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pro vyhledávání: '"Dániel Szili"'
Autor:
Dániel Szili, Zsuzsanna Bankó, Eszter Angéla Tóth, György Nagy, Bernadette Rojkovich, Tamás Gáti, Melinda Simon, Zoltán Hérincs, Gabriella Sármay
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96381 (2014)
B cell development and activation are regulated by combined signals mediated by the B cell receptor (BCR), receptors for the B-cell activating factor of the tumor necrosis factor family (BAFF-R) and the innate receptor, Toll-like receptor 9 (TLR9). H
Externí odkaz:
https://doaj.org/article/08d557ab011940f2927afc06b9a6f5d5
Publikováno v:
European Journal of Immunology. 44:887-893
The importance of the BCR and TLR9 in autoimmunity and in the production of auto-antibodies is well established but the underlying molecular mechanism still needs to be determined. Here, we aim to characterize the BCR-TLR9 cross-talk by its effect on
Autor:
Tamás Gáti, Mária Tóth, Zsuzsanna Bankó, Dániel Szili, Bernadette Rojkovich, György Nagy, Judit Pozsgay, Gabriella Sármay
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(4)
The most important feature of B cells is the production of Abs upon activation; additionally, B cells produce pro- and anti-inflammatory cytokines in response to certain stimuli. IL-10–producing B cells represent a major subset of regulatory B cell
Publikováno v:
Microbial Ecology. 64:702-713
While oyster mushroom (Pleurotus spp.) is one of the most popular cultivated edible mushrooms, there is scanty information about the microbial community taking part in mushroom substrate production. In this study, an improved sequence-aided terminal
Publikováno v:
Immunology Letters. 143:77-84
The death receptor, CD95/Fas, serves to eliminate potentially dangerous, self-reactive B cells. Engagement of B-cell receptors (BCR) on mature B-cells mediates the escape from cell death resulting in the activation and expansion of antigen specific c
Autor:
Melinda Simon, Dániel Szili, Gabriella Sármay, Zoltán Hérincs, Tamás Gáti, György Nagy, Eszter Angéla Tóth, Bernadette Rojkovich, Zsuzsanna Bankó
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e96381 (2014)
PLoS ONE, Vol 9, Iss 5, p e96381 (2014)
B cell development and activation are regulated by combined signals mediated by the B cell receptor (BCR), receptors for the B-cell activating factor of the tumor necrosis factor family (BAFF-R) and the innate receptor, Toll-like receptor 9 (TLR9). H
Autor:
Dániel Szili, Marcell Cserhalmi, György Nagy, Zsuzsanna Bankó, Gabriella Sármay, David E Szymkowski
Publikováno v:
MABS-AUSTIN MABS.
The Fc receptor (FcgammaRIIb) inhibits B cell responses when coengaged with B cell receptor (BCR), and has become a target for new autoimmune disease therapeutics. For example, BCR and FcgammaRIIb coengagement via the Fc-engineered anti-CD19 XmAb5871
Autor:
György Nagy, Zsuzsanna Bankó, Gabriella Sármay, Marcell Cserhalmi, Dániel Szili, David E Szymkowski
Publikováno v:
Annals of the Rheumatic Diseases. 73:A37.1-A37
Background and Objectives CD19 is a B cell-specific marker present on pre-B cells, immature and mature B cells but lacking on plasma cells. CD19 is a positive co-receptor of B cell receptors (BCR) and a target of the tyrosine kinase Lyn in activated
Autor:
Dániel Szili, Gabriella Sármay, Judit Pozsgay, Zsuzsanna Bankó, Tamás Gáti, György Nagy, Bernadett Rojkovich
Publikováno v:
Annals of the Rheumatic Diseases. 72:A38.3-A39
Background and Objectives Rheumatoid arthritis (RA) is a common, relapsing autoimmune disease, which affects approximately 1% of the population worldwide. While the specific molecular events that lead to initiation and onset of RA are not known, an u
Publikováno v:
Annals of the Rheumatic Diseases. 70:A15-A15
Background and objectives Antigen driven positive selection of B cells depends on signals from B cell receptor (BCR) and a plethora of positive and negative regulating receptors determining B cells’ fate. Fas/CD95 mediated signals kill bystander or