Zobrazeno 1 - 10
of 445
pro vyhledávání: '"D, Landes"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
BackgroundSub-thermoneutral housing increases facultative thermogenesis in mice, which may mask the pre-clinical efficacy of anti-obesity strategies that target energy expenditure (EE). Here, we quantified the impact of protonophore treatment on whol
Externí odkaz:
https://doaj.org/article/b3c44cca24474387a1bd3e94379c41da
Autor:
Pedro Barbosa, Reid D. Landes, Stefan Graw, Stephanie D. Byrum, Sirish Bennuri, Leanna Delhey, Chris Randolph, Stewart MacLeod, Andreia Reis, Elisabet Børsheim, Shannon Rose, Eugenia Carvalho
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Epigenetic mechanisms, such as DNA methylation, regulate gene expression and play a role in the development of insulin resistance. This study evaluates how the BMI z-score (BMIz) and the homeostatic model assessment of insulin resistance (HO
Externí odkaz:
https://doaj.org/article/200dc9bbc04240b3977fd1b4e63e7df6
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 9, Iss , Pp 100202- (2023)
Background: In people with Parkinson’s disease (PwPD), Freezing of Gait (FOG) episodes can be levodopa responsive (OFF-FOG) or levodopa unresponsive (ONOFF-FOG). Steady-state gait abnormalities, outside of the freezing episodes themselves also exis
Externí odkaz:
https://doaj.org/article/c215aaf4b24e44cc9727965bf25b6211
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281763 (2023)
BackgroundDeath certificates are crucial for understanding population health trends including the burden of disease mortality. Accurate reporting of causes of death on these records is necessary in order to implement adequate public health policies a
Externí odkaz:
https://doaj.org/article/bb25018d527e4bdc911f512bdeacd863
Autor:
Ashley S. Nemec-Bakk, Vijayalakshmi Sridharan, Parth Desai, Reid D. Landes, Barry Hart, Antiño R. Allen, Marjan Boerma
Publikováno v:
Life, Vol 13, Iss 3, p 795 (2023)
Missions into deep space will expose astronauts to the harsh space environment, and the degenerative tissue effects of space radiation are largely unknown. To assess the risks, in this study, male BALB/c mice were exposed to 500 mGy 5-ion simulated G
Externí odkaz:
https://doaj.org/article/6f173ad8b084444ab9c9a85444c094fc
Publikováno v:
Nursing Reports, Vol 10, Iss 2, Pp 135-145 (2020)
High-quality nursing research is important to healthcare and is precipitated by successful participant recruitment. Young adults aged 18 to 30 years are particularly difficult to recruit due to transitions during this time, which makes it more proble
Externí odkaz:
https://doaj.org/article/fc4856839b8f4eefa82e0cab44840f02
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Background Freezing in the levodopa-medicated-state (ON-state) is a debilitating feature of Parkinson’s disease without treatment options. Studies detailing the distinguishing features between people with freezing of gait that improves with levodop
Externí odkaz:
https://doaj.org/article/eeccede13198415dad27b9b0342f88e9
Publikováno v:
BMC Oral Health, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Inappropriate prescribing of antimicrobials is a significant threat to global public health. In England, approximately 5% of all antimicrobial items are prescribed by dentists, despite the limited indications for their use in the
Externí odkaz:
https://doaj.org/article/d06e57d1c6e04ad4bba2728973047338
Autor:
Ashley S. Nemec-Bakk, Vijayalakshmi Sridharan, John W. Seawright, Gregory A. Nelson, Maohua Cao, Preeti Singh, Amrita K. Cheema, Bhaldev Singh, Yaoxiang Li, Igor Koturbash, Isabelle R. Miousse, Laura E. Ewing, Charles M. Skinner, Reid D. Landes, John D. Lowery, Xiao-Wen Mao, Sharda P. Singh, Marjan Boerma
Publikováno v:
Life Sciences in Space Research. 37:78-87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2814ec1335bcac0c99aec3074cb988df
https://doi.org/10.1016/j.lssr.2023.03.008
https://doi.org/10.1016/j.lssr.2023.03.008
RRx-001 Radioprotection: Enhancement of Survival and Hematopoietic Recovery in Gamma-Irradiated Mice
Autor:
Kimberly J. Jurgensen, William K. J. Skinner, Bryan Oronsky, Nacer D. Abrouk, Andrew E. Graff, Reid D. Landes, William E. Culp, Thomas A. Summers, Lynnette H. Cary
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The present studies evaluate the in vivo prophylactic radioprotective effects of 1-bromoacetyl-3, 3-dinitroazetidine (RRx-001), a phase III anticancer agent that inhibits c-myc and downregulates CD-47, after total body irradiation (TBI), in lethally
Externí odkaz:
https://doaj.org/article/07bf6d1f47074698979c2b0221d0f085