IGF2 Peptide-Based LYTACs for Targeted Degradation of Extracellular and Transmembrane Proteins

Autor: Michał Mikitiuk, Jan Barczyński, Przemysław Bielski, Marcelino Arciniega, Urszula Tyrcha, Aleksandra Hec, Andrea D. Lipińska, Michał Rychłowski, Tad A. Holak, Tomasz Sitar

Publikováno v: Molecules, Vol 28, Iss 22, p 7519 (2023)

Lysosome-targeting chimeras (LYTACs) have recently been developed to facilitate the lysosomal degradation of specific extracellular and transmembrane molecular targets. However, the LYTAC particles described to date are based on glycopeptide conjugat

Externí odkaz: https://doaj.org/article/3953071d4d124e7382acdaaa72b81cb4

Long‐time scale simulations of virus‐like particles from three human‐norovirus strains

Autor: Agnieszka G. Lipska, Adam K. Sieradzan, Cezary Czaplewski, Andrea D. Lipińska, Krzysztof M. Ocetkiewicz, Jerzy Proficz, Paweł Czarnul, Henryk Krawczyk, Adam Liwo

Publikováno v: Journal of Computational Chemistry. 44:1470-1483

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66c15ecbeffdcbed6a7c8c8e94a38d33
https://doi.org/10.1002/jcc.27087

Alphaherpesvirus gB Homologs Are Targeted to Extracellular Vesicles, but They Differentially Affect MHC Class II Molecules

Autor: Kinga Grabowska, Magda Wąchalska, Małgorzata Graul, Michał Rychłowski, Krystyna Bieńkowska-Szewczyk, Andrea D. Lipińska

Publikováno v: Viruses, Vol 12, Iss 4, p 429 (2020)

Herpesvirus envelope glycoprotein B (gB) is one of the best-documented extracellular vesicle (EVs)-incorporated viral proteins. Regarding the sequence and structure conservation between gB homologs, we asked whether bovine herpesvirus-1 (BoHV-1) and

Externí odkaz: https://doaj.org/article/01bbf0491d0042288fd214cc8b909839

The Role of IFITM Proteins in Tick-Borne Encephalitis Virus Infection

Autor: Andrea D. Lipińska, Michał Rychłowski, Krystyna Bieńkowska-Szewczyk, Maria Gómez-Herranz, Alicja M Chmielewska, Weronika Hoffmann, Ewelina Krol, Marta Nekulova, Małgorzata Tyrakowska, Ted R. Hupp, Richard D Sloan, Paulina Gach, Kathryn L. Ball, Borivoj Vojtesek

Publikováno v: J Virol
Chmielewska, A M, Gomez Herranz, M, Gach, P, Nekulova, M, Tyrakowska, M, Lipinska, A D, Rychlowski, M, Hoffman, W, Krol, E, Vojtesek, B, Sloan, R D, Bienkowska-Szewczyk, K, Hupp, T R & Ball, K L 2021, ' The role of IFITM proteins in tick-borne encephalitis virus infection ', Journal of Virology . https://doi.org/10.1128/JVI.01130-21

Tick-borne encephalitis virus (TBEV), of the genus Flavivirus, is a causative agent of severe encephalitis in regions of endemicity of northern Asia and central and northern Europe. Interferon-induced transmembrane proteins (IFITMs) are restriction f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d074d249f78759693f7c84e3830a721c
https://europepmc.org/articles/PMC8754218/

Front Cover: Investigation of the Effects of Primary Structure Modifications within the RRE Motif on the Conformation of Synthetic Bovine Herpesvirus 1‐Encoded UL49.5 Protein Fragments (Chem. Biodiversity 2/2021)

Autor: Małgorzata Graul, Agnieszka Kubiś, Emilia Sikorska, Sylwia Rodziewicz-Motowidło, Magdalena J. Ślusarz, Igor Zhukov, Natalia Karska, Andrea D. Lipińska, Franciszek Kasprzykowski

Publikováno v: Chemistry & Biodiversity. 18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::857dd4a80c6e39959db87f2f5323f5c6
https://doi.org/10.1002/cbdv.202100032