Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Débora Foguel"'
Autor:
Márcia Waddington Cruz, Marcus Vinicius Pinto, Luiz Felipe Pinto, Renata Gervais, Moisés Dias, Carlos Perez, Rajiv Mundayat, Moh-Lim Ong, Roberto Coury Pedrosa, Débora Foguel
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 77, Iss 2, Pp 96-100
ABSTRACT Transthyretin amyloidosis (ATTR) is characterized by the deposit of mutant or wild-type transthyretin that forms amyloid fibrils, which are extracellularly deposited within tissues and organs. Clinical manifestations of familial amyloid poly
Externí odkaz:
https://doaj.org/article/3cad4dfa144444e488dbf76795a0c821
Autor:
Júlia T. Oliveira, Vanja Dakic, Gabriela Vitória, Carolina da S.G. Pedrosa, Mayara Mendes, Luiz Guilherme H.S. Aragão, Thyago R. Cardim-Pires, Damien Lelièvre, Daniel Rodrigues Furtado, Roberta O. Pinheiro, Débora Foguel, Lionel Breton, Charbel Bouez, Rodrigo De Vecchi, Marília Zaluar P. Guimarães, Stevens Rehen
Publikováno v:
Neurobiology of Aging. 113:108-117
Aged and photoaged skin exhibit fine wrinkles that are signs of epidermal inflammation and degeneration. It has been shown that healthy elderly skin expresses amyloidogenic proteins, including α-Synuclein, which are known to oligomerize and trigger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47f6bd492c1d0eff9bd8b9a0d632273
https://doi.org/10.1016/j.neurobiolaging.2022.02.010
https://doi.org/10.1016/j.neurobiolaging.2022.02.010
Autor:
Júlia T. Oliveira, Rodrigo De Vecchi, Vanja Dakic, Gabriela Vitória, Carolina Pedrosa, Mayara Mendes, Luiz Guilherme H.S. Aragão, Thyago R. Cardim-Pires, Daniel Rodrigues Furtado, Roberta O. Pinheiro, Débora Foguel, Lionel Breton, Charbel Bouez, Marilia Zaluar P. Guimarães, Stevens Rehen
Cell senescence may promote epidermal inflammation and degeneration, termed as inflammaging, which is accompanied by keratinocyte loss, resulting in fine lines of wrinkles. Recent findings showed that healthy elderly skin expresses age- and neuron-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2875f4c146187189892cc0a65a6aa5e
https://doi.org/10.1101/2021.06.17.448863
https://doi.org/10.1101/2021.06.17.448863
Autor:
Jade Percassi, Vanessa Moreira Sigolo, Pedro Fiori Arantes, Maurício Moura, Debora Foguel, Soraya Soubhi Smaili, Ademar Arthur Chioro dos Reis
Publikováno v:
Revista Eco-Pós, Vol 27, Iss 1 (2024)
O artigo analisa resultados de pesquisas sobre percepção pública sobre o papel das universidades públicas brasileiras no enfrentamento da pandemia de Covid-19. Diante de um contexto de crise sanitária e social, marcado por um governo que assumiu
Externí odkaz:
https://doaj.org/article/481e49ef77ae4c36a5e6524f159695e6
Autor:
Ricardo Sant’Anna, Bruno K. Robbs, Júlia Araújo de Freitas, Patrícia Pires dos Santos, Annekatrin König, Tiago Fleming Outeiro, Debora Foguel
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-16 (2023)
Abstract Background Soluble oligomeric forms of alpha-synuclein (aSyn-O) are believed to be one of the main toxic species in Parkinson’s disease (PD) leading to degeneration. aSyn-O can induce Ca2+ influx, over activating downstream pathways leadin
Externí odkaz:
https://doaj.org/article/026c500fe8464bafaf7b7a9e26e9c403
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1746-1758 (2023)
The aggregation of epitopes that are also able to bind major histocompatibility complex (MHC) alleles raises questions around the potential connection between the formation of epitope aggregates and their affinities to MHC receptors. We first perform
Externí odkaz:
https://doaj.org/article/12ab90bc30de4dd7a556312b97a7e9ea
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Fungal infection is an important health problem in Latin America, and in Brazil in particular. Paracoccidioides (mainly P. brasiliensis and P. lutzii) is responsible for paracoccidioidomycosis, a disease that affects mainly the lungs. The gl
Externí odkaz:
https://doaj.org/article/27f22683f90c4c678bb4cf5fcc951b93
Autor:
Sebastián A, Romano, Yraima, Cordeiro, Luis Maurício T R, Lima, Marilene H, Lopes, Jerson L, Silva, Débora, Foguel, Rafael, Linden
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23(12)
The glycosylphosphatidylinositol (GPI)-anchored prion protein (PrP(C)), usually associated with neurodegenerative diseases, modulates various cellular responses and may scaffold multiprotein cell surface signaling complexes. Engagement of PrP(C) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68a8f2afb58aee7ec5e6c34883d489d6
https://pubmed.ncbi.nlm.nih.gov/19703931
https://pubmed.ncbi.nlm.nih.gov/19703931
Autor:
Juliana dos Santos Oliveira, Dahienne Ferreira Oliveira, Victor Alejandro Essus, Gabriel Henrique Pereira Nunes, Leandro Honorato, José Mauro Peralta, Leonardo Nimrichter, Allan Jefferson Guimarães, Debora Foguel, Alessandra Almeida Filardy, Juliana R. Cortines
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Many aspects of giant viruses biology still eludes scientists, with viruses such as Acanthamoeba polyphaga mimivirus (APMV) and Tupanvirus (TPV) possessing large virions covered by fibrils and are cultivated in laboratories using Acanthamoeba cells a
Externí odkaz:
https://doaj.org/article/527279510d6e46be9e29c1863ff07ef2
Autor:
Renato Domingues, Ricardo Sant’Anna, Anna Carolina Carvalho da Fonseca, Bruno K. Robbs, Debora Foguel, Tiago F. Outeiro
Publikováno v:
Neurobiology of Disease, Vol 168, Iss , Pp 105696- (2022)
Synucleinopathies are a group of progressive neurodegenerative diseases known for the accumulation of insoluble aggregates containing the protein alpha-synuclein (aSyn). Recently, it has been assumed that pathology spreads in the brain during disease
Externí odkaz:
https://doaj.org/article/3537d0bae2444e04bf6516ba6022fca8