Secretion of IL-4 from human basophils. The relationship between IL-4 mRNA and protein in resting and stimulated basophils

Autor: D MacGlashan, J M White, S K Huang, S J Ono, J T Schroeder, L M Lichtenstein

Publikováno v: The Journal of Immunology. 152:3006-3016

Purified human basophils have been examined for secretion of IL-4 protein and expression of IL-4 mRNA after stimulation with several secretagogues. In general, these studies used a 15-min preincubation with IL-3, before challenge with secretagogues.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5aa0a455f71fc33e05842ed10eb1b8df
https://doi.org/10.4049/jimmunol.152.6.3006

Expression of CD203c and CD63 in human basophils: relationship to differential regulation of piecemeal and anaphylactic degranulation processes

Autor: D, MacGlashan

Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 40(9)

Activation of human basophils results in the release of many different mediators and the expression of new cell surface proteins. The markers CD63 and CD203c have been used in recent years to assess basophil activation but there have been many studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4ee04cea2f666ebbf0f5b71c2cd6a18
https://pubmed.ncbi.nlm.nih.gov/20633031

IgE-regulated loss, not IgE-regulated synthesis, controls expression of FcepsilonRI in human basophils

Autor: D, MacGlashan, H Z, Xia, L B, Schwartz, J, Gong

Publikováno v: Journal of leukocyte biology. 70(2)

Expression of the high-affinity receptor on basophils and mast cells is modulated by immunoglobulin E (IgE) antibody. Recent studies have shown that modulation occurs through interaction of IgE with the receptor itself, but the mechanisms underlying

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::751bb557c1355c6040c1b5cc74f5ff0e
https://pubmed.ncbi.nlm.nih.gov/11493612

Contributors

Autor: S.N. Abraham, L. Aloe, L. Annunziato, S. Arbilla, E. Arbustini, G.C. Baccari, P.J. Barbosa Pereira, C. Beltrame, J. Bienenstock, S.C. Bischoff, N. V-Blank, U. Blank, S. Bonini, J. Brown, P. Bruhns, C. Calabrese, P. Castaldo, M.K. Church, J.W. Coleman, W. R Coward, M. Daëron, C.A. Dahinden, F. Dal Piaz, J.E. Damen, G. De Crescenzo, A. De Paulis, H. Depoortere, A. De Santis, A.M. Dvorak, M.L. Entman, G. Florio, V. Forte, N.G. Frangogiannis, W.H. Fridman, S.J. Galli, E.W. Gelfand, A. Genovese, M. Gentile, G. Giorgio, J. Goldhill, F. Granata, J.-C. Gutierrez-Ramos, K. Hartmann, C.D. Helgason, B.M. Henz, B. Hermes, K. Hirai, S. Hirota, C.M. Hogaboam, S.T. Holgate, M. Huber, M. Hughes, Humphries R. K, M. Iikura, H.H. Jacobi, O. Johansson, G.L. Johnson, R. Kajekar, Y. Kitamura, P.A. Knight, P.T. Kovanen, S.A. Krilis, G. Krystal, C.S. Lantz, S. Lavens-Phillips, L. Li, H. Liénard, T.-J. Lin, N.W. Lukacs, D. Macglashan Jr, R. Malaviya, O. Malbec, G. Marone, J.S. Marshall, D.D. Metcalfe, A. Micera, H.R.P. Miller, G. Minopoli, S. Minucci, K. Miura, M. Miyamasu, E. Morii, A.C. Myers, T. Nishida, S.H. P. Oliveira, A. Oriente, C. Palumbo, A. Pannaccione, V. Patella, P.H. Pichat, R. Polosa, C. Pothoulakis, P. Pucci, E.J. Quackenbush, S.W. Reddel, P. Romagnani, S. Romagnani, T. Russo, A.M. Sanico, N.M. Schechter, N. Selve, G. Spadaro, R.L. Stevens, S. Strobl, M. Taglialatela, E.M. Thornton, A. Togias, M. Triggiani, M. Tsai, B.J. Undem, P. Valent, L. Verga, A.F. Walls, M. Ware, P. Welker, B.K. Wershil, S.H. Wright, M. Yamaguchi, F.-G. Zhu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0531337140f484139dd1eda47e20e18
https://doi.org/10.1016/b978-012473335-0/50000-3

In vitro regulation of FcepsilonRIalpha expression on human basophils by IgE antibody

Autor: D, MacGlashan, J, McKenzie-White, K, Chichester, B S, Bochner, F M, Davis, J T, Schroeder, L M, Lichtenstein

Publikováno v: Blood. 91(5)

In vivo studies suggested the possibility of an IgE-dependent regulation of high-affinity (FcepsilonRI) IgE receptor expression on basophils. The current studies extend these observations to in vitro cultures of human basophils. Incubation of basophi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9e9fbcebb52a91d7ac1d40ebf1dd5a3
https://pubmed.ncbi.nlm.nih.gov/9473229