Zobrazeno 1 - 10
of 287
pro vyhledávání: '"D, GOLDRING"'
Publikováno v:
Archives of Microbiology. 205
Autor:
J. D. Goldring, M. Hommel
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 87, Pp 313-322 (1992)
The sequestration of Plasmodium falciparum-infected erythrocytes to the endothelial cells of brain capillaries is believed to represent one of the determining factors in the pathogenesis of cerebral malaria. In vitro studies of cytoadherence provide
Externí odkaz:
https://doaj.org/article/3c4fecebfd7047fdbae3eef9dc6d17dd
Autor:
Mohamad Abdulhai, Liji Raju, Nada Abdul Khalique, Helge B. Larsen, William P. D. Goldring, Emilie Jubeli, Amanda B. Maginty, Michael D. Pungente, David G. Nicholson
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:6364-6378
Previously we reported the synthesis and in vitro evaluation of four novel, short-chain cationic lipid gene delivery vectors, characterized by acyclic or macrocyclic hydrophobic regions composed of, or derived from, two 7-carbon chains. Herein we des
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1445
The delivery of nucleic acids into cells remains an important laboratory cell culture technique and potential clinical therapy, based upon the initial cellular uptake, then translation into protein (in the case of DNA), or gene deletion by RNA interf
Autor:
Emile Jubeli, Nada Abdul Khalique, William P. D. Goldring, David G. Nicholson, Amanda B. Maginty, Helge B. Larsen, Michael D. Pungente, Liji Raju
Publikováno v:
European journal of medicinal chemistry. 125
In this communication we describe the construction of four succinic-based cationic lipids, their formulation with plasmid DNA (pDNA), and an evaluation of their in vitro gene delivery into Chinese hamster ovarian (CHO-K1) cells. The cationic lipids e
Publikováno v:
Methods in Molecular Biology ISBN: 9781493937165
The delivery of nucleic acids into cells remains an important laboratory cell culture technique and potential clinical therapy, based upon the initial cellular uptake, then translation into protein (in the case of DNA), or gene deletion by RNA interf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6776f2c2892c1346c46d89b47a053dd5
https://doi.org/10.1007/978-1-4939-3718-9_2
https://doi.org/10.1007/978-1-4939-3718-9_2
Autor:
Adam J. S. Johnston, Liji Raju, Nada Abdul Khalique, William P. D. Goldring, Deena Wafadari, Michael D. Pungente, Rachael A Downs, Emile Jubeli
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:4686-4692
The synthesis and in vitro evaluation of four cationic lipid gene delivery vectors, characterized by acyclic or macrocyclic, and saturated or unsaturated hydrophobic regions, is described. The synthesis employed standard protocols, including ring-clo
Publikováno v:
Tetrahedron Letters. 52:960-963
Spiro-fused indanones were constructed using a [4 + 2]-cycloaddition approach from α-methylene indanone dienophiles, which were elaborated from 4-chromanone in a number of steps including a key rearrangement process. This type of spiro-fused structu
Publikováno v:
Tetrahedron Letters. 52:859-862
A synthesis of highly substituted and sterically congested bicyclo[4.3.1]decenes, a structure embedded in the core 4,7,6-tricyclic system of natural caryolanes, was successfully achieved via a ring-closing metathesis (RCM) reaction of syn-1,3-diene s
Publikováno v:
Synlett. 2010:547-550
The development of an asymmetric route for the synthesis of α,β-butenolide building blocks, starting from commercially available D -mannitol, is described. The devised route was applied to a synthesis of the (S)-(-)-enantiomer of the antiviral natu