Zobrazeno 1 - 10
of 254
pro vyhledávání: '"D, Pagel"'
Autor:
Philipp Knopf, Dimitri Stowbur, Sabrina H. L. Hoffmann, Natalie Hermann, Andreas Maurer, Valentina Bucher, Marilena Poxleitner, Bredi Tako, Dominik Sonanini, Balaji Krishnamachary, Sanhita Sinharay, Birgit Fehrenbacher, Irene Gonzalez-Menendez, Felix Reckmann, David Bomze, Lukas Flatz, Daniela Kramer, Martin Schaller, Stephan Forchhammer, Zaver M. Bhujwalla, Leticia Quintanilla-Martinez, Klaus Schulze-Osthoff, Mark D. Pagel, Marieke F. Fransen, Martin Röcken, André F. Martins, Bernd J. Pichler, Kamran Ghoreschi, Manfred Kneilling
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Immune checkpoint inhibitors have revolutionized cancer therapy, yet the efficacy of these treatments is often limited by the heterogeneous and hypoxic tumor microenvironment (TME) of solid tumors. In the TME, programmed death-ligand 1 (PD-L
Externí odkaz:
https://doaj.org/article/b3fa661fa2c8409a83b991ccda94efe7
Autor:
Zijian Zhou, Beatriz E. Adrada, Rosalind P. Candelaria, Nabil A. Elshafeey, Medine Boge, Rania M. Mohamed, Sanaz Pashapoor, Jia Sun, Zhan Xu, Bikash Panthi, Jong Bum Son, Mary S. Guirguis, Miral M. Patel, Gary J. Whitman, Tanya W. Moseley, Marion E. Scoggins, Jason B. White, Jennifer K. Litton, Vicente Valero, Kelly K. Hunt, Debu Tripathy, Wei Yang, Peng Wei, Clinton Yam, Mark D. Pagel, Gaiane M. Rauch, Jingfei Ma
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Neoadjuvant systemic therapy (NAST) followed by surgery are currently standard of care for TNBC with 50-60% of patients achieving pathologic complete response (p
Externí odkaz:
https://doaj.org/article/9d1afc4d0a46451ea11ba6d0e3bea0a2
Autor:
Alyssa C. Pollard, Jorge de la Cerda, F. William Schuler, Charles V. Kingsley, Seth T. Gammon, Mark D. Pagel
Publikováno v:
EJNMMI Physics, Vol 9, Iss 1, Pp 1-14 (2022)
Abstract Background PET/MRI is an attractive imaging modality due to the complementary nature of MRI and PET. Obtaining high quality small animal PET/MRI results is key for the translation of novel PET/MRI agents and techniques to the radiology clini
Externí odkaz:
https://doaj.org/article/d93e605302514b009677033ee7ce45ce
Autor:
Hisham Assi, Rui Cao, Madhura Castelino, Ben Cox, Fiona J. Gilbert, Janek Gröhl, Kurinchi Gurusamy, Lina Hacker, Aoife M. Ivory, James Joseph, Ferdinand Knieling, Martin J. Leahy, Ledia Lilaj, Srirang Manohar, Igor Meglinski, Carmel Moran, Andrea Murray, Alexander A. Oraevsky, Mark D. Pagel, Manojit Pramanik, Jason Raymond, Mithun Kuniyil Ajith Singh, William C. Vogt, Lihong Wang, Shufan Yang, Members of IPASC, Sarah E. Bohndiek
Publikováno v:
Photoacoustics, Vol 32, Iss , Pp 100539- (2023)
Photoacoustic imaging (PAI), also referred to as optoacoustic imaging, has shown promise in early-stage clinical trials in a range of applications from inflammatory diseases to cancer. While the first PAI systems have recently received regulatory app
Externí odkaz:
https://doaj.org/article/bf32a26f811941769e84183116fd967b
Autor:
Rachel A. High, Edward A. Randtke, Kyle M. Jones, Leila R. Lindeman, Jacqueline C. Ma, Shu Zhang, Lucia G. LeRoux, Mark D. Pagel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 11, Pp 1085-1090 (2019)
Differentiating pancreatitis from pancreatic cancer would improve diagnostic specificity, and prognosticating pancreatitis that progresses to pancreatic cancer would also improve diagnoses of pancreas pathology. The high glycolytic metabolism of panc
Externí odkaz:
https://doaj.org/article/81b9afcb46554ebd97236aedcf38e4f4
Autor:
Samantha J. Paulsen, Trevor M. Mitcham, Charlene S. Pan, James Long, Bagrat Grigoryan, Daniel W. Sazer, Collin J. Harlan, Kevin D. Janson, Mark D. Pagel, Jordan S. Miller, Richard R. Bouchard
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Modern ultrasound (US) imaging is increasing its clinical impact, particularly with the introduction of US-based quantitative imaging biomarkers. Continued development and validation of such novel imaging approaches requires imaging phantoms that rec
Externí odkaz:
https://doaj.org/article/90caa39587394fac9496fa4d0d45a4a5
Autor:
Alyssa C. Pollard, Jorge de la Cerda, F. William Schuler, Tyler R. Pollard, Aikaterini Kotrotsou, Federica Pisaneschi, Mark D. Pagel
Publikováno v:
Biosensors, Vol 12, Iss 2, p 134 (2022)
Acidosis is a useful biomarker for tumor diagnoses and for evaluating early response to anti-cancer treatments. Despite these useful applications, there are few methods for non-invasively measuring tumor extracellular pH, and none are routinely used
Externí odkaz:
https://doaj.org/article/6f775603ae284967b008fa378f78c0f7
Autor:
Clinton W. Hupple, Stefan Morscher, Neal C. Burton, Mark D. Pagel, Lacey R. McNally, Julio Cárdenas-Rodríguez
Publikováno v:
Photoacoustics, Vol 10, Iss , Pp 54-64 (2018)
MultiSpectral Optoacoustic Tomography (MSOT) is an emerging imaging technology that allows for data acquisition at high spatial and temporal resolution. These imaging characteristics are advantageous for Dynamic Contrast Enhanced (DCE) imaging that c
Externí odkaz:
https://doaj.org/article/cc3081c9f6b44b70b94e5d3d582bc53a
Autor:
A. Peter Klimley, Thomas V. Agosta, Arnold J. Ammann, Ryan D. Battleson, Matthew D. Pagel, Michael J. Thomas
Publikováno v:
Animal Biotelemetry, Vol 5, Iss 1, Pp 1-15 (2017)
Abstract Background Currently acoustic tag-detecting autonomous receivers must be visited periodically to download the files of tag detections. Hence, the information about the whereabouts of tagged fishes is not available to make prompt regulatory d
Externí odkaz:
https://doaj.org/article/12c3d833bae0449ca6bbb82fba629dea
Autor:
Jeremiah W. Sanders, Justin R. Fletcher, Steven J. Frank, Ho-Ling Liu, Jason M. Johnson, Zijian Zhou, Henry Szu-Meng Chen, Aradhana M. Venkatesan, Rajat J. Kudchadker, Mark D. Pagel, Jingfei Ma
Publikováno v:
SoftwareX, Vol 10, Iss , Pp - (2019)
Herein we introduce a deep learning (DL) application engine (DLAE) system concept, present potential uses of it, and describe pathways for its integration in clinical workflows. An open-source software application was developed to provide a code-free
Externí odkaz:
https://doaj.org/article/e6f24710d2ba43f0994a632d08a24f1e