Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning

Autor: Zhaoxiang Cai, Sofia Apolinário, Ana R. Baião, Clare Pacini, Miguel D. Sousa, Susana Vinga, Roger R. Reddel, Phillip J. Robinson, Mathew J. Garnett, Qing Zhong, Emanuel Gonçalves

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

Abstract Integrating diverse types of biological data is essential for a holistic understanding of cancer biology, yet it remains challenging due to data heterogeneity, complexity, and sparsity. Addressing this, our study introduces an unsupervised d

Externí odkaz: https://doaj.org/article/58b951e3cf64437ebfa82518119ab27f

Effects of grass species and harvest date on cell wall components and feed efficiency of dairy cows

Autor: D. Sousa, M. Murphy, R. Hatfield, E. Nadeau

Publikováno v: Animal, Vol 18, Iss 8, Pp 101256- (2024)

There is a balance between DM yield and feed value when choosing types of grasses on a farm depending on the acreages of farmland and types of ruminants to be fed. Therefore, optimisation of the harvest strategy for grass silage is important for prof

Externí odkaz: https://doaj.org/article/c007bfcb25fd47248b49f3d738fd1f95

Leprosy and tuberculosis control scenario of the national program for the improvement of access and quality of primary care in Brazil

Autor: Glenda R. O. N. Ferreira, Amanda L. C. Miranda, Viviane A. Farias, Melissa B. Martins, Débora Talitha Neri, William D. Borges, Carlos Leonardo F. Cunha, Geyse Aline R. Dias, Dirceu C. Santos, Fabianne J. D. Sousa

Publikováno v: BMC Health Services Research, Vol 23, Iss 1, Pp 1-10 (2023)

Abstract Background In Brazil, despite advances in public health policies aimed at eliminating and controlling infectious and parasitic diseases, the incidence of neglected diseases is still high. The epidemiological scenario in Brazil of diseases su

Externí odkaz: https://doaj.org/article/10ef20ce3b7c4fe58d797b6e93966074

Insecticide paints: a new community strategy for controlling dengue and zika mosquito vectors in Cabo Verde

Autor: Lara Ferrero Gómez, Hélio D. Ribeiro Rocha, Ignacio Gil Torró, Irene Serafín Pérez, Deinilson Conselheiro Mendes, Keily L. Fonseca Silva, Davidson D. Sousa Rocha Monteiro, Jailson P. Tavares Dos Reis, Silvânia Veiga Leal, Luis F. Vitória Soulé, Jailton C. Fortes, Maria da Luz Lima Mendonça, Eva Caballero Mendez, Basilio Valladares Hernández

Publikováno v: Frontiers in Tropical Diseases, Vol 5 (2024)

BackgroundCabo Verde, an island country in West Africa, has been affected since human colonization by epidemics of vector-borne diseases with major epidemics of dengue and zika in recent years. Although there is a national program for integrated vect

Externí odkaz: https://doaj.org/article/d1dfe8deaee541718678721fc421678f

ABC2-SPH risk score for in-hospital mortality in COVID-19 patients: development, external validation and comparison with other available scores

