Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dávid Czégé"'
Publikováno v:
Experimental Neurology. 219:136-145
Systemic administration of the potassium channel blocker 4-aminopyridine (4-AP) elicits acute convulsions. Synchronized tonic–clonic activity develops during the first hour after the treatment. However, subsequent chronic spontaneous seizures do no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662128cef310abc705764853aca7cb2e
https://doi.org/10.1016/j.expneurol.2009.05.005
https://doi.org/10.1016/j.expneurol.2009.05.005
Publikováno v:
Subcellular Biochemistry 76: “Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)”, Caroline Fonta & László Négyessy (eds)
Subcellular Biochemistry 76: “Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)”, Caroline Fonta & László Négyessy (eds), pp.239-281, 2015, ⟨10.1007/978-94-017-7197-9_12⟩
Subcellular Biochemistry ISBN: 9789401771962
Subcellular Biochemistry 76: “Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)”, Caroline Fonta & László Négyessy (eds), pp.239-281, 2015, ⟨10.1007/978-94-017-7197-9_12⟩
Subcellular Biochemistry ISBN: 9789401771962
Tissue non-specific alkaline phosphatase (TNAP) may be involved in the synthesis of GABA and adenosine, which are the main inhibitory neurotransmitters in cortex. We explored this putative TNAP function through electrophysiological recording (local f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525082a3767f8112d1a340308db5540c
https://hal.archives-ouvertes.fr/hal-02365197
https://hal.archives-ouvertes.fr/hal-02365197
Publikováno v:
Neurotoxicity research. 27(4)
Entorhinal cortex is a highly epilepsy-prone brain region. Effects of repetitive seizures on ionotropic glutamate receptors (iGluRs) were investigated in rat entorhinal cortex slices. Seizures were induced by daily administration of 4-aminopyridine (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3b4268be76c17e3d7cd14e02d37a8c
https://pubmed.ncbi.nlm.nih.gov/25576253
https://pubmed.ncbi.nlm.nih.gov/25576253
Autor:
E. Dobó, Sándor Borbély, B. Szűcs, András Mihály, Anna Vincze, Ildikó Világi, Mónika Bakos, Dávid Czégé, Elek Molnár
Publikováno v:
Neuroscience. 159(1)
The seizure-induced molecular and functional al- terations of glutamatergic transmission in the hippocampus have been investigated. Daily repeated epileptic seizures were induced for 12 days by intraperitoneal administration of 4-aminopyridine (4-AP;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de659e08ee6cf2bb294818847af36d1f
https://pubmed.ncbi.nlm.nih.gov/19154779
https://pubmed.ncbi.nlm.nih.gov/19154779
Publikováno v:
Cell. (3):724-733
SummaryIn CFTR, the chloride ion channel mutated in cystic fibrosis (CF) patients, pore opening is coupled to ATP-binding-induced dimerization of two cytosolic nucleotide binding domains (NBDs) and closure to dimer disruption following ATP hydrolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a4e742e8371a0bceebabd8275359df
Publikováno v:
Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP); 2015, p239-281, 43p
Publikováno v:
Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP); 2015, pi-xxii, 22p
Autor:
Caroline Fonta, László Négyessy
Phosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and the lack of