Zobrazeno 1 - 7
of 7
pro vyhledávání: '"D, Moeurs"'
Publikováno v:
Biotechnology and Bioengineering. 44:753-764
During long-term continuous culture of the hybridoma cell line 11317, a better-producing subclone (I1317-SF11), giving improved productivity, has been selected. The comparison of the original cell line (I1317-DC) with this subclone revealed that alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::771242d4cf6a174450cd7f36a56a0679
https://doi.org/10.1002/bit.260440612
https://doi.org/10.1002/bit.260440612
Publikováno v:
Biotechnology and bioengineering. 44(6)
During long-term continuous culture of the hybridoma cell line 11317, a better-producing subclone (I1317-SF11), giving improved productivity, has been selected. The comparison of the original cell line (I1317-DC) with this subclone revealed that alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36b78cd7e8fa300dd46c5bc7706c2f80
https://pubmed.ncbi.nlm.nih.gov/18618836
https://pubmed.ncbi.nlm.nih.gov/18618836
The objective of this study was to compare the kinetic characteristics of some key components of monoclonal antibody synthesis (growth, cell specific productivity, mRNAs coding for heavy and light chain IgG) in hybridoma continuous cultures in a prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac5e16259569564b474761085f9adcb
https://doi.org/10.1016/b978-0-7506-1845-8.50122-8
https://doi.org/10.1016/b978-0-7506-1845-8.50122-8
The effects of dilution rate (D) on I.13.17. hybridoma growth, metabolism, and antibody production in semi-continuous culture were evaluated. Steady-state data were obtained at six D between 0.008 and 0,055 h-1. Viable cell concentration was maximal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c9006c22debfea07e7300be7867923
https://doi.org/10.1016/b978-0-7506-0421-5.50061-1
https://doi.org/10.1016/b978-0-7506-0421-5.50061-1
Kinetic characteristics of some key components of monoclonal antibody (MAb) synthesis were compared during hybridoma batch and semicontinuous cultures. During batch culture, there was a general trend of decrease in the amounts of total cellular RNA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72dafea958ffbf23d0f35ccd253f7472
https://doi.org/10.1016/b978-0-7506-0421-5.50022-2
https://doi.org/10.1016/b978-0-7506-0421-5.50022-2
The release of lactate dehydrogenase (LDH), alkaline phosphatase (APH), and adenylate kinase (AK) in the culture medium can be used to estimate the dead cell number in cell cultures, whereby satisfactory results have been obtained. Although the cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ed84a074c5bf6bef05b22c77e1f5532
https://doi.org/10.1016/b978-0-7506-0421-5.50079-9
https://doi.org/10.1016/b978-0-7506-0421-5.50079-9
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