Zobrazeno 1 - 10
of 126
pro vyhledávání: '"D, Watrous"'
Autor:
Jelena Kornej, Maha A. Qadan, Mona Alotaibi, David R. Van Wagoner, Jeramie D. Watrous, Ludovic Trinquart, Sarah R. Preis, Darae Ko, Mohit Jain, Emelia J. Benjamin, Susan Cheng, Honghuang Lin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Chronic inflammation is a continuous low-grade activation of the systemic immune response. Whereas downstream inflammatory markers are associated with atrial fibrillation (AF), upstream inflammatory effectors including eicosanoids are less s
Externí odkaz:
https://doaj.org/article/c95baa991f634309b1c83caa9bab448f
Autor:
Viet T. Le, Stacey Knight, Jeramie D. Watrous, Mahan Najhawan, Khoi Dao, Raymond O. McCubrey, Tami L. Bair, Benjamin D. Horne, Heidi T. May, Joseph B. Muhlestein, John R. Nelson, John F. Carlquist, Kirk U. Knowlton, Mohit Jain, Jeffrey L. Anderson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionLong-chain omega-3 polyunsaturated fatty acids (OM3 PUFA) are commonly used for cardiovascular disease prevention. High-dose eicosapentaenoic acid (EPA) is reported to reduce major adverse cardiovascular events (MACE); however, a combined
Externí odkaz:
https://doaj.org/article/a44e80d84b8a40ba8d46716230f9431b
Autor:
André A. Weber, Xiaojing Yang, Elvira Mennillo, Jeffrey Ding, Jeramie D. Watrous, Mohit Jain, Shujuan Chen, Michael Karin, Robert H. Tukey
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Triclosan is an antimicrobial additive in consumer products that has been detected in human breast milk. Here the authors report that exposure of pregnant mice to triclosan leads to lactational exposure to newborns and the development of liver steato
Externí odkaz:
https://doaj.org/article/849d3928eb6e414aa409570b1972faf3
Autor:
Bettina Mittendorfer, Brandon D. Kayser, Mihoko Yoshino, Jun Yoshino, Jeramie D. Watrous, Mohit Jain, J. Christopher Eagon, Bruce W. Patterson, Samuel Klein
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
BACKGROUND There is considerable heterogeneity in the effect of weight loss on metabolic function in people with obesity.METHODS We evaluated muscle and liver insulin sensitivity, body composition, and circulating factors associated with insulin acti
Externí odkaz:
https://doaj.org/article/23ffeddd40944b2ab447bedb3aaf9757
Autor:
Xiaojing Chu, Martin Jaeger, Joep Beumer, Olivier B. Bakker, Raul Aguirre-Gamboa, Marije Oosting, Sanne P. Smeekens, Simone Moorlag, Vera P. Mourits, Valerie A. C. M. Koeken, Charlotte de Bree, Trees Jansen, Ian T. Mathews, Khoi Dao, Mahan Najhawan, Jeramie D. Watrous, Irma Joosten, Sonia Sharma, Hans J. P. M. Koenen, Sebo Withoff, Iris H. Jonkers, Romana T. Netea-Maier, Ramnik J. Xavier, Lude Franke, Cheng-Jian Xu, Leo A. B. Joosten, Serena Sanna, Mohit Jain, Vinod Kumar, Hans Clevers, Cisca Wijmenga, Mihai G. Netea, Yang Li
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-22 (2021)
Abstract Background Recent studies highlight the role of metabolites in immune diseases, but it remains unknown how much of this effect is driven by genetic and non-genetic host factors. Result We systematically investigate circulating metabolites in
Externí odkaz:
https://doaj.org/article/c356b25dd4854dcbb5ff8d2fda446129
Autor:
Aaro Salosensaari, Ville Laitinen, Aki S. Havulinna, Guillaume Meric, Susan Cheng, Markus Perola, Liisa Valsta, Georg Alfthan, Michael Inouye, Jeramie D. Watrous, Tao Long, Rodolfo A. Salido, Karenina Sanders, Caitriona Brennan, Gregory C. Humphrey, Jon G. Sanders, Mohit Jain, Pekka Jousilahti, Veikko Salomaa, Rob Knight, Leo Lahti, Teemu Niiranen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Gut microbiome composition has a role in health and disease. Here the authors show that microbiome signatures related to the Enterobacteriaceae family are associated with cause-specific mortality risk in a well phenotyped Finish population over a 15-
Externí odkaz:
https://doaj.org/article/2f2331dcc0f1446d924aa1e1d18fab05
Autor:
Stephen D. Watrous
Stephen D. Watrous provides a complete volume of pertinent information by and about John Ledyard, one of the most amazing explorers of all time. Including Ledyard's own journal, letters between him and others, particularly Thomas Jefferson, and biogr
Autor:
Mohammad Zulkifli, John K. Neff, Shrishiv A. Timbalia, Natalie M. Garza, Yingqi Chen, Jeramie D. Watrous, Marta Murgia, Prachi P. Trivedi, Steven K. Anderson, Dhanendra Tomar, Roland Nilsson, Muniswamy Madesh, Mohit Jain, Vishal M. Gohil
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Although some fungal mitochondria lack the calcium uniporter, many intriguingly encode homologs of the uniporter assembly factor MCUR1. Here, the authors show that in budding yeast, the MCUR1 homologs Put6 and Put7 regulate mitochondrial proline meta
Externí odkaz:
https://doaj.org/article/389bd4b04d3b4af58e574df071abb507
Autor:
Jaakko Tuomilehto, Veikko Salomaa, Marko Salmi, Sirpa Jalkanen, Ramachandran S Vasan, Pekka Jousilahti, Michael Inouye, Susan Cheng, Aki S Havulinna, Teemu J Niiranen, Karolina Tuomisto, Joonatan Palmu, Tao Long, Jeramie D Watrous, Kysha Mercader, Kim A Lagerborg, Allen Andres, Mohit Jain
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/ab77bcf45cdf42c99fd539608c202991
Autor:
Jeffry C. Granados, Jeramie D. Watrous, Tao Long, Sara Brin Rosenthal, Susan Cheng, Mohit Jain, Sanjay K. Nigam
Publikováno v:
Metabolites, Vol 13, Iss 2, p 171 (2023)
Drug transporters and drug-metabolizing enzymes are primarily known for their role in the absorption, distribution, metabolism, and excretion (ADME) of small molecule drugs, but they also play a key role in handling endogenous metabolites. Recent cro
Externí odkaz:
https://doaj.org/article/2111cada55f54b5cbd515d6e41bf142b