Zobrazeno 1 - 10
of 106
pro vyhledávání: '"D, Gallahan"'
Publikováno v:
Journal of Virology. 69:1932-1938
With a unique mouse mammary tumor model system in which mouse mammary tumor virus (MMTV) insertional mutations can be detected during progression from preneoplasia to frank malignancy, including metastasis, we have discovered a new common integration
Publikováno v:
Journal of Virology. 66:2594-2599
Expression of a 2.3-kb RNA species is induced in mammary tumors as a consequence of insertional mutagenesis at the int-3 locus by the mouse mammary tumor virus. The nucleotide sequence and biological activity of this mammary tumor-specific int-3 RNA
Publikováno v:
Journal of Virology. 65:6365-6370
Nonimmortalized mouse mammary epithelial cells expressing Escherichia coli beta-galactosidase from a murine amphotropic packaged retroviral vector were injected into the epithelium-divested mammary fat pads of syngeneic mice. Mammary glands formed fr
Autor:
L T, Krebs, Y, Xue, C R, Norton, J R, Shutter, M, Maguire, J P, Sundberg, D, Gallahan, V, Closson, J, Kitajewski, R, Callahan, G H, Smith, K L, Stark, T, Gridley
Publikováno v:
Genesdevelopment. 14(11)
The Notch gene family encodes large transmembrane receptors that are components of an evolutionarily conserved intercellular signaling mechanism. To assess the role of the Notch4 gene, we generated Notch4-deficient mice by gene targeting. Embryos hom
Autor:
B A Pancake, Alan E. Williams, A Vallejo, Renu B. Lal, R K Alexander, Charlene S. Dezzutti, Edward Tabor, D Gallahan, Indira Hewlett, Paul R. McCurdy, Elliot P. Cowan, D Zucker-Franklin, K George, George J. Nemo
Publikováno v:
Transfusion. 39(8)
BACKGROUND: It was reported recently that sequences corresponding to the human T-lymphotropic virus type I (HTLV-I) tax gene were detected in peripheral blood mononuclear cells from 8 to 11 percent of healthy blood donors without detectable antibodie
Autor:
S, Kleinman, M P, Busch, L, Hall, R, Thomson, S, Glynn, D, Gallahan, H E, Ownby, A E, Williams
Publikováno v:
JAMA. 280(12)
Persons at risk of human immunodeficiency virus 1 (HIV-1) infection, have been classified incorrectly as HIV infected because of Western blot results, but the frequency of false-positive Western blot results is unknown.To determine the frequency of f
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 206(2)
Functional differentiation of mammary tissue progresses in distinct phases spanning puberty and pregnancy. Here we have analyzed and compared the effects of transforming growth factor beta 1 (TGF beta 1), TGF alpha, and whey acidic protein (WAP), the
Autor:
D, Gallahan, C, Jhappan, G, Robinson, L, Hennighausen, R, Sharp, E, Kordon, R, Callahan, G, Merlino, G H, Smith
Publikováno v:
Cancer research. 56(8)
Insertional mutation of the Int3 gene, a member of the Notch gene family, is frequently associated with primary mouse mammary tumors induced by the mouse mammary tumor virus (MMTV). A major consequence of these mutations is the production of a shorte
Publikováno v:
Journal of virology. 69(12)
In a mouse mammary tumor model system in which carcinogenic progression can be investigated, we have found a unique mutation of Int-3 associated with progression from premalignant lobular hyperplasia to tumor. Sequence analysis of the rearranged frag
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(5)
INT3 is interrupted by retroviral DNA insertion in approximately 18% of primary Czech mouse mammary tumors induced by mouse mammary tumor virus. One consequence of these insertions is the production of a 2.4-kilobase, tumor-specific RNA transcript en