Autor: Milena S. Marcolino, MD, MSc, PhD, Magda C. Pires, PhD, Lucas Emanuel F. Ramos, Rafael T. Silva, Luana M. Oliveira, MSc, Rafael L.R. Carvalho, PhD, Rodolfo Lucas S. Mourato, Adrián Sánchez-Montalvá, MD, PhD, Berta Raventós, MSc, Fernando Anschau, MD, PhD, José Miguel Chatkin, MD, PhD, Matheus C.A. Nogueira, MD, Milton H. Guimarães-Júnior, MD, MSc, Giovanna G. Vietta, MD, PhD, Helena Duani, MD, PhD, Daniela Ponce, MD, PhD, Patricia K. Ziegelmann, PhD, Luís C. Castro, PhD, Karen B. Ruschel, PhD, Christiane C.R. Cimini, MD, MSc, Saionara C. Francisco, MSc, Maiara A. Floriani, MSc, Guilherme F. Nascimento, MSc, Bárbara L. Farace, MD, Luanna S. Monteiro, MD, Maira V.R. Souza-Silva, MD, Thais L.S. Sales, MSc, Karina Paula M.P. Martins, MD, MSc, Israel J. Borges do Nascimento, Tatiani O. Fereguetti, MD, Daniel T.M.O. Ferrara, Fernando A. Botoni, MD, Ana Paula B.S. Etges, PhD, Alexandre V. Schwarzbold, MD, PhD, Amanda O. Maurílio, MD, Ana Luiza B.A. Scotton, MD, André P. Weber, André S.M. Costa, MD, Andressa B. Glaeser, Angélica Aparecida C. Madureira, MD, Angelinda R. Bhering, MD, Bruno Mateus de Castro, Carla Thais C.A. da Silva, Carolina M. Ramos, MD, Caroline D. Gomes, Cíntia A. de Carvalho, Daniel V. Silveira, MD, MSc, Edilson Cezar, Elayne C. Pereira, PhD, Emanuele Marianne S. Kroger, MD, Felipe B. Vallt, Fernanda B. Lucas, MD, Fernando G. Aranha, MD, Frederico Bartolazzi, MD, MSc, Gabriela P. Crestani, Gisele A.N. Bastos, MD, ScD, Glícia Cristina de C. Madeira, MD, Helena Carolina Noal, MSc, Heloisa R. Vianna, MD, MSc, Henrique C. Guimarães, MD, PhD, Isabela M. Gomes, Israel Molina, MD, PhD, Joanna d'Arc L. Batista, MD, PhD, Joice C. de Alvarenga, MD, Júlia D.S.S. Guimarães, MD, Júlia D.P. de Morais, MD, Juliana M. Rugolo, Karen Cristina J.R. Pontes, Kauane Aline M. dos Santos, Leonardo S. de Oliveira, Lílian S. Pinheiro, Liliane S. Pacheco, MD, MSc, Lucas de D. Sousa, MD, Luciana S.F. Couto, Luciane Kopittke, PhD, Luis Cesar S. de Moura, PhD, Luisa Elem A. Santos, Máderson A.S. Cabral, MD, Maíra D. Souza, MD, Marcela G.T. Tofani, MD, Marcelo Carneiro, MD, PhD, Maria Angélica P. Ferreira, PhD, Maria Aparecida C. Bicalho, MD, PhD, Maria Clara P.B. Lima, Mariana F. Godoy, MD, Marilia M.A. Cardoso, PhD, Meire P. Figueiredo, Natália C.S. Sampaio, Natália L. Rangel, MD, Natália T. Crespo, MD, Neimy R. de Oliveira, MD, Pedro L. Assaf, MD, Petrônio José de L. Martelli, MD, PhD, Rafaela S.C. Almeida, Raphael C. Martins, Raquel Lutkmeier, Reginaldo Aparecido Valacio, Renan G. Finger, MD, Ricardo B. Cardoso, MSc, Roberta Pozza, MD, PhD, Roberta X. Campos, MD, Rochele M. Menezes, MD, Roger M. de Abreu, MD, Rufino de F. Silva, MD, Silvana M.M. Guimarães, MD, Silvia F. Araújo, MD, Susany Anastácia Pereira, Talita F. Oliveira, MD, Tatiana Kurtz, MD, PhD, Thainara C. de Oliveira, Thaíza Simônia M.A. Araújo, Thulio Henrique O. Diniz, MD, Veridiana B. dos Santos, Virginia Mara R. Gomes, Vitor Augusto L. do Vale, Yuri C. Ramires, MD, Eric Boersma, MD, PhD, Carisi A. Polanczyk, MD, PhD

Publikováno v: International Journal of Infectious Diseases, Vol 110, Iss , Pp 281-308 (2021)

Objectives: The majority of available scores to assess mortality risk of coronavirus disease 2019 (COVID-19) patients in the emergency department have high risk of bias. Therefore, this cohort aimed to develop and validate a score at hospital admissi

Externí odkaz: https://doaj.org/article/72d2ab38013b4648b8a55f0904cc1d7a