Výsledky vyhledávání

HRG4 (UNC119) mutation found in cone-rod dystrophy causes retinal degeneration in a transgenic model

Autor: A, Kobayashi, T, Higashide, D, Hamasaki, S, Kubota, H, Sakuma, W, An, T, Fujimaki, M J, McLaren, R G, Weleber, G, Inana

Publikováno v: Investigative ophthalmologyvisual science. 41(11)

To investigate the function and pathogenicity of HRG4, a photoreceptor synaptic protein homologous to the Caenorhabditis elegans neuroprotein UNC119.HRG4 was screened for mutations in patients with various retinopathies, and a transgenic mouse model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::285d3aad27ae5210ee1243eb4eeaa8c4
https://pubmed.ncbi.nlm.nih.gov/11006213

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Ultrastructural and ERG findings in mice with adenomatous polyposis coli gene disruption

Autor: D M, Marcus, A K, Rustgi, D, Defoe, R, Kucherlapati, W, Edelmann, D, Hamasaki, G I, Liou, S B, Smith

Publikováno v: Molecular vision. 6

In order to continue the previous morphological studies of eyes from mice with adenomatous polyposis coli (APC) gene mutation at codon 1638, we determined the ultrastructural and electrophysiologic characteristics of these eyes.Thirty-eight eyes from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f08ae1a3a234aaadf134470cca71288a
https://pubmed.ncbi.nlm.nih.gov/10982921

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Local carboplatin therapy in transgenic murine retinoblastoma

Autor: J W, Harbour, T G, Murray, D, Hamasaki, N, Cicciarelli, E, Hernández, B, Smith, J, Windle, J M, O'Brien

Publikováno v: Investigative ophthalmologyvisual science. 37(9)

To determine the efficacy and toxicity associated with intraocular delivery of carboplatin in the treatment of murine transgenic hereditary retinoblastoma.Forty-eight transgenic BLH-SV40 Tag retinoblastoma mice were administered five intravitreal inj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::458ef93a2c7a164ab4fd3905c468e416
https://pubmed.ncbi.nlm.nih.gov/8759359

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Corneal electroretinographic function rescued by normal retinal pigment epithelial grafts in retinal degenerative Royal College of Surgeons rats

Autor: L Q, Jiang, D, Hamasaki

Publikováno v: Investigative ophthalmologyvisual science. 35(13)

This study was designed to examine whether retinal function can be rescued by allogeneic normal retinal pigment epithelial (RPE) grafts in Royal College of Surgeons (RCS) with retinal degeneration and, if so, whether this rescued function can be meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72a4e3c6345e87b5fbc48dece961b54c
https://pubmed.ncbi.nlm.nih.gov/8002250

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