Zobrazeno 1 - 10
of 300
pro vyhledávání: '"D, Mul"'
Autor:
R. D. M. Varkevisser, A. Cecil, C. Prehn, D. Mul, H. J. Aanstoot, A. D. Paterson, B. H. R. Wolffenbuttel, M. M. van der Klauw
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study investigates impaired awareness of hypoglycaemia (IAH), a complication of insulin therapy affecting 20–40% of individuals with type 1 diabetes. The exact pathophysiology is unclear, therefore we sought to identify metabolic sign
Externí odkaz:
https://doaj.org/article/fe07f1cc4d12473ab279f90bdd5b5bf4
Autor:
Ayano Shiba, Paul de Goede, Roberta Tandari, Ewout Foppen, Nikita L. Korpel, Tom V. Coopmans, Tom P. Hellings, Merel W. Jansen, Annelou Ruitenberg, Wayne I.G.R. Ritsema, Chun-Xia Yi, Joram D. Mul, Dirk Jan Stenvers, Andries Kalsbeek
Publikováno v:
Neurobiology of Sleep and Circadian Rhythms, Vol 17, Iss , Pp 100106- (2024)
Circadian disruption is an important factor driving the current-day high prevalence of obesity and type-2 diabetes. While the impact of incorrect timing of caloric intake on circadian disruption is widely acknowlegded, the contribution of incorrect t
Externí odkaz:
https://doaj.org/article/9a4fa1a71a80496e91051ba32f866208
Autor:
Amber Koert, Annemie Ploeger, Claudi L.H. Bockting, Mathias V. Schmidt, Paul J. Lucassen, Anouk Schrantee, Joram D. Mul
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100410- (2021)
Background: Social stress is an important environmental risk factor for the development of psychiatric disorders, including depression and anxiety disorders. Social stress paradigms are commonly used in rats and mice to gain insight into the pathogen
Externí odkaz:
https://doaj.org/article/234cc0ae0aa9464296e532aa24a8b271
Autor:
Ashley M. Shemery, Meredith Zendlo, Jesse Kowalski, Erin Gorrell, Scott Everett, Jacob G. Wagner, Ashley E. Davis, Lauren G. Koch, Steven L. Britton, Joram D. Mul, Colleen M. Novak
Publikováno v:
Temperature. :1-15
Autor:
Müzeyyen Ugur, Isabel Pieterse, Gideon F. Meerhoff, Leslie Eggels, Khalid Lamuadni, Unga A. Unmehopa, Jan Booij, Susanne E. la Fleur, Joram D. Mul
Publikováno v:
Ugur, M Z, Pieterse, I, Meerhoff, G F, Eggels, L, Lamuadni, K, Unmehopa, U A, Booij, J, la Fleur, S E & Mul, J D 2023, ' Voluntary physical activity modulates self-selection of a high-caloric choice diet in male Wistar rats ', Physiology and Behavior, vol. 268, 114239 . https://doi.org/10.1016/j.physbeh.2023.114239
Physiology and Behavior, 268:114239. Elsevier Inc.
Physiology & behavior, 268:114239. Elsevier Inc.
Physiology & Behavior, 268. Elsevier B.V.
Physiology and Behavior, 268:114239. Elsevier Inc.
Physiology & behavior, 268:114239. Elsevier Inc.
Physiology & Behavior, 268. Elsevier B.V.
