Zobrazeno 1 - 10
of 520
pro vyhledávání: '"D, de Leon"'
Autor:
Herodes Guzman, Lauren M. Mitteer, Pan Chen, Christine A. Juliana, Kara Boodhansingh, Katherine Lord, Arupa Ganguly, Diva D. De Leon
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Hypoketotic hypoglycemia due to dysregulated insulin secretion is the most common cause of persistent hypoglycemia in children. However, this type of hypoglycemia can also result from defects in the insulin signaling pathway. Distinguishing between t
Externí odkaz:
https://doaj.org/article/c5be91d2122c4af19ee7444003ce8aed
Autor:
Herodes Guzman, Sahr Yazdani, Jennifer L. Harmon, Kimberly A. Chapman, Bernadette Vitola, Louise Pyle, Heather McKnight, Winnie Sigal, Katherine Lord, Diva D. De Leon, Nadia Merchant, Rebecca Ganetzky
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Timely diagnosis of persistent neonatal hypoglycemia is critical to prevent neurological sequelae, but diagnosis is complicated by the heterogenicity of the causes. We discuss two cases at separate institutions in which clinical management was fundam
Externí odkaz:
https://doaj.org/article/0327b11fedfc4e6d915f002fc3f7ef2e
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
For the past 70 years, controversy about hypoglycemia in newborn infants has focused on a numerical “definition of neonatal hypoglycemia”, without regard to its mechanism. This ignores the purpose of screening newborns for hypoglycemia, which is
Externí odkaz:
https://doaj.org/article/4f9df2a840964d5aac6c07aa2f8b0e48
Autor:
Indraneel Banerjee, Julie Raskin, Jean-Baptiste Arnoux, Diva D. De Leon, Stuart A. Weinzimer, Mette Hammer, David M. Kendall, Paul S. Thornton
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycemia in infants and children, and carries a considerable risk of neurological damage and developmental delays if diagnosis and treatment are delayed.
Externí odkaz:
https://doaj.org/article/0338a7325f634e74a9ff7f1f063adba0
Autor:
Winnie M. Sigal, Ohoud Alzahrani, Gabriela M. Guadalupe, Herodes Guzman, Jerilynn Radcliffe, Nina H. Thomas, Abbas F. Jawad, Diva D. De Leon
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
ObjectiveTo describe perinatal stress induced hyperinsulinism (PSIHI), determine the prevalence of neurodevelopmental differences, and identify risk factors for poor developmental prognosis.MethodsSubjects with a history of hyperinsulinism (HI) and p
Externí odkaz:
https://doaj.org/article/3440bddcf088413ca69b314033c02278
Autor:
Melinda Danowitz, Diva D. De Leon
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Incretin hormones play an important role in the regulation of glucose homeostasis through their actions on the beta cells and other tissues. Glucagon-like peptide-1 (GLP-1) and glucose dependent insulinotropic polypeptide (GIP) are the two main incre
Externí odkaz:
https://doaj.org/article/621e55e1c0134baa9e73a9a6375a23d4
Autor:
Indraneel Banerjee, Julie Raskin, Jean-Baptiste Arnoux, Diva D. De Leon, Stuart A. Weinzimer, Mette Hammer, David M. Kendall, Paul S. Thornton
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/92a48105e4b34c33bd28f6a5d4a5e74b
Autor:
Amita Tiyaboonchai, Fabian L. Cardenas-Diaz, Lei Ying, Jean Ann Maguire, Xiuli Sim, Chintan Jobaliya, Alyssa L. Gagne, Siddharth Kishore, Diana E. Stanescu, Nkecha Hughes, Diva D. De Leon, Deborah L. French, Paul Gadue
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 589-604 (2017)
Induced pluripotent stem cells were created from a pancreas agenesis patient with a mutation in GATA6. Using genome-editing technology, additional stem cell lines with mutations in both GATA6 alleles were generated and demonstrated a severe block in
Externí odkaz:
https://doaj.org/article/c8c6e7fbf6c14e58899ce5d301dc8248
Autor:
Kara E Boodhansingh, Zhongying Yang, Changhong Li, Pan Chen, Katherine Lord, Susan A Becker, Lisa J States, N Scott Adzick, Tricia Bhatti, Show-Ling Shyng, Arupa Ganguly, Charles A Stanley, Diva D De Leon
Publikováno v:
European Journal of Endocrinology. 187:301-313
Objective Congenital hyperinsulinism (HI) is the most common cause of persistent hypoglycemia in children. In addition to typical focal or diffuse HI, some cases with diazoxide-unresponsive congenital HI have atypical pancreatic histology termed Loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7033f1f22538ed7c7ccb84c7c0be3b42
https://doi.org/10.1530/eje-21-1095
https://doi.org/10.1530/eje-21-1095
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