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SI2-SSE: GenApp - A Transformative Generalized Application Cyberinfrastructure

Autor: E H Brookes, J E Curtis, D Fushman, S Krueger, A Savelyev

GenApp, a Generalized Application Framework [https://genapp.rocks], is a framework for rapidly building and deploying applications to an extensible variety of targets including web-based science gateways. GenApp works by building targets from a colle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd181b4409540a27c325293d4bf78a1

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Akademický článek

Osteoblast-Derived ECM1 Promotes Anti-Androgen Resistance in Bone Metastatic Prostate Cancer.

Autor: Wang X; Department of Orthopedic Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, 510080, China., Wang M; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, 510080, China.; Department of Pathology, Guangzhou First People's Hospital, Guangzhou, 510080, China., Lin Q; Department of Orthopedic Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, 510080, China., He L; Department of Experimental Research, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Zhang B; Department of Orthopedic Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, 510080, China., Chen X; Department of Orthopedic Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, 510080, China., Chen G; Department of Orthopedic Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, 510080, China., Du H; Department of Pathology, Guangzhou First People's Hospital, Guangzhou, 510080, China., Lang C; Department of Orthopedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, China., Peng X; Department of Orthopedic Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, 510080, China., Dai Y; Department of Orthopedic Surgery, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.; Guangdong Provincial Key Laboratory of Orthopedics and Traumatology, Guangzhou, 510080, China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov 20, pp. e2407662. Date of Electronic Publication: 2024 Nov 20.

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Akademický článek

Biochemical and Structural Consequences of NEDD8 Acetylation.

Autor: Kienle SM; Departments of Biology and Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstr. 10, 78457, Konstanz, Germany., Schneider T; Departments of Biology and Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstr. 10, 78457, Konstanz, Germany., Bernecker C; Departments of Biology and Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstr. 10, 78457, Konstanz, Germany., Bracker J; Departments of Biology and Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstr. 10, 78457, Konstanz, Germany., Marx A; Departments of Biology and Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstr. 10, 78457, Konstanz, Germany., Kovermann M; Departments of Biology and Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstr. 10, 78457, Konstanz, Germany., Scheffner M; Departments of Biology and Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstr. 10, 78457, Konstanz, Germany., Stuber K; Departments of Biology and Chemistry, Konstanz Research School Chemical Biology, University of Konstanz, Universitätsstr. 10, 78457, Konstanz, Germany.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Nov 18; Vol. 25 (22), pp. e202400478. Date of Electronic Publication: 2024 Sep 23.

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Akademický článek

Exocyclic and Linker Editing of Lys63-linked Ubiquitin Chains Modulators Specifically Inhibits Non-homologous End-joining Repair.

Autor: Saha A; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, 3200008, Israel.; Department of Chemistry, Birla Institute of Technology & Science (BITS) Pilani, Hyderabad Campus, Hyderabad, 500078, Telangana, India., Bishara LA; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Haifa, 3200008, Israel., Saed Y; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, 3200008, Israel., Vamisetti GB; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, 3200008, Israel.; Peptide Drug Research and Development, Combiosz Co. Ltd., Changshu National High-Tech Zone, Suzhou, 215500, China., Mandal S; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, 3200008, Israel., Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, Bunkyo-ku,7-3-1 Hongo, Bunkyo, Tokyo, 113-0033, Japan., Ayoub N; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Haifa, 3200008, Israel., Brik A; Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa, 3200008, Israel.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Oct 24; Vol. 63 (44), pp. e202409012. Date of Electronic Publication: 2024 Sep 24.

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