia Fermento, María Julia Ferronato, Débora Gisele Salomón, Manuel Pérez, Xenxo Pérez-García
Publikováno v:
Archiv der Pharmazie. 348:315-329
The active form of vitamin D3, 1α,25(OH)2D3, plays a major role in maintaining calcium/phosphate homeostasis. In addition, it is a potent antiproliferative and pro-differentiating agent. Unfortunately, it usually causes hypercalcemia in vivo when ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4870222a27f2e501ec038bf7df0be06
https://doi.org/10.1002/ardp.201400448
https://doi.org/10.1002/ardp.201400448
Autor:
Evangelina Mascaró, Alejandro Carlos Curino, Norberto Ariel Gandini, Eliana Noelia Alonso, Cristian Vitale, María Julia Ferronato, Maria Marta Facchinetti, Yagamare Fall, María Eugenia Fermento, Débora Gisele Salomón, Mario Alfredo Quevedo
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 178
Glioblastoma multiforme (GBM) is the worst and most common brain tumor, characterized by high proliferation and invasion rates. The current standard treatment is mainly based on chemoradiotherapy and this approach has slightly improved patient surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f0dab7dbfe3d7475ae9af1d86f93b8
https://pubmed.ncbi.nlm.nih.gov/29102624
https://pubmed.ncbi.nlm.nih.gov/29102624
Autor:
María Julia Ferronato, Alejandro Carlos Curino, Débora Gisele Salomón, Evangelina Mascaro, Gabriel Radivoy, Silvina Mariela Grioli, Maria Marta Facchinetti, Cristian Vitale
Publikováno v:
Current Topics in Medicinal Chemistry. 14:2408-2423
The active metabolite of vitamin D, 1α, 25 dihydroxyvitamin D 3 (calcitriol) is classically known to regulate calcium and phosphate homeostasis and bone mineralization. In addition, calcitriol has also been documented to act as a potent anticancer a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cd20aaa82b5d0b54bb025a1667a8be1
https://doi.org/10.2174/1568026615666141208101418
https://doi.org/10.2174/1568026615666141208101418
Autor:
Maria Marta Facchinetti, María Eugenia Fermento, Jean C. Zenklusen, Débora Gisele Salomón, Norberto Ariel Gandini, María Julia Ferronato, Julián Arévalo, Jorge Alejandro Blasco, Alejandro Carlos Curino, Nancy Carolina Andrés
Publikováno v:
Journal of Neuro-Oncology. 118:49-60
Vitamin D and its analogs have been shown to display anti-proliferative effects in a wide variety of cancer types including glioblastoma multiforme (GBM). These anticancer effects are mediated by its active metabolite, 1α, 25-dihydroxyvitamin D3 (ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa2a80ed560894f76b231be9fbf4dd1
https://doi.org/10.1007/s11060-014-1416-3
https://doi.org/10.1007/s11060-014-1416-3
Autor:
Débora Gisele Salomón, Evangelina Mascaró, María Eugenia Fermento, Alejandro Carlos Curino, María Julia Ferronato, Cristian Vitale, Norberto Ariel Gandini, Maria Marta Facchinetti, Eliana Noelia Alonso, Yagamare Fall, Ana Rosa Raimondi, Diego Javier Obiol
The active form of vitamin D3, calcitriol, plays a major role in maintaining calcium/phosphate homeostasis. In addition, it is a potent antiproliferative and prodifferentiating agent. However, when effective antitumor doses of calcitriol are employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79de57c8e660be0211110690df43baa4
Autor:
María Julia, Ferronato, Débora Gisele, Salomón, María Eugenia, Fermento, Norberto Ariel, Gandini, Alejandro, López Romero, Marcos Lois, Rivadulla, Xenxo, Pérez-García, Generosa, Gómez, Manuel, Pérez, Yagamare, Fall, María Marta, Facchinetti, Alejandro Carlos, Curino
Publikováno v:
Archiv der Pharmazie. 348(5)
The active form of vitamin D3, 1α,25(OH)2D3, plays a major role in maintaining calcium/phosphate homeostasis. In addition, it is a potent antiproliferative and pro-differentiating agent. Unfortunately, it usually causes hypercalcemia in vivo when ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e55e54c834a6a006dcbc2870ba58de64
https://pubmed.ncbi.nlm.nih.gov/25864390
https://pubmed.ncbi.nlm.nih.gov/25864390
Autor:
María Eugenia Fermento, Norberto Ariel Gandini, Débora Gisele Salomón, Alejandro Carlos Curino, Myriam Nuñez, Alejandro López Romero, Maria Marta Facchinetti, Manfred Jung, Cristian Vitale, María Julia Ferronato, Julián Arévalo
There is evidence that p300, a transcriptional co-factor and a lysine acetyl-transferase, could play a role both as an oncoprotein and as a tumor suppressor, although little is known regarding its role in breast cancer (BC). First we investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64450f2b568f3bf649ba7b1b8f9adf2a
http://www.ncbi.nlm.nih.gov/pubmed/25240203
http://www.ncbi.nlm.nih.gov/pubmed/25240203
Autor:
Norberto Ariel Gandini, María Eugenia Fermento, Jean C. Zenklusen, Julián Arévalo, Débora Gisele Salomón, Jorge Alejandro Blasco, Alejandro López Romero, Maria Marta Facchinetti, Alejandro Carlos Curino, Diego Javier Obiol, Nancy Carolina Andrés
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
In human glioma tumors, heme oxygenase-1 (HO-1) has been shown to be upregulated both when compared with normal brain tissues and also during oligodendroglioma progression. The cell types that express HO-1 have been shown to be mainly macrophages/mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c978e31ef359a454859b99a701a5c3f5
http://link.springer.com/article/10.1007/s13277-013-1373-z
http://link.springer.com/article/10.1007/s13277-013-1373-z
Autor:
Manuel Pérez, Yagamare Fall, Zoila Gándara, Generosa Gómez, Maria Marta Facchinetti, María Eugenia Fermento, Alejandro Carlos Curino, María Julia Ferronato, Débora Gisele Salomón
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(19)
A new vitamin D2 analogue was synthesized using the Julia-Kocienski olefination. It has antiproliferative effects on cell lines from squamous cell carcinomas of colon and head and neck, but is also as hypercalcaemic as calcitriol in vivo Fil: Gándar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cd0adb165f47119a0085ddb77ad24e
https://pubmed.ncbi.nlm.nih.gov/22926068
https://pubmed.ncbi.nlm.nih.gov/22926068
Autor:
J. Silvio Gutkind, Vyomesh Patel, Maria Marta Facchinetti, Norberto Ariel Gandini, Alejandro Carlos Curino, Débora Gisele Salomón, Jorge Alejandro Blasco, María Eugenia Fermento, Alfredo A. Molinolo
Publikováno v:
Experimental and molecular pathology. 93(2)
The expression of heme oxygenase-1 (HO-1) was shown to be increased in multiple tumors compared with their surrounding healthy tissues and was also observed to be up-regulated in oral squamous cell carcinomas (OSCC). However, conflicting results were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26aa97ffb21e7ae971badaf0213ac41
https://pubmed.ncbi.nlm.nih.gov/22580187
https://pubmed.ncbi.nlm.nih.gov/22580187