Zobrazeno 1 - 10
of 535
pro vyhledávání: '"D, McKnight"'
Autor:
Melanie Leguizamon, Colin D. McKnight, Tristan Ponzo, Jason Elenberger, Jarrod J. Eisma, Alexander K. Song, Paula Trujillo, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen, Kilian Hett
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Intravenous arachnoid granulations (AGs) are protrusions of the arachnoid membrane into the venous lumen and function as contributors to the cerebrospinal fluid (CSF) flow circuit. Patients with Parkinson disease (PD) often present with accu
Externí odkaz:
https://doaj.org/article/27b4d6ccc982454ca3f3069043e82b4a
Autor:
Gabriela Pierobon Mays, Kilian Hett, Jarrod Eisma, Colin D. McKnight, Jason Elenberger, Alexander K. Song, Ciaran Considine, Wesley T. Richerson, Caleb Han, Adam Stark, Daniel O. Claassen, Manus J. Donahue
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Background Parkinson’s disease is characterized by dopamine-responsive symptoms as well as aggregation of α-synuclein protofibrils. New diagnostic methods assess α-synuclein aggregation characteristics from cerebrospinal fluid (CSF) and
Externí odkaz:
https://doaj.org/article/c3db04b28b15466ba8491545ab2c8ce4
Autor:
Kilian Hett, Colin D. McKnight, Melanie Leguizamon, Jennifer S. Lindsey, Jarrod J. Eisma, Jason Elenberger, Adam J. Stark, Alexander K. Song, Megan Aumann, Ciaran M. Considine, Daniel O. Claassen, Manus J. Donahue
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Peri-sinus structures such as arachnoid granulations (AG) and the parasagittal dural (PSD) space have gained much recent attention as sites of cerebral spinal fluid (CSF) egress and neuroimmune surveillance. Neurofluid circulation
Externí odkaz:
https://doaj.org/article/530dea9866e74a5692c1c151d83a11d8
Autor:
Jarrod J. Eisma, Colin D. McKnight, Kilian Hett, Jason Elenberger, Caleb J. Han, Alexander K. Song, Ciaran Considine, Daniel O. Claassen, Manus J. Donahue
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background The choroid plexus functions as the blood-cerebrospinal fluid (CSF) barrier, plays an important role in CSF production and circulation, and has gained increased attention in light of the recent elucidation of CSF circulation dysfu
Externí odkaz:
https://doaj.org/article/d19b182c1aa74dad8a522a5900eb7c3c
Autor:
Anna Combes, Lipika Narisetti, Anirban Sengupta, Baxter P. Rogers, Grace Sweeney, Logan Prock, Delaney Houston, Colin D. McKnight, John C. Gore, Seth A. Smith, Kristin P. O’Grady
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Functional MRI (fMRI) of the spinal cord is an expanding area of research with potential to investigate neuronal activity in the central nervous system. We aimed to characterize the functional connectivity features of the human lumbar spinal
Externí odkaz:
https://doaj.org/article/64eca58db0d546f8b8560c5619bfe88c
Autor:
Nathaniel T. Nyema, Aaron D. McKnight, Alexandra G. Vargas-Elvira, Heather M. Schneps, Elizabeth G. Gold, Kevin P. Myers, Amber L. Alhadeff
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101833- (2023)
Objective: The learned associations between sensory cues (e.g., taste, smell) and nutritive value (e.g., calories, post-ingestive signaling) of foods powerfully influences our eating behavior [1], but the neural circuits that mediate these associatio
Externí odkaz:
https://doaj.org/article/94f3f25f403243dfa210edecb76c8b22
Autor:
Margareta A. Clarke, Atlee A. Witt, Ryan K. Robison, Sawyer Fleishman, Anna J.E. Combes, Delaney Houston, Logan E. Prock, Grace Sweeney, Kristin P. O'Grady, Colin D. McKnight, Seth A. Smith
Publikováno v:
NeuroImage, Vol 284, Iss , Pp 120460- (2023)
Background: Susceptibility-weighted imaging (SWI) has been extensively studied in the brain and in diseases of the central nervous system such as multiple sclerosis (MS) providing unique opportunities to visualize cerebral vasculature and disease-rel
Externí odkaz:
https://doaj.org/article/9b02c43dc4ff42d29dbaffddfd108560
Autor:
Kilian Hett, Colin D. McKnight, Jarrod J. Eisma, Jason Elenberger, Jennifer S. Lindsey, Ciaran M. Considine, Daniel O. Claassen, Manus J. Donahue
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Recent studies have suggested alternative cerebrospinal fluid (CSF) clearance pathways for brain parenchymal metabolic waste products. One fundamental but relatively under-explored component of these pathways is the anatomic regio
Externí odkaz:
https://doaj.org/article/97d35ad6575d40ac933231d1887a941b
Autor:
Kurt G. Schilling, Shreyas Fadnavis, Joshua Batson, Mereze Visagie, Anna J.E. Combes, Samantha By, Colin D. McKnight, Francesca Bagnato, Eleftherios Garyfallidis, Bennett A. Landman, Seth A. Smith, Kristin P. O'Grady
Publikováno v:
NeuroImage, Vol 266, Iss , Pp 119826- (2023)
Quantitative diffusion MRI (dMRI) is a promising technique for evaluating the spinal cord in health and disease. However, low signal-to-noise ratio (SNR) can impede interpretation and quantification of these images. The purpose of this study is to ev
Externí odkaz:
https://doaj.org/article/f699cd7d04f54fd482bf0ae092a473cc
Autor:
Anna J.E. Combes, Kristin P. O'Grady, Baxter P. Rogers, Kurt G. Schilling, Richard D. Lawless, Mereze Visagie, Delaney Houston, Logan Prock, Shekinah Malone, Sanjana Satish, Atlee A. Witt, Colin D. McKnight, Francesca Bagnato, John C. Gore, Seth A. Smith
Publikováno v:
NeuroImage: Clinical, Vol 35, Iss , Pp 103127- (2022)
Focal lesions may affect functional connectivity (FC) of the ventral and dorsal networks in the cervical spinal cord of people with relapsing-remitting multiple sclerosis (RRMS). Resting-state FC can be measured using functional MRI (fMRI) at 3T. Thi
Externí odkaz:
https://doaj.org/article/08fcbd9491e241b8a85efe0639081955