Zobrazeno 1 - 10
of 422
pro vyhledávání: '"D, Morrell"'
Publikováno v:
Cogent Education, Vol 11, Iss 1 (2024)
In the early 2000s, Indonesia’s shift from teacher education institutes to universities brought about a profound change in the role of Teacher Educators (TEs), making their environment more research-focused. This exploratory study examines science
Externí odkaz:
https://doaj.org/article/ed9e148479d64b889de533ae2bdb7a71
Autor:
Vikramjit Mukherjee, MD, FRCP, Radu Postelnicu, MD, Chelsie Parker, MS, Patrick S. Rivers, PhD, George L. Anesi, MD, MSCE, MBE, Adair Andrews, RN, MATD, Erin Ables, MA, Eric D. Morrell, MD, MA, David M. Brett-Major, MD, MPH, M. Jana Broadhurst, MD, PhD, J. Perren Cobb, MD, Amy Irwin, DNP, RN, Christopher J. Kratochvil, MD, Kelsey Krolikowski, BA, Vishakha K. Kumar, MD, MBA, Douglas P. Landsittel, PhD, Richard A. Lee, MD, Janice M. Liebler, MD, Leopoldo N. Segal, MD, Jonathan E. Sevransky, MD, MHS, Avantika Srivastava, MS, Timothy M. Uyeki, MD, MPH, Mark M. Wurfel, MD, PhD, David Wyles, MD, Laura E. Evans, MD, MSc, Karen Lutrick, PhD, Pavan K. Bhatraju, MD, MSc, on behalf of the Severe Acute Respiratory Infection-Preparedness (SARI-PREP) Study Group
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1122 (2024)
IMPORTANCE:. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has evolved through multiple phases in the United States, with significant differences in patient centered outcomes with improvements in hospital strain, medical c
Externí odkaz:
https://doaj.org/article/40d4a8c263284e60ad1b0d3e293f20b0
Autor:
Eric D. Morrell, Sarah E. Holton, Matthew Lawrance, Marika Orlov, Zoie Franklin, Mallorie A. Mitchem, Hannah DeBerg, Vivian H. Gersuk, Ashley Garay, Elizabeth Barnes, Ted Liu, Ithan D. Peltan, Angela Rogers, Steven Ziegler, Mark M. Wurfel, Carmen Mikacenic
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The transcriptional and phenotypic characteristics that define alveolar monocyte and macrophage subsets in acute hypoxemic respiratory failure (AHRF) are poorly understood. Here, we apply CITE-seq (single-cell RNA-sequencing and cell-surface
Externí odkaz:
https://doaj.org/article/ca5df4760dd1458e9a4f62c4a15084fa
Autor:
Neha A. Sathe, Su Xian, F. Linzee Mabrey, David R. Crosslin, Sean D. Mooney, Eric D. Morrell, Kevin Lybarger, Meliha Yetisgen, Gail P. Jarvik, Pavan K. Bhatraju, Mark M. Wurfel
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Evolving ARDS epidemiology and management during COVID-19 have prompted calls to reexamine the construct validity of Berlin criteria, which have been rarely evaluated in real-world data. We developed a Berlin ARDS definition (EHR-
Externí odkaz:
https://doaj.org/article/fa88bb75be1c42fa943455768a04a123
Autor:
Sarah E Holton, Mallorie Mitchem, Hamid Chalian, Sudhakar Pipavath, Eric D Morrell, Pavan K Bhatraju, Jessica A Hamerman, Cate Speake, Uma Malhotra, Mark M Wurfel, Steven E Ziegler, Carmen Mikacenic
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0285638 (2024)
Acute respiratory distress syndrome (ARDS) has a fibroproliferative phase that may be followed by pulmonary fibrosis. Pulmonary fibrosis following COVID-19 pneumonia has been described at autopsy and following lung transplantation. We hypothesized th
Externí odkaz:
https://doaj.org/article/bc9a11fe4f674f569d7165ab02b57dda
Autor:
Runa Kuley, Bhargavi Duvvuri, Jeffrey J. Wallin, Nam Bui, Mary Vic Adona, Nicholas G. O’Connor, Sharon K. Sahi, Ian B. Stanaway, Mark M. Wurfel, Eric D. Morrell, W. Conrad Liles, Pavan K. Bhatraju, Christian Lood
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTNeutrophil dysregulation is well established in COVID-19. However, factors contributing to neutrophil activation in COVID-19 are not clear. We assessed if N-formyl methionine (fMet) contributes to neutrophil activation in COVID-19. Elevated l
