Zobrazeno 1 - 10
of 1 778
pro vyhledávání: '"D, Longo"'
Autor:
Sebastian Brandhorst, Morgan E. Levine, Min Wei, Mahshid Shelehchi, Todd E. Morgan, Krishna S. Nayak, Tanya Dorff, Kurt Hong, Eileen M. Crimmins, Pinchas Cohen, Valter D. Longo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract In mice, periodic cycles of a fasting mimicking diet (FMD) protect normal cells while killing damaged cells including cancer and autoimmune cells, reduce inflammation, promote multi-system regeneration, and extend longevity. Here, we perform
Externí odkaz:
https://doaj.org/article/07535cae9755447cbf16d32138fdada8
Autor:
S. Guarrera, D. Vanella, S. Consoli, G. Giudice, S. Toscano, J.M. Ramírez-Cuesta, M. Milani, F. Ferlito, D. Longo
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30543- (2024)
The quantification of soil carbon dioxide (CO2) flux represents an indicator of the agro-ecosystems sustainability. However, the monitoring of these fluxes is quite challenging due to their high spatially-temporally variability and dependence on envi
Externí odkaz:
https://doaj.org/article/0d5575d778034b1c9ba5f7b3bc7867bd
Autor:
Sebastian Brandhorst, Valter D. Longo
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
In recent decades, the study of biological aging has evolved from simplistic theories like the free radical theory to more complex and nuanced perspectives. In particular, the identification of evolutionary conserved genes and signaling pathways that
Externí odkaz:
https://doaj.org/article/494143a2576d48be872de62861075a5a
Autor:
S. Cortellino, V. Quagliariello, G. Delfanti, O. Blaževitš, C. Chiodoni, N. Maurea, A. Di Mauro, F. Tatangelo, F. Pisati, A. Shmahala, S. Lazzeri, V. Spagnolo, E. Visco, C. Tripodo, G. Casorati, P. Dellabona, V. D. Longo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Immune checkpoint inhibitors cause side effects ranging from autoimmune endocrine disorders to severe cardiotoxicity. Periodic Fasting mimicking diet (FMD) cycles are emerging as promising enhancers of a wide range of cancer therapies includ
Externí odkaz:
https://doaj.org/article/84e0c2a914ff43729633608ba3f0023b
Autor:
S. Pappalardo, S. Consoli, G. Longo-Minnolo, D. Vanella, D. Longo, S. Guarrera, A. D’Emilio, J.M. Ramírez-Cuesta
Publikováno v:
Agricultural Water Management, Vol 288, Iss , Pp 108489- (2023)
The main limitation of conventional methods generally used for monitoring the crop water stress lies in the expenditure of time and laboriousness (e.g., stem water potential, Ψstem). In this sense, infrared thermography can assist to identify the cr
Externí odkaz:
https://doaj.org/article/e27f1d64bffa45feb33f239a5093d20c
Autor:
Zoltan Kender, Ekaterina von Rauchhaupt, Daniel Schwarz, Dimitrios Tsilingiris, Lukas Schimpfle, Hannelore Bartl, Valter D. Longo, Martin Bendszus, Stefan Kopf, Stephan Herzig, Sabine Heiland, Julia Szendroedi, Alba Sulaj
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Background and aimCurrent strategies for preventing diabetic sensorimotor polyneuropathy (DSPN) are limited mainly to glucose control but rapid decrease of glycemia can lead to acute onset or worsening of DSPN. The aim of this study was to examine th
Externí odkaz:
https://doaj.org/article/0767b283a2a54e8689fa7efb9a6f8334
Autor:
Alberto Diaz-Ruiz, Tyler Rhinesmith, Laura C. D. Pomatto-Watson, Nathan L. Price, Farzin Eshaghi, Margaux R. Ehrlich, Jacqueline M. Moats, Melissa Carpenter, Annamaria Rudderow, Sebastian Brandhorst, Julie A. Mattison, Miguel A. Aon, Michel Bernier, Valter D. Longo, Rafael de Cabo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Understanding the contribution of diet composition, calories and length of fasting in health maintenance is still challenging. Here the authors compare the effects of cycles of intermittent very low calorie intake achieved with a plant-based fasting
Externí odkaz:
https://doaj.org/article/1dc4b15f57244a44ad6c5f3abdb932b9
Autor:
Laura C. D. Pomatto-Watson, Monica Bodogai, Oye Bosompra, Jonathan Kato, Sarah Wong, Melissa Carpenter, Eleonora Duregon, Dolly Chowdhury, Priya Krishna, Sandy Ng, Emeline Ragonnaud, Roberto Salgado, Paula Gonzalez Ericsson, Alberto Diaz-Ruiz, Michel Bernier, Nathan L. Price, Arya Biragyn, Valter D. Longo, Rafael de Cabo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Caloric restriction (CR) has been shown as an effective intervention to reduce tumorigenesis, but alternative less stringent dietary interventions have also been considered. Here, the authors show that in a murine model of breast cancer CR has a larg
Externí odkaz:
https://doaj.org/article/23bdba50f5d9416ba338e8343d216d8e
Autor:
Stefanie de Groot, Rieneke T. Lugtenberg, Danielle Cohen, Marij J. P. Welters, Ilina Ehsan, Maaike P. G. Vreeswijk, Vincent T. H. B. M. Smit, Hiltje de Graaf, Joan B. Heijns, Johanneke E. A. Portielje, Agnes J. van de Wouw, Alex L. T. Imholz, Lonneke W. Kessels, Suzan Vrijaldenhoven, Arnold Baars, Elma Meershoek-Klein Kranenbarg, Marjolijn Duijm-de Carpentier, Hein Putter, Jacobus J. M. van der Hoeven, Johan W. R. Nortier, Valter D. Longo, Hanno Pijl, Judith R. Kroep, Dutch Breast Cancer Research Group (BOOG)
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Preclinical evidence suggests that a fasting mimicking diet (FMD) can make cancer cells more vulnerable to chemotherapy, while protecting normal cells. In this randomized phase II clinical trial of 131 patients with HER2 negative early stage breast c
Externí odkaz:
https://doaj.org/article/ece7e746301b495eb80ac3a814697099
Autor:
Elske L. van den Burg, Marjolein P. Schoonakker, Petra G. van Peet, M. Elske. van den Akker-van Marle, Ko Willems van Dijk, Valter D. Longo, Hildo J. Lamb, Mattijs E. Numans, Hanno Pijl
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Caloric restriction is an effective way to treat Type 2 diabetes (T2D). However, chronic and severe restriction of food intake is difficult to sustain and is known to promote slower metabolism. Intermittent and frequent fasting ca
Externí odkaz:
https://doaj.org/article/c72b72812cfe4abe817ff623f3de6f5a