Zobrazeno 1 - 10
of 60
pro vyhledávání: '"D, Wiaderna"'
Autor:
S, Gralewicz, D, Wiaderna
Publikováno v:
Neurotoxicology. 22(1)
Trimethylbenzene (TMB), like xylene (dimethylbenzene), is a significant constituent of some industrial solvent mixtures. In earlier studies, we found that in the rat a subacute low-level inhalation exposure to some of the TMB isomers may result in be
Autor:
D, Wiaderna, T, Tomas
Publikováno v:
International journal of occupational medicine and environmental health. 13(4)
This study was performed to find out whether repeated exposure to toluene might lead to behavioural sensitization estimated on the basis of spontaneous locomotor activity of rats in an open field. As a reference compound amphetamine was used. Toluene
Publikováno v:
Acta neurobiologiae experimentalis. 60(3)
A certain proportion of laboratory rats of various strains show spontaneous nonconvulsive ECoG seizures in the form of bursts of spike-and-wave discharges (SWD). Since in the majority of behavioural experiments the EEG is not controlled, the experime
Publikováno v:
International journal of occupational medicine and environmental health. 13(1)
The purpose of this investigation was to compare the neurotoxic potential of trimethylbenzene (TMB) isomers (the solvents) with that of benzene derivatives with a smaller number of methyl groups (toluene). The experiments were performed on WAG/Rij ra
Publikováno v:
International journal of occupational medicine and environmental health. 12(4)
This study was performed to find out whether in acute exposure to trimethylbenzene (TMB) isomers the dose effect relationship is linear or biphasic. In experiments performed on rats, the effect of four solvents was studied: three TMB isomers: 1,3,5-T
Publikováno v:
International journal of occupational medicine and environmental health. 12(1)
In a series of acute experiments on rats the potential of toluene, mesitylene, hemimellitene and pseudocumene to affect the CNS function was assessed following an analysis of spontaneous and evoked hippocampal and cortical activity. The electrophysio
Publikováno v:
Medycyna pracy. 49(6)
The aim of this study was to assess the effect of four organic solvents (toluene, mesitylene, pseudocumene and hemimellitine) on the central nervous system (NCS) on the basis of changes in spontaneous EEG of the cerebral cortex and hippocampus functi
Publikováno v:
International journal of occupational medicine and environmental health. 11(4)
Trimethylbenzene isomers (TMBs): 1,2,4-TMB (pseudocumene--PS), 1,2,3-TMB (hemimellitene--HM) and 1,3,5-TMB (mesitylene--MES) are important constituents of solvent mixtures. In the US, the adopted TLV-TWA value for TMBs is 125 mg/m3 or 25 ppm (ACGIH 1
Publikováno v:
International journal of occupational medicine and environmental health. 10(2)
It has been hypothesized that exposure to neurotoxins may hasten the process of brain ageing. Volatile hydrocarbons are in common use as solvents and their neurotoxic properties are acknowledged. In the rat, the age-related neurodegenerative changes
Publikováno v:
Medycyna pracy. 48(2)
The goal of the study was to implement the method and to use it in identifying the extent of neurotoxic effect of organic solvents on the basis of changes in spontaneous (EEG) and evoked (evoked potentials) function of cerebral cortex and hippocamp i