Zobrazeno 1 - 10 of 81 pro vyhledávání: '"D, Holderbaum"'
1
A newly described hereditary cartilage debonding syndrome
Autor: Maripat Corr, Dennis A. Carson, Cathleen J. Ciesielski, T. Malvitz, Roland W. Moskowitz, D. Holderbaum
Publikováno v: Arthritis & Rheumatism. 52:3300-3304
Objective We describe a hereditary chondropathy characterized by extreme cartilage friability and cartilage–bone debonding, which has not previously been described in the literature. We also describe initial studies into the molecular basis of this
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191057b2f8beff69572dcb8c40dbc5f0
https://doi.org/10.1002/art.21352
Zobrazit plný text záznamu
2
Osteoarthritis in Children Associated with a Mutation in the Type II Procollagen Gene (COL2A1)
Autor: Richard J. Mier, Rebecca Ferguson, Roland W. Moskowitz, D. Holderbaum
Publikováno v: Molecular Genetics and Metabolism. 74:338-341
A single-base mutation resulting in an arginine-519–cysteine (R519C) mutation of type II procollagen (COL2A1) has been shown to result in precocious osteoarthritis with mild spinal chondrodysplasia without severe foreshortening (OMIM 604864). The n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3334679f9214e538ca60ba21317387e
https://doi.org/10.1006/mgme.2001.3250
Zobrazit plný text záznamu
3
Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia
Autor: S. Bahabri, Andrea Superti-Furga, Jamil Al-Alami, J K Herd, W. Van Hul, Jean Roudier, H Rezai-Delui, M. Le Merrer, Wafaa M. Suwairi, J R Hurvitz, D Holderbaum, Hatem El-Shanti, Richard M. Pauli, Eric Legius, E Van Hul, Matthew L. Warman
Publikováno v: Nature genetics
Members of the CCN (for CTGF, cyr61/cef10, nov) gene family encode cysteine-rich secreted proteins with roles in cell growth and differentiation1. Cell-specific and tissue-specific differences in the expression and function of different CCN family me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e342bc514bf910e0789dfac790954430
https://doi.org/10.1038/12699
Zobrazit plný text záznamu
5
Changes in serum cartilage marker levels indicate altered cartilage metabolism in families with the osteoarthritis-related type II collagen gene COL2A1 mutation
Autor: Tore Saxne, A R Poole, D. Holderbaum, Mirela Ionescu, Roland W. Moskowitz, P Jones, Dick Heinegård, J. F. Bleasel
Publikováno v: Arthritis & Rheumatism. 42:39-45
Objective The Arg519–Cys mutation in type II collagen results in severe, precocious familial osteoarthritis (OA) in 100% of carriers within the first 3 decades of life. The carrier population provided a well-defined patient population for the study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d9ada1f21a8aa1850939e79b1d6f680
https://doi.org/10.1002/1529-0131(199901)42:1<39::aid-anr5>3.0.co
Zobrazit plný text záznamu
6
Phenotypic modulation of newly synthesized proteoglycans in human cartilage and chondrocytes
Autor: Victor M. Goldberg, Charles J. Malemud, Tariq M. Haqqi, D. Holderbaum, Thomas M. Hering, Robert S. Papay
Publikováno v: Osteoarthritis and Cartilage. 3:227-238
The proteoglycans synthesized by human osteoarthritic femoral head cartilage and nonarthritic articular cartilage age-matched to the osteoarthritic cartilage specimens was studied in explant cultures and in chondrocytes generated by explant outgrowth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50e4ec73e2e7eb35c5e36f2de7ecbc7
https://doi.org/10.1016/s1063-4584(05)80014-7
Zobrazit plný text záznamu
7
BUB/BnJ (H-2q) is a TCR deletion mutant mouse strain (TCR V beta a, KJ16-) that is susceptible to type II collagen-induced arthritis
Autor: R A Ortman, D Holderbaum, X M Qu, S Banerjee, T M Haqqi
Publikováno v: The Journal of Immunology. 152:4175-4182
Type II collagen-induced arthritis (CIA) in mice is an animal model of autoimmune inflammatory arthritis. Arthritis is induced in susceptible strains of mice (H-2q and H-2r) after immunization with heterologous or autologous type II collagen in CFA.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b250c3abd5efee46d777640b4deb0e8f
https://doi.org/10.4049/jimmunol.152.8.4175
Zobrazit plný text záznamu
8
Human Cartilage from Late Stage Familial Osteoarthritis Transcribes Type II Collagen mRNA Encoding a Cysteine in Position 519
Autor: Tariq M. Haqqi, Charles J. Malemud, D. Holderbaum, Roland W. Moskowitz
Publikováno v: Biochemical and Biophysical Research Communications. 192:1169-1174
A single base change resulting in the substitution of Cys for Arg at position 519 of the type II collagen triple helix is a predisposing factor in the pathogenesis of a precocious-onset form of familial osteoarthritis associated with a mild chondrody
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db39a033bac7f3566ebcd7f073108e96
https://doi.org/10.1006/bbrc.1993.1539
Zobrazit plný text záznamu
10
Changes in serum cartilage marker levels indicate altered cartilage metabolism in families with the osteoarthritis-related type II collagen gene COL2A1 mutation
Autor: J F, Bleasel, A R, Poole, D, Heinegård, T, Saxne, D, Holderbaum, M, Ionescu, P, Jones, R W, Moskowitz
Publikováno v: Arthritis and rheumatism. 42(1)
The Arg5l9-Cys mutation in type II collagen results in severe, precocious familial osteoarthritis (OA) in 100% of carriers within the first 3 decades of life. The carrier population provided a well-defined patient population for the study of serum ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::50328164001520bb5384783f42823441
https://pubmed.ncbi.nlm.nih.gov/9920012
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje