Zobrazeno 1 - 10
of 200
pro vyhledávání: '"D, Nicholl"'
Autor:
Bright Shi, Tsutomu Matsui, Shuo Qian, Thomas M. Weiss, Iain D. Nicholl, David J.E. Callaway, Zimei Bu
Publikováno v:
Biophysical Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc585141ced3d46101827f4dd07225b
https://doi.org/10.1016/j.bpj.2023.04.026
https://doi.org/10.1016/j.bpj.2023.04.026
Autor:
Andreue Devitt, Rajagopal Sharada Kilari, Christopher J. Perry, Stephen T. Safrany, Iain D. Nicholl, Asma’u I.J. Bashir
Publikováno v:
Current Clinical Pharmacology
Background:Oesophageal cancer (OC) is a deadly cancer because of its aggressive nature with survival rates that have barely improved in decades. Epidemiologic studies have shown that low-dose daily intake of aspirin can decrease the incidence of OC.M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c118dd1227a603b25baf3c59dd505216
https://doi.org/10.2174/1574884713666181112141151
https://doi.org/10.2174/1574884713666181112141151
Autor:
Thomas Walz, Christopher B. Stanley, Thomas M. Weiss, Tsutomu Matsui, Zimei Bu, Shuo Qian, William T. Heller, Bashir M. Alhanshali, Martin Bush, Iain D. Nicholl, David J.E. Callaway
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Adherens junctions are specialized cell–cell adhesion complexes found in epithelial, endothelial, and neuronal tissues of multicellular organism. The cadherin–catenin complex is the core component of the adherens junction and transmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968a85a86b9c8654a772d6cd527c1285
https://doi.org/10.1073/pnas.1911489116
https://doi.org/10.1073/pnas.1911489116
Publikováno v:
Proc Natl Acad Sci U S A
As the core component of the adherens junction in cell–cell adhesion, the cadherin–catenin complex transduces mechanical tension between neighboring cells. Structural studies have shown that the cadherin–catenin complex exists as an ensemble of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace6a5c67055742c23013a1962f5ba86
https://doi.org/10.1073/pnas.2025012118
https://doi.org/10.1073/pnas.2025012118
Publikováno v:
Journal of Pharmacy & Bioresources; Vol 16, No 2 (2019); 195-204
Studies show aspirin, a non-steroidal anti-inflammatory drug (NSAID) has potential to decrease incidence of, or mortality from a number of cancers including colorectal cancer (CRC). With emphasis on the treatment of CRC involving platinum compounds,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede9537bc36027b946c3a5914ea3d9fe
https://www.ajol.info/index.php/jpb/article/view/191062
https://www.ajol.info/index.php/jpb/article/view/191062
Autor:
Chandras S. Kankipati, Robert Newman, Stephen T. Safrany, Sarah Jones, Christopher J. Perry, Asma’u I.J. Bashir, Iain D. Nicholl
Publikováno v:
International Journal of Oncology
Epidemiological studies indicate that long-term aspirin usage reduces the incidence of colorectal cancer (CRC) and may protect against other non-CRC associated adenocarcinomas, including oesophageal cancer. A number of hypotheses have been proposed w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8907d3a67c9e5e9fe4685cf72064ba8
https://doi.org/10.3892/ijo.2019.4701
https://doi.org/10.3892/ijo.2019.4701
Autor:
Aoife Kenny, N. Cross, D. Meates, D. Nicholl, T J Cawood, E. Saunders, Richard Laing, C. Drennan
Publikováno v:
Internal Medicine Journal. 46:840-845
We were tasked with creating best possible non-clinical workspace solutions for approximately 450 hospital staff across 11 departments encompassing medical, nursing, allied health, administrative and other support staff. We used a Human-Centred Desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96832e3c68ee82123ae9965013056440
https://doi.org/10.1111/imj.13124
https://doi.org/10.1111/imj.13124
Autor:
Thomas M. Weiss, Christopher B. Stanley, Zimei Bu, Iain D. Nicholl, David J.E. Callaway, Anne L. Martel, Tsutomu Matsui, Bela Farago, William T. Heller
Publikováno v:
Biophysical journal. 115(4)
As a core component of the adherens junction, α-catenin stabilizes the cadherin/catenin complexes to the actin cytoskeleton for the mechanical coupling of cell-cell adhesion. α-catenin also modulates actin dynamics, cell polarity, and cell-migratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b9083fa5dc108ff17e1d52a6724865
https://pubmed.ncbi.nlm.nih.gov/30037495
https://pubmed.ncbi.nlm.nih.gov/30037495
Autor:
Weiguang Wang, Iain D. Nicholl, Malgorzata Trela, Kate Butcher, Kesley Attridge, Vinodh Kannappan
Publikováno v:
Cancer Immunology, Immunotherapy
IL-21 is known to promote anti-tumour immunity due to its ability to promote T cell responses and counteract Treg-mediated suppression. It has also been shown to limit Treg frequencies during tumour-antigen stimulations. However, whether this represe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19444ac96640658cd870262351159540
https://publications.aston.ac.uk/id/eprint/30088/1/Cancer_Immunol_Immunother_2017_Kannappan.pdf
https://publications.aston.ac.uk/id/eprint/30088/1/Cancer_Immunol_Immunother_2017_Kannappan.pdf
Autor:
Steven T. Russell, Christopher J. Perry, Lesley A. Stark, Iain D. Nicholl, Ann-Katrin Claudius, Kerry Guest, Chandra S. Kankipati, Rajagopal Sharada Kilari, Sadiya Hassan
Publikováno v:
Oncology Reports. 32:1670-1680
Substantial evidence indicates that aspirin and related non-steroidal anti-inflammatory drugs (NSAIDs) have potential as chemopreventative/therapeutic agents. However, these agents cannot be universally recommended for prevention purposes due to thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8599f2cb41f27b78fd2adc8e5d35a650
https://doi.org/10.3892/or.2014.3373
https://doi.org/10.3892/or.2014.3373