Zobrazeno 1 - 10
of 174
pro vyhledávání: '"D, Pins"'
Publikováno v:
Journal of Biomedical Materials Research Part A.
Autor:
Meagan E. Carnes, George D. Pins
Publikováno v:
Bioengineering, Vol 7, Iss 3, p 85 (2020)
Millions of Americans suffer from skeletal muscle injuries annually that can result in volumetric muscle loss (VML), where extensive musculoskeletal damage and tissue loss result in permanent functional deficits. In the case of small-scale injury ske
Externí odkaz:
https://doaj.org/article/579c6ab100cd48b698081aaf233ecf89
Autor:
Joshua R. Gershlak, George D. Pins, Maria Vratsanos, Katrina J. Hansen, Marianne Kanellias, Megan O. Chrobak, Glenn R. Gaudette
Publikováno v:
ACS biomaterials scienceengineering. 3(7)
The ability to modulate the mechanical properties, and cell alignment within a cardiac patch without hindering cell functionality may have significant impact on developing therapies for treating myocardial infarctions. We developed fibrin-based compo
Autor:
George D. Pins, Meagan E. Carnes
Publikováno v:
Bioengineering, Vol 7, Iss 85, p 85 (2020)
Bioengineering
Bioengineering
Millions of Americans suffer from skeletal muscle injuries annually that can result in volumetric muscle loss (VML), where extensive musculoskeletal damage and tissue loss result in permanent functional deficits. In the case of small-scale injury ske
Autor:
Meagan E. Carnes, Jane W. Njihia, George D. Pins, Jeannine M. Coburn, Cailin R. Gonyea, Rebecca G. Mooney
Publikováno v:
Tissue Eng Part C Methods
Horseradish peroxidase (HRP) has been investigated as a catalyst to crosslink tissue-engineered hydrogels because of its mild reaction conditions and ability to modulate the mechanical properties of the matrix. Here, we report the results of the firs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b359c8846524c5ba58e65563832ebf85
https://europepmc.org/articles/PMC7310227/
https://europepmc.org/articles/PMC7310227/
Publikováno v:
J Biomed Mater Res A
Myocardial infarction (MI) results in the death of cardiac tissue, decreases regional contraction, and can lead to heart failure. Tissue engineered cardiac patches containing human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) can r
Autor:
Meagan E. Carnes, George D. Pins
Publikováno v:
J Biomed Mater Res B Appl Biomater
To regenerate functional muscle tissue, engineered scaffolds should impart topographical features to induce myoblast alignment by a phenomenon known as contact guidance. Myoblast alignment is an essential step towards myotube formation, which is guid
Publikováno v:
Current Stem Cell Reports. 2:147-157
Native tissue structures possess elaborate extracellular matrix (ECM) architectures that inspire the design of fibrous structures in the field of regenerative medicine. We review the literature with respect to the successes and failures, as well as t
Autor:
Yeonsik Noh, Bersain A. Reyes, Ki H. Chon, Jennifer Molignano, John P. Florian, Justin R. Bales, Amanda L. Clement, George D. Pins
Publikováno v:
Annals of Biomedical Engineering. 44:2464-2479
In this study, we evaluated the performance of two novel conductive carbon black (CB) and polydimethlysiloxane (PDMS) bio-potential electrodes, with and without an integrated flexible copper mesh, against commercially available electrodes (Polar(®)
Publikováno v:
Biomaterials. 72:49-60
A significant challenge in the design and development of biomaterial scaffolds is to incorporate mechanical and biochemical cues to direct organized tissue growth. In this study, we investigated the effect of hepatocyte growth factor (HGF) loaded, cr