Externí odkaz:
https://doaj.org/article/68bb341cfe6c496ea2f3d2dd7b86a2b7
Autor:
Neha A. Sathe, MD, MSc, Ana Mostaghim, MD, Elizabeth Barnes, BS, Nicholas G. O’Connor, BS, Sharon K. Sahi, MS, Sana S. Sakr, PhD, Jana M. Zahlan, BS, Craig H. Smith, MD, Michael Fitzpatrick, BS, Eric D. Morrell, MD, W. Conrad Liles, MD, PhD, Pavan K. Bhatraju, MD, MSc
Publikováno v:
Critical Care Explorations, Vol 5, Iss 7, p e0945 (2023)
IMPORTANCE:. Kidney and lung injury are closely inter-related during acute respiratory illness, but the molecular risk factors that these organ injuries share are not well defined. OBJECTIVES:. We identified plasma biomarkers associated with severe a
Externí odkaz:
https://doaj.org/article/4aa7528dc2fe41138a4f33b228f41845
Autor:
F. Linzee Mabrey, Hui Nian, Chang Yu, Elizabeth M. Barnes, Uma Malhotra, Carmen Mikacenic, Julia Goldstein, D. Shane O'Mahony, Julia Garcia-Diaz, Patricia Finn, Kirk Voelker, Eric D. Morrell, Wesley H. Self, Patrice M. Becker, Thomas R. Martin, Mark M. Wurfel
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104667- (2023)
Summary: Background: Severe COVID-19 is associated with innate immunopathology, and CD14, a proximal activator of innate immunity, has been suggested as a potential therapeutic target. Methods: We conducted the COVID-19 anti-CD14 Treatment Trial (CaT
Externí odkaz:
https://doaj.org/article/e8fbf755cfe945669342f97ba73dd512
Autor:
Benjamin C. N. Proudfoot, Darin A. Ragozzine, Meagan L. Thatcher, Will Grundy, Dallin J. Spencer, Tahina M. Alailima, Sawyer Allen, Penelope C. Bowden, Susanne Byrd, Conner D. Camacho, Gibson H. Campbell, Edison P. Carlisle, Jacob A. Christensen, Noah K. Christensen, Kaelyn Clement, Benjamin J. Derieg, Mara K. Dille, Cristian Dorrett, Abigail L. Ellefson, Taylor S. Fleming, N. J. Freeman, Ethan J. Gibson, William G. Giforos, Jacob A. Guerrette, Olivia Haddock, S. Ashton Hammond, Zachary A. Hampson, Joshua D. Hancock, Madeline S. Harmer, Joseph R. Henderson, Chandler R. Jensen, David Jensen, Ryleigh E. Jensen, Joshua S. Jones, Cameron C. Kubal, Jacob N. Lunt, Stephanie Martins, McKenna Matheson, Dahlia Maxwell, Timothy D. Morrell, McKenna M. Myckowiak, Maia A. Nelsen, Spencer T. Neu, Giovanna G. Nuccitelli, Kayson M. Reardon, Austin S. Reid, Kenneth G. Richards, Megan R. W. Robertson, Tanner D. Rydalch, Conner B. Scoresby, Ryan L. Scott, Zacory D. Shakespear, Elliot A. Silveira, Grace C. Steed, Christiana Z. Suggs, Garrett D. Suggs, Derek M. Tobias, Matthew L. Toole, McKayla L. Townsend, Kade L. Vickers, Collin R. Wagner, Madeline S. Wright, Emma M. A. Zappala
Publikováno v:
The Astronomical Journal, Vol 167, Iss 4, p 144 (2024)
About 40 trans-Neptunian binaries (TNBs) have fully determined orbits with about 10 others being solved except for breaking the mirror ambiguity. Despite decades of study, almost all TNBs have only ever been analyzed with a model that assumes perfect
Externí odkaz:
https://doaj.org/article/75aea1eac48a4e97a40334d313d7bcc5
Autor:
Jennifer H. Madenspacher, Eric D. Morrell, Jeffrey G. McDonald, Bonne M. Thompson, Yue Li, Konstantin G. Birukov, Anna A. Birukova, Renee D. Stapleton, Aidin Alejo, Peer W. Karmaus, Julie M. Meacham, Prashant Rai, Carmen Mikacenic, Mark M. Wurfel, Michael B. Fessler
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Cholesterol-25-hydroxylase (CH25H), the biosynthetic enzyme for 25-hydroxycholesterol (25HC), is most highly expressed in the lung, but its role in lung biology is poorly defined. Recently, we reported that Ch25h is induced in monocyte-derived macrop
Externí odkaz:
https://doaj.org/article/1109a8bf1a3b4286b2173352ad418326