Zobrazeno 1 - 10
of 1 380
pro vyhledávání: '"D, Fried"'
Autor:
Daniel A. Nissley, Yang Jiang, Fabio Trovato, Ian Sitarik, Karthik B. Narayan, Philip To, Yingzi Xia, Stephen D. Fried, Edward P. O’Brien
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Nissley and co-workers predict protein misfolding into kinetically trapped, entangled conformations that can bypass the proteostasis network to remain soluble but less-functional for long timescales is widespread within the E. coli proteome.
Externí odkaz:
https://doaj.org/article/55213c6dc1714a15a02325661af2e402
Autor:
Stephen D. Fried, Paula J. Booth
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/10a2ad435752493590146513826c77ac
Autor:
Nicholas D. Fried, Joshua M. Oakes, Anna K. Whitehead, Eric Lazartigues, Xinping Yue, Jason D. Gardner
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundThe heart undergoes structural and functional changes in response to injury and hemodynamic stress known as cardiac remodeling. Cardiac remodeling often decompensates causing dysfunction and heart failure (HF). Cardiac remodeling and dysfun
Externí odkaz:
https://doaj.org/article/7cff00d530d54c5c8d2679ad9ca5356b
Publikováno v:
ACS Central Science, Vol 7, Iss 10, Pp 1736-1750 (2021)
Externí odkaz:
https://doaj.org/article/7c66d65ceb324bb6a57afb6497c5cc0b
Autor:
Mikhail Makarov, Alma C. Sanchez Rocha, Robin Krystufek, Ivan Cherepashuk, Volha Dzmitruk, Tatsiana Charnavets, Anneliese M. Faustino, Michal Lebl, Kosuke Fujishima, Stephen D. Fried, Klara Hlouchova
Publikováno v:
Journal of the American Chemical Society. 145:5320-5329
Whereas modern proteins rely on a quasi-universal repertoire of 20 canonical amino acids (AAs), numerous lines of evidence suggest that ancient proteins relied on a limited alphabet of 10 ‘early’ AAs, and that the 10 ‘late’ AAs were products
Autor:
Nicholas J. Galan, Alan D. Fried, Chase E. Cromer, Abigail Fish, Dominic R. Coughlin, Johnathan N. Brantley
Publikováno v:
Journal of Polymer Science.
Akademický článek
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Akademický článek
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Autor:
Anna K. Whitehead, Nicholas D. Fried, Zhen Li, Kandasamy Neelamegam, Charlotte S. Pearson, Kyle B. LaPenna, Thomas E. Sharp, David J. Lefer, Eric Lazartigues, Jason D. Gardner, Xinping Yue
Publikováno v:
Clin Sci (Lond)
Cigarette smoking remains the leading modifiable risk factor for cardiopulmonary diseases; however, the effects of nicotine alone on cardiopulmonary function remain largely unknown. Previously, we have shown that chronic nicotine vapor inhalation in
Publikováno v:
J Am Chem Soc
Evaluating the significance of various forms of DNA damage is complicated by discoveries that some lesions inactivate repair enzymes or produce more deleterious forms of damage. Histone lysines within nucleosomes react with the commonly produced C4