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Akademický článek
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Publikováno v:
Journal of Neuroendocrinology. 8:457-464
The neuropeptides galanin and pituitary adenylate cyclase-activating peptide (PACAP) have been implicated in the physiological regulation of lactotroph function. Using the 235-1 clonal lactotroph rat cell line we have studied the signalling pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ab8e48cb86f59032320019341a52f1
https://doi.org/10.1046/j.1365-2826.1996.04747.x
https://doi.org/10.1046/j.1365-2826.1996.04747.x
Autor:
S-A, Hobson, A, Bacon, C R, Elliot-Hunt, F E, Holmes, N C H, Kerr, R, Pope, P, Vanderplank, D, Wynick
Publikováno v:
Experientia supplementum (2012). 102
The neuropeptide galanin is widely, but not ubiquitously, expressed in the adult nervous system. Its expression is markedly up-regulated in many neuronal tissues after nerve injury or disease. Over the last 10 years, we have demonstrated that the pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::90e90884c52b5591b1a777dd0b8c9f4b
https://pubmed.ncbi.nlm.nih.gov/21299059
https://pubmed.ncbi.nlm.nih.gov/21299059
Publikováno v:
Journal of Human Nutrition and Dietetics. 6:457-460
A patient with a pancreatic tumour suffered severe diarrhoea as a result of abnormal secretions of vasoactive intestinal polypeptide. Initial elemental feeding and continued nutritional support improved her nutritional status. The patient currently s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e231bb24c96ee0dfc98f66ac0b3bcef6
https://doi.org/10.1111/j.1365-277x.1993.tb00390.x
https://doi.org/10.1111/j.1365-277x.1993.tb00390.x
Autor:
Paul Purkiss, P. G. H. Byfield, Karen O. Akinsanya, David M. Smith, Ranjev Bhogal, Noboru Yanaihara, Mohammad A. Ghatei, Stephen R. Bloom, D. Wynick
Publikováno v:
Proceedings of the National Academy of Sciences. 90:4231-4235
Structure-activity studies demonstrate that galanin fragments 1-15 and 2-29 are fully active, whereas fragment 3-29 has been reported to be inactive, in a number of different in vivo models. M15, a chimeric peptide comprising galanin 1-13 and substan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b6a9852cd945cdf707c0eb25a04b70
https://doi.org/10.1073/pnas.90.9.4231
https://doi.org/10.1073/pnas.90.9.4231
Publikováno v:
Clinics in Dermatology. 11:93-97
The glucagonoma syndrome is now well characterised by a number of distinctive clinical and biochemical features associated with glucagon-producing islet cell tumours of the pancreas. In retrospect the first clear report of such a syndrome appeared in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1ae031d1e17e1a7306bebb62076a48
https://doi.org/10.1016/0738-081x(93)90103-j
https://doi.org/10.1016/0738-081x(93)90103-j
Autor:
D. C. Anderson, K. J. Moriarty, C. N. Hales, P. H. Winocour, S. R. Bloom, J. Adams, D. Allison, D. Wynick, R S Reeve
Publikováno v:
Postgraduate Medical Journal. 68:196-200
Summary A 15 year old girl with a family history of type 1 multiple endocrine adenomatosis presented with reversible neurological disturbances, hypoglycaemia and hyperinsulinaemia. Initial radiology was normal, but portal venous sampling suggested an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81c13915b6066f4c02481ef58f87a96
https://doi.org/10.1136/pgmj.68.797.196
https://doi.org/10.1136/pgmj.68.797.196
Publikováno v:
Journal of Endocrinology. 126:269-274
As the secretory granules of anterior pituitary cells fuse with the cell surface, there would appear to be sufficient hormone present on the cell surface to be labelled by polyclonal hormone antibodies and thus analysed by flow cytometry. We have the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51439bd6bdf42c9de8e726af99e95d50
https://doi.org/10.1677/joe.0.1260269
https://doi.org/10.1677/joe.0.1260269
Autor:
S. R. Bloom, D. Wynick
Publikováno v:
Digestion. 45:5-10
Ten patients with various metastatic pancreatic tumours have received Sandostatin (octreotide) for up to 5 years, initially 50 micrograms t.i.d. subcutaneously but increased over 6-12 months to 500 micrograms t.i.d. Three patients showed no biochemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6a0bc8b01af3445a8f8e9d2f704c5d
https://doi.org/10.1159/000200254
https://doi.org/10.1159/000200254