Zobrazeno 1 - 10
of 1 145
pro vyhledávání: '"D, O'Leary"'
Publikováno v:
eLife, Vol 12 (2024)
Memories are stored as ensembles of engram neurons and their successful recall involves the reactivation of these cellular networks. However, significant gaps remain in connecting these cell ensembles with the process of forgetting. Here, we utilized
Externí odkaz:
https://doaj.org/article/aec38b79b4be4abe8dc61034e34123e6
Autor:
Stephen A Klassen, Jesica Jabbar, Jenna Osborne, Nathaniel J Iannarelli, Emerson S Kirby, Deborah D O'Leary, Sean Locke
Publikováno v:
JMIR Formative Research, Vol 8, p e56921 (2024)
BackgroundPulse interval is a biomarker of psychological and physiological health. Pulse interval can now be assessed using mobile phone apps, which expands researchers’ ability to assess pulse interval in the real world. Prior to implementation, m
Externí odkaz:
https://doaj.org/article/f6d8f11a5ab44f82b6648bf7fc05e5c1
Publikováno v:
Antibiotics, Vol 13, Iss 10, p 956 (2024)
Background/Objectives: Research-engaged academic institutions offer the opportunity to couple undergraduate education/citizen science projects with antimicrobial biodiscovery research. Several initiatives reflecting this ethos have been reported inte
Externí odkaz:
https://doaj.org/article/384ab8db98c54190acdc1ff37fe3e440
Autor:
P. Naik, D. O’Leary
Publikováno v:
European Psychiatry, Vol 67, Pp S178-S179 (2024)
Introduction Psychiatryai.com was launched in 2021 and initial findings were published at EPA 2023. The portal is an advanced computing science project in Applied Data Science and Evidence-Based Healthcare for my MSc studies at the University of Oxfo
Externí odkaz:
https://doaj.org/article/641c51d9cfb1492083fb0b39a4aa823e
Autor:
Pazhanichamy Kalailingam, Khalilatul‐Hanisah Mohd‐Kahliab, SoFong Cam Ngan, Ranjith Iyappan, Evelin Melekh, Tian Lu, Gan Wei Zien, Bhargy Sharma, Tiannan Guo, Adam J MacNeil, Rebecca EK MacPherson, Evangelia Litsa Tsiani, Deborah D O'Leary, Kah Leong Lim, I Hsin Su, Yong‐Gui Gao, A Mark Richards, Raj N Kalaria, Christopher P Chen, Neil E McCarthy, Siu Kwan Sze
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-16 (2023)
Abstract Aging results from the accumulation of molecular damage that impairs normal biochemical processes. We previously reported that age‐linked damage to amino acid sequence NGR (Asn‐Gly‐Arg) results in “gain‐of‐function” conformatio
Externí odkaz:
https://doaj.org/article/0e78e068254840989c041da6a4477442
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112999- (2023)
Summary: Long-term memories are stored as configurations of neuronal ensembles, termed engrams. Although investigation of engram cell properties and functionality in memory recall has been extensive, less is known about how engram cells are affected
Externí odkaz:
https://doaj.org/article/326d975891ee4b888bd1c0371f1a5ef2
Autor:
Meri Ayurini, Peter G. Chandler, Paul D. O’Leary, Ruoxin Wang, David Rudd, Karen D. Milewska, Lara R. Malins, Ashley M. Buckle, Joel F. Hooper
Publikováno v:
JACS Au, Vol 2, Iss 1, Pp 169-177 (2021)
Externí odkaz:
https://doaj.org/article/7f4e2ae5adc84abcaeebf8fe0320de15
Autor:
Nathaniel J. Iannarelli, Terrance J. Wade, Kylie S. Dempster, Jessy Moore, Adam J. MacNeil, Deborah D. O'Leary
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 21 (2022)
Background Adverse childhood experiences (ACEs) have been linked to increased cardiovascular disease (CVD) risk. Previous reports have suggested that accelerated biological aging—indexed by telomere length (TL) and mitochondrial DNA copy number (mt
Externí odkaz:
https://doaj.org/article/cf54d53053f44890a80f4fdaca1a1a97
Autor:
Kingston E. Wong, Terrance J. Wade, Jessy Moore, Ashley Marcellus, Danielle S. Molnar, Deborah D. O'Leary, Adam J. MacNeil
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 25, Iss , Pp 100516- (2022)
Adverse childhood experiences (ACEs) are associated with dysregulation of inflammation and cortisol. The objectives of this study were to use principal component analysis to explore the inflammatory biomarker data to create inflammation composite var
Externí odkaz:
https://doaj.org/article/15c9958434d449fda355a07b86e9f9b7
Autor:
L. Ma, G. C. Hurtt, L. P. Chini, R. Sahajpal, J. Pongratz, S. Frolking, E. Stehfest, K. Klein Goldewijk, D. O'Leary, J. C. Doelman
Publikováno v:
Geoscientific Model Development, Vol 13, Pp 3203-3220 (2020)
Anthropogenic land-use and land-cover change activities play a critical role in Earth system dynamics through significant alterations to biogeophysical and biogeochemical properties at local to global scales. To quantify the magnitude of these impact
Externí odkaz:
https://doaj.org/article/87514ef4f3744372a54dc9311dd0b228