Semi-Mechanistic Pharmacokinetic Model to Guide the Dose Selection of Nimotuzumab in Patients with Autosomal Dominant Polycystic Kidney Disease.

Autor: Castro-Suárez N; Pharmacy Department, Institute of Food and Pharmacy, University of Havana,Havana 11300, Cuba., Trame MN; AVROBIO Inc., Department of Translational Data Sciences and Advanced Analytics, Cambridge, MA 02139, USA., Ramos-Suzarte M; Center of Molecular Immunology (CIM), Havana 11300, Cuba., Dávalos JM; National Institute of Nephrology (INEF), Havana 10400, Cuba., Bacallao-Mendez RA; National Institute of Nephrology (INEF), Havana 10400, Cuba., Maceo-Sinabele AR; National Center Coordinating of Clinical Trials (CENCEC), Havana 11300, Cuba., Mangas-Sanjuán V; Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Valencia 46100, Spain.; Interuniversity Research Institute for Molecular Recognition and Technological Development, Polytechnic University of Valencia, University of Valencia, Valencia 46100, Spain., Reynaldo-Fernández G; Pharmacy Department, Institute of Food and Pharmacy, University of Havana,Havana 11300, Cuba., Rodríguez-Vera L; Pharmacy Department, Institute of Food and Pharmacy, University of Havana,Havana 11300, Cuba.

Publikováno v: Pharmaceutics [Pharmaceutics] 2020 Nov 26; Vol. 12 (12). Date of Electronic Publication: 2020 Nov 26.