Zobrazeno 1 - 10
of 145
pro vyhledávání: '"D, Konopińska"'
Publikováno v:
International journal of tissue reactions. 25(2)
The distribution in parts of the brain and internal organs of 125J-labeled leucopyrokinin (LPK), an insect myotropic peptide injected into the lateral brain ventricle was determined in rats. A high accumulation of this peptide in adrenals and in the
Publikováno v:
Polish journal of pharmacology. 53(1)
To explain the role of the Thr5 residue of proctolin (Arg-Tyr-Leu-Pro-Thr) in the myotropic activity of this insect neuropeptide, we synthesized two groups of its analogues: 1) Arg-Tyr-Leu-Pro-X-OH with X = Val (1), D-Val (2), Ile (3), D-Ile (4), Ala
Autor:
W, Szeszel-Fedorowicz, G, Rosiński, J, Issberner, R, Osborne, I, Janssen, A, De Loof, D, Konopińska
Publikováno v:
Acta poloniae pharmaceutica.
Novel analogs, modified by L- or D- phenylglycine and p-substituted derivatives, of the neuromodulator proctolin (Arg-Tyr-Leu-Pro-Thr) and of the Trypsin Modulating Oostatic Factor from the gray flesh fly Neobellieria bullata (Neb-TMOF-Asn-Pro-Thr-As
Publikováno v:
Polish journal of pharmacology. 51(1)
We have extended our studies on the structure-activity relationship in neuropeptide proctolin (Arg-Tyr-Leu-Pro-Thr) by evaluating the effects of a series of proctolin analogues modified in position 2 of the peptide chain, including: [Phe(p-Cl)2]- (1)
Publikováno v:
Polish journal of pharmacology. 50(2)
We have extended our work on structure/activity relationship of neuropeptide proctolin (H-Arg-Tyr-Leu-Pro-Thr-OH) by evaluating the effects of the following proctolin analogues: H-X1-Tyr-Leu-Pro-Thr-OH, where X1 = D-Arg (1), N-Me-Arg (2), Can (3), D-
Autor:
D, Konopińska
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 49(6)
In the present paper, the literature describing synthetic, biological and conformational studies on the insect neuropeptide proctolin (H-Arg-Tyr-Leu-Pro-Thr-OH) and its analogues is summarized. The paper covers proctolin and its 80 analogues modified
Autor:
A, Plech, M, Rykaczewska-Czerwińska, H, Bartosz-Bechowski, D, Lombarska-Sliwińska, M, Małota, M, Szewczyk, R, Brus, D, Konopińska
Publikováno v:
Polish journal of pharmacology. 49(2-3)
The insect myotropic octapeptide leucopyrokinin Glp-Thr-Ser-Phe-Thr-Pro-Arg-Leu-amide (LPK or Lem-PK) (1) and its truncated analogues without the first N-terminal amino acids [2-8]-LPK (2) as well as devoid of the first, second and third N-terminal a
Publikováno v:
Polish journal of pharmacology. 49(1)
The central action of periplanetin CC-1 (Pea-HrTH) (Glp-Val-Asn-Phe-Ser-Pro-Asn-TrpNH2), octapeptide of the insect adipokinetic hormone family (AKH-family), isolated from American cockroach-Periplaneta americana, was studied in Albino Swiss mice (20-
Publikováno v:
Polish journal of pharmacology and pharmacy. 44(5)
Six proctolin analogs modified in position 3 of peptide chain such as Arg-Tyr-X-Pro-Thr where X = Gly (1), Val (2), Pro (3), Thr (4), Acp (1-aminocyclopentane-1-carboxylic acid residue) (5), and Ach (1-aminocyclohexane-1-carboxylic acid residue) (6)
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 27(1-2)
Five tuftsin analogues, containing one or two of the basic amino acid residues, respectively in position: 2, 3, 2 and 4, 2 and 3--of the peptide chain, were synthesized and tested for biologic activity by the Najjar test.