Zobrazeno 1 - 10
of 111
pro vyhledávání: '"D, Tatman"'
Autor:
Philip D. Tatman, David P. Kao, Kathryn C. Chatfield, Ian A. Carroll, Jessica A. Wagner, Eric R. Jonas, Carmen C. Sucharov, J. David Port, Brian D. Lowes, Wayne A. Minobe, Sophia P. Huebler, Anis Karimpour-Fard, Erin M. Rodriguez, Stephen B. Liggett, Michael R. Bristow
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
We investigated the extent, biologic characterization, phenotypic specificity, and possible regulation of a β1-adrenergic receptor–linked (β1-AR–linked) gene signaling network (β1-GSN) involved in left ventricular (LV) eccentric pathologic rem
Externí odkaz:
https://doaj.org/article/cc7c56d0fed841659469accaddf4f47a
Autor:
Philip D. Tatman, Tadeusz H. Wroblewski, Anthony R. Fringuello, Samuel R. Scherer, William B. Foreman, Denise M. Damek, Kevin O. Lillehei, Randy L. Jensen, A. Samy Youssef, D. Ryan Ormond, Michael W. Graner
Publikováno v:
World Neurosurgery. 162:e99-e119
Meningiomas are a common primary central nervous system tumor that lack a U.S. Food and Drug Administration-approved pharmacotherapy. Approximately 20%-35% of meningiomas are classified as higher grade with poor outcome, whereas patients with lower-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305a4e4ea8e6c1469170369f09da4273
https://doi.org/10.1016/j.wneu.2022.02.108
https://doi.org/10.1016/j.wneu.2022.02.108
Autor:
Danielle R Bruns, Philip D Tatman, Roshni S Kalkur, R Dale Brown, Kurt R Stenmark, Peter M Buttrick, Lori A Walker
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220573 (2019)
RationaleIn virtually all models of heart failure, prognosis is determined by right ventricular (RV) function; thus, understanding the cellular mechanisms contributing to RV dysfunction is critical. Whole organ remodeling is associated with cell-spec
Externí odkaz:
https://doaj.org/article/4b5c61dd88c746749ef7939aab96ddac
Publikováno v:
bioRxiv
Cells require the ability to adapt to changing environmental conditions, however, it is unclear how these changes elicit stable permanent changes in genomes. We demonstrate that, in response to environmental metal exposure, the metallothionein (MT) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f03268c48b6ddc87334d443d60a806
https://doi.org/10.1101/2023.05.08.539886
https://doi.org/10.1101/2023.05.08.539886
Autor:
Matthew S. Stratton, Charles Y. Lin, Priti Anand, Philip D. Tatman, Bradley S. Ferguson, Sean T. Wickers, Amrut V. Ambardekar, Carmen C. Sucharov, James E. Bradner, Saptarsi M. Haldar, Timothy A. McKinsey
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1366-1378 (2016)
BRD4 governs pathological cardiac gene expression by binding acetylated chromatin, resulting in enhanced RNA polymerase II (Pol II) phosphorylation and transcription elongation. Here, we describe a signal-dependent mechanism for the regulation of BRD
Externí odkaz:
https://doaj.org/article/df7e3bb8863e4f5b8a372f88ea649cde
Autor:
Joseph C. Cleveland, Timothy A. McKinsey, Amrut V. Ambardekar, BS Philip D. Tatman, Madeleine E. Lemieux, Matthew S. Stratton, Evgenia Dobrinskikh, Kendall S. Hunter, Karen S. Moulton, Mary C.M. Weiser-Evans, Rubin M. Tuder
Publikováno v:
Journal of the American College of Cardiology. 78:1782-1795
Background The effects of nonphysiological flow generated by continuous-flow (CF) left ventricular assist devices (LVADs) on the aorta remain poorly understood. Objectives The authors sought to quantify indexes of fibrosis and determine the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::604b947cd99a4f062152b498c3777530
https://doi.org/10.1016/j.jacc.2021.08.047
https://doi.org/10.1016/j.jacc.2021.08.047
Autor:
Philip D. Tatman, Tadeusz H. Wroblewski, Anthony R. Fringuello, Samuel R. Scherer, William B. Foreman, Denise M. Damek, A. Samy Youssef, Kevin O. Lillehei, Randy L. Jensen, Michael W. Graner, D. Ryan Ormond
Publikováno v:
Journal of Neurological Surgery Part B: Skull Base.
Background Epigenetics may predict treatment sensitivity and clinical course for patients with meningiomas more accurately than histopathology. Nonetheless, targeting epigenetic mechanisms is understudied for pharmacotherapeutic development for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8636af12d529f09c216e25c7dad4f241
https://doi.org/10.1055/a-1885-1257
https://doi.org/10.1055/a-1885-1257
Autor:
Philip D. Tatman, Joshua C. Black
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2310
Extrachromosomal circular DNA has emerged as a frequent genomic alteration in tumors. High numbers of circular DNAs correspond to poor prognosis suggesting an important function in tumor biology. However, despite mounting evidence supporting the impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5496e924640ff93ec6eeb0571a441cba
https://pubmed.ncbi.nlm.nih.gov/35565439
https://pubmed.ncbi.nlm.nih.gov/35565439
Autor:
Samuel Han, Sachin Wani, Hazem T. Hammad, Mihir S. Wagh, Sanjana Mehrotra, Raj J. Shah, Brian C. Brauer, Steven A. Edmundowicz, Philip D. Tatman, Augustin Attwell
Publikováno v:
Digestive Diseases and Sciences. 66:1276-1284
Biliary stricture evaluation with brush cytology and intraductal forceps biopsy carries a low sensitivity, but the combination of newer modalities may improve sensitivity. To determine whether the addition of advanced modalities increases diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e75a67d4d64c098f9f7675758e3628d
https://doi.org/10.1007/s10620-020-06335-x
https://doi.org/10.1007/s10620-020-06335-x
Autor:
Tadeusz H. Wroblewski, Philip D. Tatman, Anthony R. Fringuello, Samuel R. Scherer, William B. Foreman, Denise M. Damek, Kevin Lillehei, Randy L. Jenson, A. Samy Youssef, D. Ryan Ormond, Michael W. Graner
Publikováno v:
31st Annual Meeting North American Skull Base Society.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5335c04ee68792a9960e0440153e6865
https://doi.org/10.1055/s-0042-1743638
https://doi.org/10.1055/s-0042-1743638