Zobrazeno 1 - 10
of 479
pro vyhledávání: '"D, McLellan"'
Autor:
Xiuli Zhang, S. Peter Goedegebuure, Michael Y. Chen, Rashmi Mishra, Felicia Zhang, Yik Yeung Yu, Kartik Singhal, Lijin Li, Feng Gao, Nancy B. Myers, Tammi Vickery, Jasreet Hundal, Michael D. McLellan, Mark A. Sturmoski, Samuel W. Kim, Ina Chen, Jesse T. Davidson, Narendra V. Sankpal, Stephanie Myles, Rama Suresh, Cynthia X. Ma, Ademuyiwa Foluso, Andrea Wang-Gillam, Sherri Davies, Ian S. Hagemann, Elaine R. Mardis, Obi Griffith, Malachi Griffith, Christopher A. Miller, Ted H. Hansen, Timothy P. Fleming, Robert D. Schreiber, William E. Gillanders
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Neoantigen vaccines can induce or enhance highly specific antitumor immune responses with minimal risk of autoimmunity. We have developed a neoantigen DNA vaccine platform capable of efficiently presenting both HLA class I and II
Externí odkaz:
https://doaj.org/article/361f87535f3347da8e2cfda87d75ab59
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract Non-synonymous mutations in the SARS-CoV-2 spike region affect cell entry, tropism, and immune evasion, while frequent synonymous mutations may modify viral fitness. Host microRNAs, a type of non-coding RNA, play a crucial role in the viral
Externí odkaz:
https://doaj.org/article/d71ca0c683844e0c8fb626685445bdfb
Autor:
Dhammika Leshan Wannigama, Mohan Amarasiri, Parichart Hongsing, Cameron Hurst, Charin Modchang, Sudarat Chadsuthi, Suparinthon Anupong, Phatthranit Phattharapornjaroen, Ali Hosseini Rad S. M., Stefan Fernandez, Angkana T. Huang, Porames Vatanaprasan, Dylan John Jay, Thammakorn Saethang, Sirirat Luk-in, Robin James Storer, Puey Ounjai, Naveen Kumar Devanga Ragupathi, Phitsanuruk Kanthawee, Daisuke Sano, Takashi Furukawa, Kazunari Sei, Asada Leelahavanichkul, Talerngsak Kanjanabuch, Nattiya Hirankarn, Paul G. Higgins, Anthony Kicic, Andrew C. Singer, Tanittha Chatsuwan, Sam Trowsdale, Shuichi Abe, Alexander D. McLellan, Hitoshi Ishikawa
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107019- (2023)
Summary: Equitable SARS-CoV-2 surveillance in low-resource communities lacking centralized sewers is critical as wastewater-based epidemiology (WBE) progresses. However, large-scale studies on SARS-CoV-2 detection in wastewater from low-and middle-in
Externí odkaz:
https://doaj.org/article/3adea5365c9b47e5bd059515a0f99804
Autor:
Lijin Li, Xiuli Zhang, Xiaoli Wang, Samuel W. Kim, John M. Herndon, Michelle K. Becker-Hapak, Beatriz M. Carreno, Nancy B. Myers, Mark A. Sturmoski, Michael D. McLellan, Christopher A. Miller, Tanner M. Johanns, Benjamin R. Tan, Gavin P. Dunn, Timothy P. Fleming, Ted H. Hansen, S. Peter Goedegebuure, William E. Gillanders
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Background Preclinical studies and early clinical trials have shown that targeting cancer neoantigens is a promising approach towards the development of personalized cancer immunotherapies. DNA vaccines can be rapidly and efficiently manufac
Externí odkaz:
https://doaj.org/article/031af79ff43e4bff85ce49e20a87cccb
Autor:
Fiona J. Ruiz, Matthew Inkman, Ramachandran Rashmi, Naoshad Muhammad, Nishanth Gabriel, Christopher A. Miller, Michael D. McLellan, Michael Goldstein, Stephanie Markovina, Perry W. Grigsby, Jin Zhang, Julie K. Schwarz
Publikováno v:
JCI Insight, Vol 6, Iss 16 (2021)
Persistent HPV infection is causative for the majority of cervical cancer cases; however, current guidelines do not require HPV testing for newly diagnosed cervical cancer. Using an institutional cohort of 88 patients with cervical cancer treated uni
