Zobrazeno 1 - 10
of 1 687
pro vyhledávání: '"D, Sheppard"'
Autor:
Wisam Barkho, Nathan C. Carnes, Claire A. Kolaja, Xin M. Tu, Satbir K. Boparai, Sheila F. Castañeda, Beverly D. Sheppard, Jennifer L. Walstrom, Jennifer N. Belding, Rudolph P. Rull, the Millennium Cohort Study Team
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The Millennium Cohort Study is a longitudinal study which collects self-reported data from surveys to examine the long-term effects of military service. Participant nonresponse to follow-up surveys presents a potential threat to the validity
Externí odkaz:
https://doaj.org/article/49f6b37b04064e0c8118b4186a6adcf2
Autor:
Ahmad M. Fahmy, Jennifer S. Harthan, David G. Evans, Jack V. Greiner, Joseph Tauber, John D. Sheppard, Sonja Krösser, Jason L. Vittitow
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
BackgroundDry eye disease (DED) is commonly caused by excessive tear film evaporation due to Meibomian gland dysfunction (MGD). There is a need for DED treatment options that address tear evaporation and benefit patients across a broad range of demog
Externí odkaz:
https://doaj.org/article/d4572072e7f04837aa628162d8099232
Autor:
Claire A. Kolaja, Jennifer N. Belding, Satbir K. Boparai, Sheila F. Castañeda, Toni Rose Geronimo-Hara, Teresa M. Powell, Xin M. Tu, Jennifer L. Walstrom, Beverly D. Sheppard, Rudolph P. Rull, for the Millennium Cohort Study Team
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Patterns of survey response and the characteristics associated with response over time in longitudinal studies are important to discern for the development of tailored retention efforts aimed at minimizing response bias. The Mille
Externí odkaz:
https://doaj.org/article/ecae1a2c3271474cb54aa40e4b595640
Autor:
Maria Davern, Cillian O’ Donovan, Noel E. Donlon, Eimear Mylod, Caoimhe Gaughan, Anshul Bhardwaj, Andrew D. Sheppard, Dara Bracken-Clarke, Christine Butler, Narayanasamy Ravi, Claire L. Donohoe, John V. Reynolds, Joanne Lysaght, Melissa J. Conroy
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 819 (2024)
The presence of an immunosuppressive tumour microenvironment in oesophageal adenocarcinoma (OAC) is a major contributor to poor responses. Novel treatment strategies are required to supplement current regimens and improve patient survival. This study
Externí odkaz:
https://doaj.org/article/3ca4eb6b6a0845a7a2adb872372af596
Autor:
John D. Sheppard, Kelly K. Nichols
Publikováno v:
Ophthalmology and Therapy, Vol 12, Iss 3, Pp 1397-1418 (2023)
Abstract Meibomian gland dysfunction (MGD) is highly prevalent and is the leading cause of evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum secretion and/or a change in meibum composition that results in the disruption
Externí odkaz:
https://doaj.org/article/3a3026df0080465282cc234157a79e6a
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Pharmaceuticals derived from benzylisoquinoline alkaloids find application in modern medicine. Here, the authors report the design of a parallel enzymatic cascade to generate halogenated benzylisoquinoline alkaloids, that included engineering of tyro
Externí odkaz:
https://doaj.org/article/b0c5ff28660344648acc5d5a20d80773
Autor:
Maria Davern, Caoimhe Gaughan, Fiona O’ Connell, Brendan Moran, Eimear Mylod, Andrew D. Sheppard, Sinead Ramjit, Jasmine Yun-Tong Kung, James J. Phelan, Matthew G. Davey, Eanna J. Ryan, Christine Butler, Laura Quinn, Claudine Howard, Emily Tone, Eimear Phoenix, Waqas T. Butt, Niamh Lynam-Lennon, Stephen G. Maher, Narayanasamy Ravi, Claire L. Donohoe, John V. Reynolds, Joanne Lysaght, Noel E. Donlon
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThis timely study assesses the immunosuppressive effects of surgery on cytotoxic Th1-like immunity and investigates if immune checkpoint blockade (ICB) can boost Th1-like immunity in the perioperative window in upper gastrointestinal canc
Externí odkaz:
https://doaj.org/article/e9a76b77fe4448bca0dc1485f4477ae2
Autor:
Francine E. Darroch, Sydney V. M. Smith, Madeleine D. Sheppard-Perkins, Audrey R. Giles, Dylan Wykes
Publikováno v:
Frontiers in Sports and Active Living, Vol 5 (2023)
The primary objective of this community-based participatory research is to explore the impacts of COVID-19 and the delayed Tokyo 2020 Olympic Games on world-class and elite/international-class parenting and pregnant athletes. Participants in this stu
Externí odkaz:
https://doaj.org/article/8df2e61b26094f58b7b0d7d1cd365965
Autor:
Bradley L. Young, MD, Evan D. Sheppard, MD, Sierra Phillips, MD, Trevor M. Stubbs, MD, Jun Kit He, MD, Andrew Moon, MD, Martim C. Pinto, MD, Gerald McGwin, PhD, Eugene William Brabston, MD, Shawn R. Gilbert, MD, Brent A. Ponce, MD
Publikováno v:
JSES International, Vol 6, Iss 3, Pp 463-467 (2022)
Background: Tendon-to-bone (TtB) healing is essential for successful rotator cuff repair (RCR). This study aimed to investigate if caffeine intake impaired TtB healing in a rat RCR model. Methods: Seventy-two rats were randomized into a caffeinated g
Externí odkaz:
https://doaj.org/article/9b3d629dd94142bbb63bc4fbdb4039f0
Autor:
Maria Davern, Rebecca M. O’ Brien, Jason McGrath, Noel E. Donlon, Ashanty M. Melo, Croí E. Buckley, Andrew D. Sheppard, John V. Reynolds, Niamh Lynam-Lennon, Stephen G. Maher, Joanne Lysaght
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Chemotherapy upregulates immune checkpoint (IC) expression on the surface of tumour cells and IC-intrinsic signalling confers a survival advantage against chemotherapy in several cancer-types including oesophageal adenocarcinoma (OAC). Howev
Externí odkaz:
https://doaj.org/article/dc1658cc2c1c4f7893802d0bf5e392a0