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Akademický článek

A Next-Generation Adenoviral Vaccine Elicits Mucosal and Systemic Immunogenicity and Reduces Viral Shedding after SARS-CoV-2 Challenge in Nonhuman Primates

Autor: Sarah N. Tedjakusuma, Colin A. Lester, Elena D. Neuhaus, Emery G. Dora, Samanta Gutierrez, Molly R. Braun, Sean N. Tucker, Becca A. Flitter

Publikováno v: Vaccines, Vol 12, Iss 2, p 132 (2024)

As new SARS-CoV-2 variants continue to emerge and impact communities worldwide, next-generation vaccines that enhance protective mucosal immunity may have a significant impact on productive infection and transmission. We have developed recombinant no

Externí odkaz: https://doaj.org/article/ecac1522101542b4941be4df1178c00a

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Akademický článek

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Akademický článek

Stability of Mina v2 for Robot-Assisted Balance and Locomotion

Autor: Carlotta Mummolo, William Z. Peng, Shlok Agarwal, Robert Griffin, Peter D. Neuhaus, Joo H. Kim

Publikováno v: Frontiers in Neurorobotics, Vol 12 (2018)

The assessment of the risk of falling during robot-assisted locomotion is critical for gait control and operator safety, but has not yet been addressed through a systematic and quantitative approach. In this study, the balance stability of Mina v2, a

Externí odkaz: https://doaj.org/article/3b594acbc8ba432aa922c187d9699c6c

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Adenoviral-Based Vaccine Elicits Robust Systemic and Mucosal Cross-Reactive Responses in African Green Monkeys and Reduces Shedding after SARS-CoV-2 Challenge

Autor: Sarah N. Tedjakusuma, Colin A. Lester, Elena D. Neuhaus, Emery G. Dora, Sean N. Tucker, Becca A. Flitter

As new SARS-CoV-2 variants continue to emerge and impact communities worldwide, efforts to develop next generation vaccines that enhance mucosal immunity would be beneficial for protecting individuals and reducing community transmission. We have deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed8a10d0d2c0b043870b9c6528b351c1
https://doi.org/10.1101/2022.12.19.521127

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1960. Mucosal rAd5 Immunization against SARS-CoV-2 Spike Elicits Cross-Reactive Nasal and Serum Neutralizing Antibodies and Protects Against Beta Variant Challenge in African Green Monkeys

Autor: Becca A Flitter, Sarah N Tedjakusuma, Colin A Lester, Elena D Neuhaus, Susan Johnson, Emery G Dora, Nadine Peinovich, Clara B Jegede, Sean N Tucker

Publikováno v: Open Forum Infectious Diseases. 9

Background Mucosal vaccination may offer increased protection against SARS-CoV-2 compared to parental immunization. Here, we describe immunogenicity and efficacy following viral challenge in non-human primates after intranasal delivery of three uniqu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22477dedec4696579f94f12870bfad9c
https://doi.org/10.1093/ofid/ofac492.1586

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Akademický článek

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Akademický článek

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Gold‐Catalyzed Cycloisomerization of Sulfur Ylides to Dihydrobenzothiepines

Autor: Rafael Gomes, Thomas Alexander Stephens, Iakovos Saridakis, Nuno Maulide, Rik Oost, Christian Knittl-Frank, Alberto Oppedisano, Antonio Misale, James D. Neuhaus

Publikováno v: Chemistry (Weinheim an Der Bergstrasse, Germany)

The metal‐promoted nucleophilic addition of sulfur ylides to π‐systems is a well‐established reactivity. However, the driving force of such transformations, elimination of a sulfide moiety, entails stoichiometric byproducts making them unfavor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51534488052de332ad013977d670cd7c
http://europepmc.org/articles/PMC7496544

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Mucosal Immunization of Cynomolgus Macaques with Adenoviral Vector Vaccine Elicits Neutralizing Nasal and Serum Antibody to Several SARS-CoV-2 Variants

Autor: Becca A. Flitter, Colin A. Lester, Sarah N. Tedjakusuma, Emery G. Dora, Nadine Peinovich, Mario Cortese, Clarissa I. Martinez, Clara B. Jegede, Elena D. Neuhaus, Sean N. Tucker

The emergence of SARS-CoV-2 variants continues to be a major obstacle for controlling the global pandemic. Despite the currently authorized SARS-CoV-2 vaccines ability to reduce severe disease and hospitalization, new immunization strategies are need

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97d35d9a88481f92a219e10f3873380e
https://doi.org/10.1101/2022.02.21.481345

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Patient- and Physician-Reported Outcome of Combined Fractional CO2 and Pulse Dye Laser Treatment for Hypertrophic Scars in Children

Autor: Kathrin Neuhaus, Julia Elrod, Clemens Schiestl, D. Neuhaus, Christoph Mohr

Publikováno v: Annals of plastic surgery. 85(3)

Background Hypertrophic scars are commonly seen in children and associated with pruritus, pain, functional impairment, and aesthetic disfigurement. Ablative fractional CO2 and pulse dye laser are emerging techniques to improve scar quality. Only limi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e46a673aaf22c8ff6134621ebd72751
https://pubmed.ncbi.nlm.nih.gov/32349082

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