Externí odkaz:
https://doaj.org/article/561372e4f6984d4b841f454f88d97ab7
Autor:
James D. McLellan, Richard E Blanchard
Publikováno v:
AIMS Energy, Vol 6, Iss 2, Pp 339-357 (2018)
Access to reliable electricity eludes many poor rural Afghan communities despite plentiful renewable resources. Micro-generation seems particularly well suited to Afghanistan’s mountainous, decentralised society but even with substantial investment
Externí odkaz:
https://doaj.org/article/99596fd0526e470a80275f281e90bc52
Autor:
Kuan-lin Huang, Shunqiang Li, Philipp Mertins, Song Cao, Harsha P. Gunawardena, Kelly V. Ruggles, D. R. Mani, Karl R. Clauser, Maki Tanioka, Jerry Usary, Shyam M. Kavuri, Ling Xie, Christopher Yoon, Jana W Qiao, John Wrobel, Matthew A. Wyczalkowski, Petra Erdmann-Gilmore, Jacqueline E. Snider, Jeremy Hoog, Purba Singh, Beifang Niu, Zhanfang Guo, Sam Qiancheng Sun, Souzan Sanati, Emily Kawaler, Xuya Wang, Adam Scott, Kai Ye, Michael D. McLellan, Michael C. Wendl, Anna Malovannaya, Jason M. Held, Michael A. Gillette, David Fenyö, Christopher R. Kinsinger, Mehdi Mesri, Henry Rodriguez, Sherri R. Davies, Charles M. Perou, Cynthia Ma, R. Reid Townsend, Xian Chen, Steven A. Carr, Matthew J. Ellis, Li Ding
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Patient-derived xenografts recapitulate major genomic signatures and transcriptome profiles of their original tumours. Here, the authors, performing proteomic and phosphoproteomic analyses of 24 breast cancer PDX models, demonstrate that druggable ca
Externí odkaz:
https://doaj.org/article/1c26a6238dc4471f89a26c07ab836e61
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0232915 (2020)
Chimeric antigen receptor (CAR) T cell therapy is an effective treatment for B cell malignancies, with emerging potential for the treatment of other hematologic cancers and solid tumors. The strength of the promoter within the CAR cassette will alter
Externí odkaz:
https://doaj.org/article/30e3408f75df4963958e005581722360
Autor:
Seyed Mohammad Ali Hosseini Rad, Joshua Colin Halpin, Supannikar Tawinwung, Koramit Suppipat, Nattiya Hirankarn, Alexander D McLellan
Publikováno v:
Immunology & Cell Biology. 100:424-439
Advances made in chimeric antigen receptor (CAR) T cell therapy have revolutionized the treatment and management of certain cancers. Currently, B cell malignancies have been among the few cancers to which CAR T cells have shown persistent and resilie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988284bf14b8ddef83f71583167de372
https://doi.org/10.1111/imcb.12551
https://doi.org/10.1111/imcb.12551
Autor:
William E. Gillanders, S. Peter Goedegebuure, Timothy P. Fleming, Ted Hansen, Elaine R. Mardis, Matthew J. Ellis, Chris A. Miller, Ian S. Hagemann, Mark Sturmoski, Tammi L. Vickery, Nancy Myers, Tina Primeau, Jeremy Hoog, Mike D. McLellan, Lijin Li, Savas D. Soysal, Allegra A. Petti, Shunqiang Li, John M. Herndon, Jasreet Hundal, Samuel Kim, Xiuli Zhang
Next-generation sequencing technologies have provided insights into the biology and mutational landscape of cancer. Here, we evaluate the relevance of cancer neoantigens in human breast cancers. Using patient-derived xenografts from three patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373d4a0c05b6ed776184bd81daf3d8a0
https://doi.org/10.1158/2326-6066.c.6548891
https://doi.org/10.1158/2326-6066.c.6548891