Physical exercise training has been positioned as a behavioral strategy to prevent or alleviate obesity via promotion of energy expenditure as well as modulation of energy intake resulting from changes in dietary preference. Brain adaptations underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedeac4b2ef99dc4e823d8304d5158e1
https://research.vumc.nl/en/publications/724ff282-9030-400d-878c-bca7e0a921ce
https://research.vumc.nl/en/publications/724ff282-9030-400d-878c-bca7e0a921ce
Autor:
Ana Barbara Alves-Wagner, Kristin I Stanford, Noah B Prince, Kawai So, Joram D Mul, Ercument Dirice, Michael F Hirshman, Rohit N Kulkarni, Laurie J Goodyear
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
ObjectivePoor maternal and paternal environments increase the risk for obesity and diabetes in offspring, whereas maternal and paternal exercise in mice can improve offspring metabolic health. We determined the effects of combined maternal and patern
Externí odkaz:
https://doaj.org/article/5e83270f70b5476c882a997a57346fc1
Background: Cardiovascular disease (CVD) is a precarious complication of type 1 diabetes (T1D). Alongside glycaemic control, lipid and blood pressure (BP) management are essential for the prevention of CVD. However, age-specific differences in lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0245a72f6af2080342f6f23d2666325b
https://doi.org/10.21203/rs.3.rs-2442331/v1
https://doi.org/10.21203/rs.3.rs-2442331/v1
Autor:
Silvana Obici, I. Jack Magrisso, Armen S. Ghazarian, Alireza Shirazian, Jonas R. Miller, Christine M. Loyd, Denovan P. Begg, Kimberly A. Krawczewski Carhuatanta, Michael K. Haas, Jon F. Davis, Stephen C. Woods, Darleen A. Sandoval, Randy J. Seeley, Laurie J. Goodyear, Emmanuel N. Pothos, Joram D. Mul
Publikováno v:
Molecular Metabolism, Vol 4, Iss 10, Pp 692-705 (2015)
Objective: Melanocortin-4 receptors (MC4Rs) are highly expressed by dopamine-secreting neurons of the mesolimbic tract, but their functional role has not been fully resolved. Voluntary wheel running (VWR) induces adaptations in the mesolimbic dopamin
Externí odkaz:
https://doaj.org/article/4c660839e71d4506b3fc5729cebc1ffc
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Glucose-sensing neurons are neurons that alter their activity in response to changes in extracellular glucose. These neurons, which are an important mechanism the brain uses to monitor changes in glycaemia, are present in the hypothalamus, where they
Externí odkaz:
https://doaj.org/article/60d6464376304bdbad18f5494a9c1758
Autor:
Paul J. Lucassen, Kate Jeffrey, Antonis Asiminas, Heidi M. B. Lesscher, Jos Prickaerts, Gertjan van Dijk, Amanda J. Kiliaan, Daniela Jezova, Carlos P. Fitzsimons, Klaus-Peter Lesch, S. Mechiel Korte, Ulrich L. M. Eisel, Roger A.H. Adan, Tamas Kozicz, Liset Menendez de la Prida, Joanes Grandjean, Marloes J. A. G. Henckens, Corette J. Wierenga, Vladyslav V. Vyazovskiy, Cyriel M. A. Pennartz, Marten P. Smidt, Ype Elgersma, Anne S. Mallien, Sharon M. Kolk, Liya Ma, Kirk Leech, Ingo