Zobrazeno 1 - 10
of 451
pro vyhledávání: '"D, Healey"'
Autor:
David W. James, Marcos Quintela, Lisa Lucini, Nour Al Abdullah Al Kafri, Gareth D. Healey, Nicholas Jones, Kinza Younas, Adnan Bunkheila, Lavinia Margarit, Lewis W. Francis, Deyarina Gonzalez, R. Steven Conlan
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/5f194a976b634867ac7c256c464e0201
Autor:
David W. James, Marcos Quintela, Lisa Lucini, Nour Al Abdullah Al Kafri, Gareth D. Healey, Nicholas Jones, Kinza Younas, Adnan Bunkheila, Lavinia Margarit, Lewis W. Francis, Deyarina Gonzalez, R. Steven Conlan
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Decidualisation, the process whereby endometrial stromal cells undergo morphological and functional transformation in preparation for trophoblast invasion, is often disrupted in women with polycystic ovary syndrome (PCOS) resulting in complications w
Externí odkaz:
https://doaj.org/article/632dc9cfe14a49ed89a15573acdfcfd0
Autor:
Robert D. Healey, Louise Couillaud, François Hoh, Assia Mouhand, Aurelien Fouillen, Pierre Couvineau, Sébastien Granier, Cédric Leyrat
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract The polyhistidine (6XHis) motif is one of the most ubiquitous protein purification tags. The 6XHis motif enables the binding of tagged proteins to various metals, which can be advantageously used for purification with immobilized metal affin
Externí odkaz:
https://doaj.org/article/f602ea4bca4545ce95b78eca1097b926
Autor:
Paul D. Healey
In recent years the number of Americans who have decided to handle their own legal affairs without the help of a lawyer has skyrocketed. Ranging from people writing their own wills or drafting a contract to those trying to represent themselves in cou
Autor:
Simone Pisano, Stefania Lenna, Gareth D. Healey, Fereshteh Izardi, Lucille Meeks, Yajaira S. Jimenez, Oscar S Velazquez, Deyarina Gonzalez, Robert Steven Conlan, Bruna Corradetti
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 10, Pp n/a-n/a (2021)
Abstract Background Ovarian cancer (OC) is typically diagnosed late, associated with high rates of metastasis and the onset of ascites during late stage disease. Understanding the tumor microenvironment and how it impacts the efficacy of current trea
Externí odkaz:
https://doaj.org/article/f9cb144defa142c1bd56460ce73823b3
Autor:
Zainab Khan, Gareth D. Healey, Roberta Paravati, Nidhika Berry, Eugene Rees, Lavinia Margarit, Deyarina Gonzalez, Simon Emery, Robert Steven Conlan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
ObjectivesTo investigate whether women with overactive bladder (OAB) symptoms and no evidence of clinical infection by conventional clean-catch midstream urine cultures have alternative indicators of sub-clinical infection.Patients/Subjects, Material
Externí odkaz:
https://doaj.org/article/4f9905cdad8b40468eb98b27d5792a6a
Autor:
David W. James, Marcos Quintela, Lisa Lucini, Noor K. Alkafri, Gareth D. Healey, Kinza Younas, Adnan Bunkheila, Lavinia Margarit, Lewis W. Francis, Deyarina Gonzalez, 1 and R. Steven Conlan
Publikováno v:
Frontiers in Endocrinology; 2024, p1-13, 13p
Autor:
Gareth D. Healey, Belen Pan-Castillo, Jezabel Garcia-Parra, Julia Davies, Shaun Roberts, Eilir Jones, Kalyan Dhar, Sarika Nandanan, Nasima Tofazzal, Luke Piggott, Richard Clarkson, Gillian Seaton, Asa Frostell, Tim Fagge, Colin McKee, Lavinia Margarit, R. Steven Conlan, Deyarina Gonzalez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background The treatment of endometrial cancer (EC), the most common gynecological cancer, is currently hampered by the toxicity of current cytotoxic agents, meaning novel therapeutic approaches are urgently required. Methods A cohort of 161
Externí odkaz:
https://doaj.org/article/8a6b676f57f741f9b1895a074cb50d87
Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy
Autor:
Ieva Vasiliauskaité-Brooks, Robert D. Healey, Pascal Rochaix, Julie Saint-Paul, Rémy Sounier, Claire Grison, Thierry Waltrich-Augusto, Mathieu Fortier, François Hoh, Essa M. Saied, Christoph Arenz, Shibom Basu, Cédric Leyrat, Sébastien Granier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Alkaline ceramidases (ACERs) are a class of poorly understood transmembrane enzymes controlling the homeostasis of ceramides. Here authors solve the Xray structure of human ACER3 and uncover a Ca2+ binding site providing an explanation for the known
Externí odkaz:
https://doaj.org/article/9944c8e0584f421dad2c7d0bf7a0b051
Autor:
Bat‐Erdene Jugder, Susanne Bohl, Helene Lebhar, Robert D. Healey, Mike Manefield, Christopher P. Marquis, Matthew Lee
Publikováno v:
Microbial Biotechnology, Vol 10, Iss 6, Pp 1640-1648 (2017)
Summary We report herein the purification of a chloroform (CF)‐reducing enzyme, TmrA, from the membrane fraction of a strict anaerobe Dehalobacter sp. strain UNSWDHB to apparent homogeneity with an approximate 23‐fold increase in relative purity
Externí odkaz:
https://doaj.org/article/9f2af767aec64d8cad186cac1e01f525