Zobrazeno 1 - 10
of 398
pro vyhledávání: '"D, McIlroy"'
Autor:
D. McIlroy, G. Pasinetti, D. Pérez-Pinedo, C. McKean, S. C. Dufour, J. J. Matthews, L. R. Menon, R. Nicholls, R. S. Taylor
Publikováno v:
Life, Vol 14, Iss 9, p 1096 (2024)
The Ediacaran of eastern Newfoundland preserves the world’s oldest known eumetazoan body fossils, as well as the earliest known record of fossilized muscular tissue. Re-examination of the holotype of the eight-armed Haootia quadriformis in terms of
Externí odkaz:
https://doaj.org/article/3560acecefb94c75a7902760c3f12951
Autor:
Ahlima Roumane, George D. Mcilroy, Nadine Sommer, Weiping Han, Lora K. Heisler, Justin J. Rochford
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
AimsIndividuals with lipodystrophies typically suffer from metabolic disease linked to adipose tissue dysfunction including lipoatrophic diabetes. In the most severe forms of lipodystrophy, congenital generalised lipodystrophy, adipose tissue may be
Externí odkaz:
https://doaj.org/article/20b3375b0bc4440c9aaa48799bfe0502
Autor:
Nadine Sommer, Ahlima Roumane, Weiping Han, Mirela Delibegović, Justin J. Rochford, George D. Mcilroy
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 206-216 (2022)
Congenital generalized lipodystrophy type 2 is a serious multisystem disorder with limited treatment options. It is caused by mutations affecting the BSCL2 gene, which encodes the protein seipin. Patients with congenital generalized lipodystrophy typ
Externí odkaz:
https://doaj.org/article/d43c02e6cbf049fbb35281ccc31309ac
Autor:
M. F. Michelle Sim, Elisa Persiani, Md. Mesbah Uddin Talukder, George D. Mcilroy, Ahlima Roumane, J. Michael Edwardson, Justin J. Rochford
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Seipin deficiency causes severe congenital generalized lipodystrophy (CGL) and metabolic disease. However, how seipin regulates adipocyte development and function remains incompletely understood. We previously showed that seipin acts as a sc
Externí odkaz:
https://doaj.org/article/6cddd2655260476b90fb7d607c4f7746
Publikováno v:
Frontiers in Earth Science, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/81d6e1f64e18414e8412bfe97ca9baa9
Autor:
George D. Mcilroy, Karla Suchacki, Anke J. Roelofs, Wulin Yang, Yanyun Fu, Bo Bai, Robert J. Wallace, Cosimo De Bari, William P. Cawthorn, Weiping Han, Mirela Delibegović, Justin J. Rochford
Publikováno v:
Molecular Metabolism, Vol 10, Iss , Pp 55-65 (2018)
Objective: Mutations to the BSCL2 gene disrupt the protein seipin and cause the most severe form of congenital generalised lipodystrophy (CGL). Affected individuals exhibit a near complete loss of white adipose tissue (WAT) and suffer from metabolic
Externí odkaz:
https://doaj.org/article/f1fe08833cf9437a8e9830d0475e85b6
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 1 (2020)
Mutations affecting the BSCL2 gene cause the most severe form of congenital generalised lipodystrophy (CGL). Affected individuals develop severe metabolic complications including diabetes and hepatic steatosis. Bscl2-deficient mice almost entirely re
Externí odkaz:
https://doaj.org/article/8d64762d0fe14cc6ae447f99eaa5483c
Publikováno v:
Estudios Geologicos, Vol 75, Iss 2, Pp e117-e117 (2019)
El holotipo de Beothukis mistakensis en Mistaken Point, Terranova, es el único ejemplar actualmente conocido que puede ser colocado definitivamente dentro de la especie. Las diferencias morfológicas entre el holotipo de B. mistakensis y la especie
Externí odkaz:
https://doaj.org/article/ac97a93ed03b421e88a7593aeea9a7d4
Publikováno v:
Geological Society, London, Special Publications. 522
The ichnology of shallow-marine to transitional environments is a key field of study with respect to understanding the variability of environmental parameters from inshore marginal-marine settings to the offshore transition zone. Over the last decade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acf770f3c56f67c8b7171bf472d0a2b9
https://doi.org/10.1144/sp522
https://doi.org/10.1144/sp522
Autor:
M.N. Sorin, A. Di Maio, L.M. Silva, D. Ebert, C. Delannoy, N.-K. Nguyen, Y. Guerardel, W. Chai, F. Halary, K. Renaudin-Autain, Y. Liu, C. Bressollette-Bodin, T. Stehle, D. McIlroy
BK Polyomavirus (BKPyV) is an opportunistic pathogen that causes nephropathy in kidney transplant recipients. The BKPyV major capsid protein, VP1, engages gangliosides, lipid-linked sialylated glycans at the cell surface, to gain entry into cells. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e2fbfb69e453a06d5b174d0610e133
https://hal.science/hal-03855416/file/2022.07.13.499703v1.full.pdf
https://hal.science/hal-03855416/file/2022.07.13.499703v1.full.pdf
