Výsledky vyhledávání - "D, Westerling"

Akademický článek

Concentration-Effect Relationship after Intravenous Hydromorphone Administration: Use of An Effect Compartment Model and System Analysis to Minimize Hysteresis of Effects

Autor: D Westerling, P Hoglund

Publikováno v: Pain Research and Management, Vol 2, Iss 3, Pp 167-172 (1997)

OBJECTIVE: To investigate the concentration-effect relationship of hydromorphone by using two different methods to minimize the hysteresis between concentration and effects.

Externí odkaz: https://doaj.org/article/12593df6cdb74ff69ece308b74f1eacf

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Akademický článek

Analgesic and Nonanalgesic Effects of Intravenous Hydromorphone - Relation to Plasma Concentrations in Healthy Volunteers

Autor: D Westerling, H Bjork, P Svedman, P Hoglund

Publikováno v: Pain Research and Management, Vol 1, Iss 2, Pp 86-92 (1996)

OBJECTIVE: To investigate the analgesic and nonanalgesic effects and the pharmacokinetics of an intravenous infusion of 2 mg hydromorphone over 20 mins.

Externí odkaz: https://doaj.org/article/4f45ac202e5d45dbbceffd11ce921ad1

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Postoperative recovery evaluated with a new, tactile scale (TaS) in children undergoing ophthalmic surgery

Autor: D. Westerling

Publikováno v: Pain. 83:297-301

Following pediatric eye surgery, visual scales for assessment of recovery are inadequate due to impairment of vision. A tactile scale (TaS) was therefore developed and tested in a pilot-trial. Fifty children, 23 girls and 27 boys undergoing different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe9d1e362a98bd12804e9ee84c0d222
https://doi.org/10.1016/s0304-3959(99)00112-8

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The Influence of Preanalytical Factors on Concentrations of Morphine and Metabolites in Patients Receiving Morphine

Autor: H.-I. Bengtsson, Peter Höglund, D. Westerling, C. Thysell

Publikováno v: Pharmacology & Toxicology. 78:82-85

To examine the importance of preanalytical factors on the sample concentration of morphine, morphine-3-glucuronide and morphine-6-glucuronide, blood samples were drawn in sets of four from 21 patients who were given morphine due to chronic pain or as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49eda8482cd121158331e633bfb31225
https://doi.org/10.1111/j.1600-0773.1996.tb00184.x

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Analgesic and Nonanalgesic Effects of Intravenous Hydromorphone - Relation to Plasma Concentrations in Healthy Volunteers

Autor: P Svedman, D Westerling, H Bjork, P Hoglund

Publikováno v: Pain Research and Management, Vol 1, Iss 2, Pp 86-92 (1996)

OBJECTIVE:To investigate the analgesic and nonanalgesic effects and the pharmacokinetics of an intravenous infusion of 2 mg hydromorphone over 20 mins.DESIGN:Open study.SUBJECTS:Twelve healthy volunteers.MEASUREMENTS:The analgesic effect of hydromorp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cfd2100bc967b6434dfb57c6553394
https://doi.org/10.1155/1996/313012

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Plasma Concentrations of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide After Intravenous and Oral Administration to Healthy Volunteers

Autor: D Westerling, C Persson, P Höglund

Publikováno v: Therapeutic Drug Monitoring. 17:287-301

Healthy volunteers were given morphine as an i.v. infusion (10 mg), immediate release (IR) tablets (3 x 10 mg), and as a new controlled release (CR) tablet (30 mg) on separate occasions. Venous blood samples were analyzed for morphine, morphine-3-glu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da8ed08d8e6143372f08a9b74330df0
https://doi.org/10.1097/00007691-199506000-00013

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Transdermal administration of morphine to healthy subjects

Autor: Stefan Lundin, P Svedman, Peter Höglund, D Westerling

Publikováno v: British Journal of Clinical Pharmacology. 37:571-576

1. Twelve healthy subjects received 10 mg morphine HCl delivered transdermally from an occlusive reservoir applied to a small area of skin, painlessly de-epithelialised by vacuum suction. On a separate occasion, 10 mg morphine HCl was given as an i.v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e22760ce35c485ab276dd1c470fafdf
https://doi.org/10.1111/j.1365-2125.1994.tb04306.x

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Near fatal intoxication with controlled-release morphine tablets in a depressed woman

Autor: G. Eklundh, Juliette Säwe, D. Westerling

Publikováno v: Acta anaesthesiologica Scandinavica. 42(5)

Background: A 46-year-old woman suffering from a reactive depression was admitted to the emergency room in coma and with severe respiratory failure. She later developed cardiovascular instability and general convulsions. Two days following admission

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9957b7025549950e3ceeac55393f78
https://pubmed.ncbi.nlm.nih.gov/9605377

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Postoperative recovery after cholecystectomy by minilaparotomy: a randomized double-blind comparison between alpha-trinositol and placebo

Autor: D, Westerling, H H, Luttropp, T, Holmin, E, Landquist

Publikováno v: Pharmacologytoxicology. 81(6)

An opioid-sparing effect of alpha-trinositol (D-myo-inositol 1,2,6-trisphosphate) following cholecystectomy in otherwise healthy patients was suggested by a pilot study. In order to verify this result, pain, pain relief and nausea were studied in pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8f13b08768d6a05f370908c9f5c88b98
https://pubmed.ncbi.nlm.nih.gov/9444665

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