Zobrazeno 1 - 10
of 2 667
pro vyhledávání: '"D, Howe"'
Autor:
Matthew D. Howe, Karysa J. Britton, Hannah E. Joyce, William Menard, Sheina Emrani, Zachary J. Kunicki, Melanie A. Faust, Brittany C. Dawson, Meghan C. Riddle, Edward D. Huey, Shorena Janelidze, Oskar Hansson, Stephen P. Salloway
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background With the approval of disease-modifying treatments (DMTs) for early Alzheimer’s disease (AD), there is an increased need for efficient and non-invasive detection methods for cerebral amyloid-β (Aβ) pathology. Current methods, i
Externí odkaz:
https://doaj.org/article/45714cef87b14c3381fb405472bc50ab
Autor:
Ermias Gebrekrstos Tesfamariam, Dennis Ssekimpi, Sarajeen Saima Hoque, Huan Chen, Joshua D. Howe, Chao Zhou, Yue-xiao Shen, Youneng Tang
Publikováno v:
Water Science and Technology, Vol 89, Iss 9, Pp 2440-2456 (2024)
1,4-Dioxane concentration in most contaminated water is much less than 1 mg/L, which cannot sustain the growth of most reported 1,4-dioxane-metabolizing pure cultures. These pure cultures were isolated following enrichment of mixed cultures at high c
Externí odkaz:
https://doaj.org/article/d915c30f36b840d29502283b895e99c5
Autor:
Amanda M. Hughes, Stuart W. Flint, Ken Clare, Antonis A. Kousoulis, Emily R. Rothwell, Helen Bould, Laura D. Howe
Publikováno v:
The Lancet Regional Health. Europe, Vol 40, Iss , Pp 100895- (2024)
Summary: Background: Obesity is highly stigmatized, with negative obesity-related stereotypes widespread across society. Internalized weight stigma (IWS) is linked to negative outcomes including poor mental health and disordered eating. Previous evid
Externí odkaz:
https://doaj.org/article/08efd3a8ef4d47d39d7a074a6cabdbf8
Autor:
Yangci Liu, Haoming Zhai, Helen Alemayehu, Jérôme Boulanger, Lee J. Hopkins, Alicia C. Borgeaud, Christina Heroven, Jonathan D. Howe, Kendra E. Leigh, Clare E. Bryant, Yorgo Modis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract NLRP3 induces caspase-1-dependent pyroptotic cell death to drive inflammation. Aberrant activity of NLRP3 occurs in many human diseases. NLRP3 activation induces ASC polymerization into a single, micron-scale perinuclear punctum. Higher reso
Externí odkaz:
https://doaj.org/article/0dd2c4667aa94b67b8bb0ece60d3f339
Autor:
Alice R Carter, Gemma L Clayton, M Carolina Borges, Laura D Howe, Rachael A Hughes, George Davey Smith, Deborah A Lawlor, Kate Tilling, Gareth J Griffith
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background There are many ways in which selection bias might impact COVID-19 research. Here we focus on selection for receiving a polymerase-chain-reaction (PCR) SARS-CoV-2 test and how known changes to selection pressures over time may bias
Externí odkaz:
https://doaj.org/article/bebc88621a264ddb8f00bf0f3c4057aa
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Few studies have investigated associations between adiposity and reproductive factors using causal methods, both of which have a number of consequences on women’s health. Here we assess whether adiposity at different points in t
Externí odkaz:
https://doaj.org/article/cf44f428fa4c45da8f007931b0805836
Autor:
Teri-Louise North, Sean Harrison, Deborah C Bishop, Robyn E Wootton, Alice R Carter, Tom G Richardson, Rupert A Payne, Chris Salisbury, Laura D Howe
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Multimorbidity, typically defined as having two or more long-term health conditions, is associated with reduced wellbeing and life expectancy. Understanding the determinants of multimorbidity, including whether they are causal, ma
Externí odkaz:
https://doaj.org/article/995b2b9d434d4c2399d8ef82085605cd
Autor:
Bryan K. Ward, Kirsten A. Loffell, John P. Walsh, Warwick D. Howe, Suzanne J. Brown, Scott G. Wilson
Publikováno v:
Case Reports in Endocrinology, Vol 2024 (2024)
Background. Primary hyperparathyroidism (PHPT) and familial hypocalciuric hypercalcaemia (FHH) are common causes of hypercalcaemia. Patients are mostly asymptomatic in the case of FHH and often so in the case of PHPT. In addition, biochemical paramet
Externí odkaz:
https://doaj.org/article/38cf5fa188e34a9792bfe29bfe3c2d19
Autor:
Elizabeth Winn, Madeleine Kissane, Samuel WD Merriel, Thomas Brain, Victoria A Silverwood, Ishbel Orla Whitehead, Laura D Howe, Rupert A Payne, Polly Duncan, on behalf of the Primary Care Academic Collaborative (PACT)
Publikováno v:
BJGP Open, Vol 7, Iss 4 (2023)
Background: Older housebound people are an under-researched group for whom achieving good primary health care can be resource intensive. Aims: To describe the characteristics and healthcare use of older (≥65 years) housebound people; explore clinic
Externí odkaz:
https://doaj.org/article/5f7d305794c6442e84b25cd3c57ccca0
Autor:
Kate N. O'Neill, Joshua A. Bell, George Davey Smith, Abigail Fraser, Laura D. Howe, Patricia M. Kearney, Oliver Robinson, Kate Tilling, Peter Willeit, Linda M. O'Keeffe
Publikováno v:
EBioMedicine, Vol 98, Iss , Pp 104884- (2023)
Summary: Background: Socioeconomic inequalities in cardiovascular disease risk begin early in life and are more pronounced in females than males later in life. Causal atherogenic traits explaining this are not well understood. We explored sex-specifi
Externí odkaz:
https://doaj.org/article/1dd9abd53ba342e580da35b0fecac055