Zobrazeno 1 - 10
of 1 766
pro vyhledávání: '"D, Hammock"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Oxylipins are a group of bioactive fatty acid metabolites generated via enzymatic oxygenation. They are notably involved in inflammation, pain, vascular tone, hemostasis, thrombosis, immunity, and coagulation. Oxylipins have become the focus
Externí odkaz:
https://doaj.org/article/c5206c6a1782433c8a8dc0ac63a80288
Autor:
William K. Schmidt, Irene Cortés‐Puch, Cindy B. McReynolds, Glenn E. Croston, Sung Hee Hwang, Jun Yang, Theresa L. Pedersen, Karen M. Wagner, Theresa T. Pham, Thomas Hunt, Bruce D. Hammock
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 9, Pp n/a-n/a (2024)
Abstract Chronic pain represents a significant unmet medical need, affecting one‐fifth of the U.S. population. EC5026 is a small molecule inhibitor of the enzyme soluble epoxide hydrolase (sEH) which is being developed as a novel non‐opioid, non
Externí odkaz:
https://doaj.org/article/d23ba464802241f69df3a0fdd283dc0d
Autor:
Tayleur D. White, Abdulaziz Almutairi, Ying Gai-Tusing, Daniel J. Stephenson, Benjamin D. Stephenson, Charles E. Chalfant, Xiaoyong Lei, Brian Lu, Bruce D. Hammock, Teresa P. DiLorenzo, Sasanka Ramanadham
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWe reported that Ca2+-independent phospholipase A2β (iPLA2β)–derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. As CD4+ and CD8+ T cells are critical in promoting β-cell death, we tested the hypothesis that iDL signalin
Externí odkaz:
https://doaj.org/article/588f970bbb8d45fbb26e60d608d19390
Autor:
Yun Gui, Yun Zhao, Pengyan Liu, Yulong Wang, Xinxin Mao, Chifang Peng, Bruce D. Hammock, Cunzheng Zhang
Publikováno v:
ACS Omega, Vol 9, Iss 6, Pp 7075-7084 (2024)
Externí odkaz:
https://doaj.org/article/03e2ca24e17d4e44920a773ac8551e53
Autor:
Jeannes Angelia, Leah Duong, Faye Yun, Anesa Mesic, Cassandra Yuan, Daniel Carr, Siena Gunari, Paula K. Hudson, Christophe Morisseau, Bruce D. Hammock, Ram Kandasamy, Stevan Pecic
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32262- (2024)
Simultaneous inhibition of soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) with a single small molecule represents a novel therapeutic approach in treating inflammatory pain, since both targets are involved in pain and inflammat
Externí odkaz:
https://doaj.org/article/a9debe63a822457898455455adf78d0e
Nanobody-based bispecific T-cell engager (Nb-BiTE): a new platform for enhanced T-cell immunotherapy
Autor:
Xiao-mei Yang, Xuan-dong Lin, Wei Shi, Shen-xia Xie, Xia-ning Huang, Shi-hua Yin, Xiao-bing Jiang, Bruce D. Hammock, Zhi Ping Xu, Xiao-ling Lu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/d59055c881184cd391204872905dfa75
Publikováno v:
Biosensors, Vol 14, Iss 7, p 322 (2024)
Patulin, an emerging mycotoxin with high toxicity, poses great risks to public health. Considering the poor antibody production in patulin immunization, this study focuses on the four-dimensional data-independent acquisition (4D-DIA) quantitative pro
Externí odkaz:
https://doaj.org/article/de0f1263635b449ea24d7669c35c88d9
Autor:
Manatsaphon Sukmak, Thin Su Kyaw, Kanokwan Nahok, Amod Sharma, Atit Silsirivanit, Worachart Lert-Itthiporn, Deanpen Japrung, Somchai Pinlaor, Sirirat Anutrakulchai, Carlo Selmi, Carolyn M Slupsky, Bruce D Hammock, Ubon Cha'on
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0309728 (2024)
Monosodium glutamate (MSG) is a widely used food additive with conflicting evidence regarding its potential effects on human health, with proposed relevance for obesity and metabolic syndrome (MetS) or chronic kidney disease. As being able to accurat
Externí odkaz:
https://doaj.org/article/4577e3eab54741db8c82ee33bf6abd1e
Autor:
Daniel Carr, Christopher Chin, Tiffany Chacon, Monijeh Khoja Herawi, Michael Gonzalez, Ryan West, Christophe Morisseau, Bruce D. Hammock, Stevan Pecic, Ram Kandasamy
Publikováno v:
BBA Advances, Vol 6, Iss , Pp 100119- (2024)
Pain arising from trigeminal systems such as headache is common, debilitating, and current treatments (e.g., sumatriptan) are limited. New treatments that target novel mechanisms of action may be required to innovate both short- and long-term pain th
Externí odkaz:
https://doaj.org/article/40c250400278494e80f2caeb253914f4
Autor:
Chuanzhen Zhang, Wei Li, Xiyuan Li, Debin Wan, Savannah Mack, Jingjing Zhang, Karen Wagner, Chang Wang, Bowen Tan, Jason Chen, Ching-Wen Wu, Kaori Tsuji, Minoru Takeuchi, Ziping Chen, Bruce D Hammock, Kent E Pinkerton, Jun Yang
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307533 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0266608.].
Externí odkaz:
https://doaj.org/article/1b5ad8c40c874b79b84d2c5ee48ba19e