Zobrazeno 1 - 10
of 221
pro vyhledávání: '"D, Monard"'
Publikováno v:
Journal of Neuroscience Research. 42:562-570
The up-regulation of PN-1 following nerve lesion has been investigated in vitro in cultures of dorsal root ganglion (DRG) explants, sciatic nerve segments, and isolated Schwann cells. In the first culture model, Schwann cells associated with neuronal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbc3acfcfe39d240d02096fd2469ab6
https://doi.org/10.1002/jnr.490420414
https://doi.org/10.1002/jnr.490420414
Publikováno v:
The Journal of Neuroscience. 15:750-761
Protease nexin-1 (PN-1) is a potent inhibitor of serine proteases, such as thrombin and plasminogen activators, which is secreted into the extracellular space. Since PN-1 is induced following lesion of the sciatic nerve, the effect of substances know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4a47e6accde93144853d334c0820e2
https://doi.org/10.1523/jneurosci.15-01-00750.1995
https://doi.org/10.1523/jneurosci.15-01-00750.1995
Publikováno v:
Journal of Neuroscience Research. 37:155-168
The serine protease inhibitor and neurite outgrowth promoter glia derived nexin (GDN) is expressed in the rat CNS during embryogenesis and persists in the olfactory system of the adult where receptor neurons are replaced throughout life. We investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20733600c39e74e7a871f2e3cf0a223d
https://doi.org/10.1002/jnr.490370202
https://doi.org/10.1002/jnr.490370202
Publikováno v:
Journal of Neuroscience Research. 37:256-270
Glia-derived nexin/protease nexin-1 (GDN/PN-1) is a serine protease inhibitor that is secreted by glial cells and fibroblasts in culture. In the adult mammalian nervous system it has been shown to be expressed in the olfactory system and by some glia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8df22aa6f07005c3113ab23bf64d0c
https://doi.org/10.1002/jnr.490370211
https://doi.org/10.1002/jnr.490370211
Autor:
P M, Rettenberger, K, Oka, L, Ellgaard, H H, Petersen, A, Christensen, P M, Martensen, D, Monard, M, Etzerodt, L, Chan, P A, Andreasen
Publikováno v:
The Journal of biological chemistry. 274(13)
The very low density lipoprotein receptor (VLDLR) binds, among other ligands, the Mr 40,000 receptor-associated protein (RAP) and a variety of serine proteinase-serpin complexes, including complexes of the proteinase urokinase-type plasminogen activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f79f41a48c80ee3d478c51c2433dbbb8
https://pubmed.ncbi.nlm.nih.gov/10085143
https://pubmed.ncbi.nlm.nih.gov/10085143
Publikováno v:
The European journal of neuroscience. 10(5)
HDs racI Thrombin causes profound metabolic and morphological changes in cultured neural cells via activation of the thrombin receptor, also called protease-activated receptor 1 (PAR1). PAR1 mRNA is present in the rat brain, but the role of this rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0bebf3c22e448455bbb3dab6b24cdd90
https://pubmed.ncbi.nlm.nih.gov/9751132
https://pubmed.ncbi.nlm.nih.gov/9751132
Astrocyte spreading in response to thrombin and lysophosphatidic acid is dependent on the Rho GTPase
Publikováno v:
Glia. 21(2)
Astrocytes are typically star shaped cells playing diverse roles in the function of the nervous system. In astrocyte cultures established from the cerebral hemispheres of newborn rats, the cells have generally a polygonal fibroblast-like morphology,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa3621151cd64e2a98341d07fdeff33a
https://pubmed.ncbi.nlm.nih.gov/9336238
https://pubmed.ncbi.nlm.nih.gov/9336238
Publikováno v:
Maturation Phenomenon in Cerebral Ischemia II ISBN: 9783540616733
The reexpression of a developmentally regulated serine protease inhibitor with high affinity for thrombin, the glia-derived protease nexin-1, was investigated in thirteen autoptic brains with fresh and old infarcts. In adult intact brain, protease ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::908c8ddc8f4ae39c54ff0a40a30082be
https://doi.org/10.1007/978-3-642-60546-8_19
https://doi.org/10.1007/978-3-642-60546-8_19
Publikováno v:
The European journal of neuroscience. 5(3)
The re-expression of the developmentally regulated serine protease inhibitor glia-derived nexin (GDN) was investigated 1 year after transient global ischaemia induced by the four-vessel occlusion technique in rats. The CA1 sector of the hippocampus w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb80ad7b70ac01fb1e7a4245272ec6f7
https://pubmed.ncbi.nlm.nih.gov/8261109
https://pubmed.ncbi.nlm.nih.gov/8261109
Publikováno v:
Gene expression. 3(2)
The first three exons and the promoter of rat glia-derived nexin, also called protease nexin-1 (GDN/PN-1), have been identified through analysis of rat genomic clones. A 1.6 kilobase (kb) fragment containing 105 base pairs of the first exon and 5′-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3704dcb9615a391fc6c7a006742f9a0f
https://pubmed.ncbi.nlm.nih.gov/8268720
https://pubmed.ncbi.nlm.nih.gov/8268720