Zobrazeno 1 - 10
of 302
pro vyhledávání: '"D, Hock"'
Autor:
Barry D Hock, Liping Goddard, Sean A MacPherson, Matthew Strother, David Gibbs, John F Pearson, Judith L McKenzie
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0290793 (2023)
The efficacy of PD-1 monoclonals such as pembrolizumab can be modulated by the signals delivered via their Fc region. Tumour/inflammation associated proteases can generate F(ab')2 fragments of therapeutic monoclonals, and subsequent recognition of F(
Externí odkaz:
https://doaj.org/article/5c5343f1c5614282a9d7c4d55c3316c4
Publikováno v:
Free Radical Research. 56:366-377
CD36 is the key scavenger receptor driving the formation of cholesterol-loaded foam cells, the principal cellular component of atherosclerotic plaques. CD36 is down regulated by 7,8-dihydroneopterin, a potent superoxide and hypochlorite scavenging an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd1d6dde3d51072c71a0011a27d9c0b
https://doi.org/10.1080/10715762.2022.2114904
https://doi.org/10.1080/10715762.2022.2114904
Publikováno v:
European Journal of Radiology Open, Vol 2, Iss C, Pp 32-38 (2015)
Purpose: We evaluated the rate of significant colonic and extra-colonic abnormalities at computed tomography colonography (CTC), according to symptoms and age. Materials and methods: We retrospectively evaluated 7361 consecutive average-risk subjects
Externí odkaz:
https://doaj.org/article/73e91e37ec574f1794bdfef0d1384461
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172858 (2017)
Chronic lymphocytic leukemia (CLL) is associated with T cell dysfunction. Activated CLL cells are found within the lymphoid tumor micro-environment and overcoming immuno-suppression induced by these cells may improve anti-CLL immune responses. Howeve
Externí odkaz:
https://doaj.org/article/648b66cda15e476387039ffffba17694
Autor:
Linda A. Buss, Abel Damien Ang, Bridget A. Robinson, Barry D. Hock, Gabi U. Dachs, Margaret J. Currie, Liping Goddard
Publikováno v:
Immunology Letters. 234:13-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346ecb7a39493eec9b0ed9693b3baf84
https://doi.org/10.1016/j.imlet.2021.04.003
https://doi.org/10.1016/j.imlet.2021.04.003
Autor:
Barry D. Hock, Linda A. Buss, Abel Damien Ang, Bridget A. Robinson, Margaret J. Currie, Troy L. Merry, Gabi U. Dachs
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258831 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258831 (2021)
Cancer causes mitochondrial alterations in skeletal muscle, which may progress to muscle wasting and, ultimately, to cancer cachexia. Understanding how exercise adaptations are altered by cancer and cancer treatment is important for the effective des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388ec87181dfd1a33b4951ae4531d56f
http://europepmc.org/articles/PMC8525738
http://europepmc.org/articles/PMC8525738
Autor:
John F. Pearson, Peter Ganly, Katie S. Mulholland, Judith L. McKenzie, Sean A. MacPherson, Barry D. Hock
Publikováno v:
Internal Medicine Journal. 49:598-606
BACKGROUND The impact of changes in novel agent (NA) usage on the survival of multiple myeloma (MM) patients in real-world hospital settings is unclear. In New Zealand (NZ) in 2011, frontline bortezomib became available and thalidomide availability w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fe87728d21cc13a0070b6c856e1bac
https://doi.org/10.1111/imj.14155
https://doi.org/10.1111/imj.14155
Autor:
Barry D. Hock, Shwan Karim, Michael Schultz, Lisa K. Stamp, Esther T. Johanna Helms, Paula E. Keating, Murray L. Barclay
Publikováno v:
Internal Medicine Journal. 49:513-518
BACKGROUND Therapeutic drug monitoring of anti-tumour necrosis factor (TNF) drugs and anti-drug antibodies (ADA) is now recommended in the treatment of inflammatory bowel disease. However, assay types and drug concentration thresholds are still debat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8036b97dbfba9ae39c51f104d54e3a
https://doi.org/10.1111/imj.14064
https://doi.org/10.1111/imj.14064
Autor:
Stewart M. Smith, Barry D. Hock, Christopher J McEntyre, Judith L. McKenzie, Paula E. Keating, Liping Goddard
Publikováno v:
Therapeutic Drug Monitoring. 40:705-715
The measurement of anti-drug antibody (ADA) levels in adalimumab (ADAL)-treated and infliximab (IFX)-treated patients is critical for guiding therapeutic strategies. The homogeneous mobility shift assay (HMSA) and affinity capture elution (ACE) assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886522304f71e0af78d073c8466688ef
https://doi.org/10.1097/ftd.0000000000000553
https://doi.org/10.1097/ftd.0000000000000553
Autor:
Linda A. Buss, Gabi U. Dachs, Bridget A. Robinson, Abel Damien Ang, Margaret J. Currie, Barry D. Hock, Thomas Williams
Publikováno v:
Immunology letters. 239
Immune checkpoint inhibition is highly effective in treating a subset of patients with certain cancers, such as malignant melanoma. However, a large proportion of patients will experience treatment resistance, and other tumour types, such as breast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde831838728355c390f0b09339a8621
https://pubmed.ncbi.nlm.nih.gov/34480981
https://pubmed.ncbi.nlm.nih.gov/34480981