Willuhn, Jorge F. Mejias, Maximilian Wiesmann, Frank J. Meye, Louk J. M. J. Vanderschuren, Marilise Escobar Burger, Sidarta Ribeiro, August B. Smit, Peter Meerlo, Robbert Havekes, Eddy A. van der Zee, Rixt van der Veen, Regien G. Schoemaker, Massimo Pasqualetti, Andries Kalsbeek, Martien J H Kas, Michael Bader, Joram D. Mul, Bernhard Englitz, Janine I. Rossato, Denovan P. Begg, Tomonori Takeuchi, Markus Wöhr, Antonio Fernández-Ruiz, Bella Williams, Nael Nadif Kasri, Aniko Korosi, Judith R. Homberg, Tom Beckers, Maarten Kamermans, Piotr Popik, Peter Gass, Umberto Olcese, Anna S. Mitchell, Christiane Herden, Jocelien D A Olivier, Monique Wolvekamp, Arjan Blokland, Azahara Oliva González, Natalia Alenina, Lisa Genzel, Wendy Jarrett, Ali-Akbar Salari, Roelof A. Hut, Anne-Marie van Dam, Anita Lüthi, Benno Roozendaal, Steven A. Kushner
Publikováno v:
Neuron, 109(15), 2374-2379. Cell Press
Neuron, 109(15), 2374. Cell Press
Neuron, 109, 15, pp. 2374-2379
Neuron, 109, 2374-2379
Homberg, J R, Adan, R A H, Alenina, N, Asiminas, A, Bader, M, Beckers, T, Begg, D P, Blokland, A, Burger, M E, van Dijk, G, Eisel, U L M, Elgersma, Y, Englitz, B, Fernandez-Ruiz, A, Fitzsimons, C P, van Dam, A M, Gass, P, Grandjean, J, Havekes, R, Henckens, M J A G, Herden, C, Hut, R A, Jarrett, W, Jeffrey, K, Jezova, D, Kalsbeek, A, Kamermans, M, Kas, M J, Kasri, N N, Kiliaan, A J, Kolk, S M, Korosi, A, Korte, S M, Kozicz, T, Kushner, S A, Leech, K, Lesch, K P, Lesscher, H, Lucassen, P J, Luthi, A, Ma, L, Mallien, A S, Meerlo, P, Mejias, J F, Meye, F J, Mitchell, A S, Mul, J D, Olcese, U, González, A O, Olivier, J D A, Pasqualetti, M, Pennartz, C M A, Popik, P, Prickaerts, J, de la Prida, L M, Ribeiro, S, Roozendaal, B, Rossato, J I, Salari, A A, Schoemaker, R G, Smit, A B, Vanderschuren, L J M J, Takeuchi, T, van der Veen, R, Smidt, M P, Vyazovskiy, V V, Wiesmann, M, Wierenga, C J, Williams, B, Willuhn, I, Wöhr, M, Wolvekamp, M, van der Zee, E A & Genzel, L 2021, ' The continued need for animals to advance brain research ', Neuron, vol. 109, no. 15, pp. 2374-2379 . https://doi.org/10.1016/j.neuron.2021.07.015
Homberg, J R, Adan, R A H, Alenina, N, Asiminas, A, Bader, M, Beckers, T, Begg, D P, Blokland, A, Burger, M E, van Dijk, G, Eisel, U L M, Elgersma, Y, Englitz, B, Fernandez-Ruiz, A, Fitzsimons, C P, van Dam, A-M, Gass, P, Grandjean, J, Havekes, R, Henckens, M J A G, Herden, C, Hut, R A, Jarrett, W, Jeffrey, K, Jezova, D, Kalsbeek, A, Kamermans, M, Kas, M J, Kasri, N N, Kiliaan, A J, Kolk, S M, Korosi, A, Korte, S M, Kozicz, T, Kushner, S A, Leech, K, Lesch, K-P, Lesscher, H, Lucassen, P J, Luthi, A, Ma, L, Mallien, A S, Meerlo, P, Mejias, J F, Meye, F J, Mitchell, A S, Mul, J D, Olcese, U, González, A O, Olivier, J D A, Pasqualetti, M, Pennartz, C M A, Popik, P, Prickaerts, J, de la Prida, L M, Ribeiro, S, Roozendaal, B, Rossato, J I, Salari, A-A, Schoemaker, R G, Smit, A B, Vanderschuren, L J M J, Takeuchi, T, van der Veen, R, Smidt, M P, Vyazovskiy, V V, Wiesmann, M, Wierenga, C J, Williams, B, Willuhn, I, Wöhr, M, Wolvekamp, M, van der Zee, E A & Genzel, L 2021, ' The continued need for animals to advance brain research ', Neuron, vol. 109, no. 15, pp. 2374-2379 . https://doi.org/10.1016/j.neuron.2021.07.015
Neuron, 109(15), 2374-2379. CELL PRESS
Digital.CSIC. Repositorio Institucional del CSIC
instname
Neuron, 109(15), 2374. Cell Press
Neuron, 109, 15, pp. 2374-2379
Neuron, 109, 2374-2379
Homberg, J R, Adan, R A H, Alenina, N, Asiminas, A, Bader, M, Beckers, T, Begg, D P, Blokland, A, Burger, M E, van Dijk, G, Eisel, U L M, Elgersma, Y, Englitz, B, Fernandez-Ruiz, A, Fitzsimons, C P, van Dam, A M, Gass, P, Grandjean, J, Havekes, R, Henckens, M J A G, Herden, C, Hut, R A, Jarrett, W, Jeffrey, K, Jezova, D, Kalsbeek, A, Kamermans, M, Kas, M J, Kasri, N N, Kiliaan, A J, Kolk, S M, Korosi, A, Korte, S M, Kozicz, T, Kushner, S A, Leech, K, Lesch, K P, Lesscher, H, Lucassen, P J, Luthi, A, Ma, L, Mallien, A S, Meerlo, P, Mejias, J F, Meye, F J, Mitchell, A S, Mul, J D, Olcese, U, González, A O, Olivier, J D A, Pasqualetti, M, Pennartz, C M A, Popik, P, Prickaerts, J, de la Prida, L M, Ribeiro, S, Roozendaal, B, Rossato, J I, Salari, A A, Schoemaker, R G, Smit, A B, Vanderschuren, L J M J, Takeuchi, T, van der Veen, R, Smidt, M P, Vyazovskiy, V V, Wiesmann, M, Wierenga, C J, Williams, B, Willuhn, I, Wöhr, M, Wolvekamp, M, van der Zee, E A & Genzel, L 2021, ' The continued need for animals to advance brain research ', Neuron, vol. 109, no. 15, pp. 2374-2379 . https://doi.org/10.1016/j.neuron.2021.07.015
Homberg, J R, Adan, R A H, Alenina, N, Asiminas, A, Bader, M, Beckers, T, Begg, D P, Blokland, A, Burger, M E, van Dijk, G, Eisel, U L M, Elgersma, Y, Englitz, B, Fernandez-Ruiz, A, Fitzsimons, C P, van Dam, A-M, Gass, P, Grandjean, J, Havekes, R, Henckens, M J A G, Herden, C, Hut, R A, Jarrett, W, Jeffrey, K, Jezova, D, Kalsbeek, A, Kamermans, M, Kas, M J, Kasri, N N, Kiliaan, A J, Kolk, S M, Korosi, A, Korte, S M, Kozicz, T, Kushner, S A, Leech, K, Lesch, K-P, Lesscher, H, Lucassen, P J, Luthi, A, Ma, L, Mallien, A S, Meerlo, P, Mejias, J F, Meye, F J, Mitchell, A S, Mul, J D, Olcese, U, González, A O, Olivier, J D A, Pasqualetti, M, Pennartz, C M A, Popik, P, Prickaerts, J, de la Prida, L M, Ribeiro, S, Roozendaal, B, Rossato, J I, Salari, A-A, Schoemaker, R G, Smit, A B, Vanderschuren, L J M J, Takeuchi, T, van der Veen, R, Smidt, M P, Vyazovskiy, V V, Wiesmann, M, Wierenga, C J, Williams, B, Willuhn, I, Wöhr, M, Wolvekamp, M, van der Zee, E A & Genzel, L 2021, ' The continued need for animals to advance brain research ', Neuron, vol. 109, no. 15, pp. 2374-2379 . https://doi.org/10.1016/j.neuron.2021.07.015
Neuron, 109(15), 2374-2379. CELL PRESS
Digital.CSIC. Repositorio Institucional del CSIC
instname
Policymakers aim to move toward animal-free alternatives for scientific research and have introduced very strict regulations for animal research. We argue that, for neuroscience research, until viable and translational alternatives become available a