Zobrazeno 1 - 10
of 53
pro vyhledávání: '"D, Durack"'
Autor:
Yukang Lin, John M. Pagel, D. Scott Wilbur, Oliver W. Press, Joseph G. Rajendran, Darrell R. Fisher, Lawrence D. Durack, Ajay K. Gopal, Rune Nilsson, Bengt Sandberg, Eneida R. Nemecek, Damian J. Green
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 23:181-191
Radiolabeled anti-CD20 antibodies have demonstrated impressive efficacy in the treatment of relapsed non-Hodgkin's lymphoma. However, the amount of radiation that can be delivered to eradicate the malignancy is limited by toxicity to normal organs. W
Autor:
Irwin D. Bernstein, Oliver W. Press, Frederick R. Appelbaum, David G. Maloney, Joseph G. Rajendran, Paul J. Martin, Janet F. Eary, Lawrence D. Durack, Dana C. Matthews, Stephen H. Petersdorf, Jane Golden, Ajay K. Gopal, Sharon A. Bush, Ted Gooley
Publikováno v:
Blood. 102:2351-2357
We performed a multivariable comparison of 125 consecutive patients with follicular lymphoma (FL) treated at our centers with either high-dose radioimmunotherapy (HD-RIT) using 131I-anti-CD20 (n = 27) or conventional high-dose therapy (C-HDT) (n = 98
Autor:
Rainer Storb, M. John Gass, George E. Georges, Barry E. Storer, Wil B. Nelp, Kraig Abrams, Sean P. McDonough, Murad Y. Yunusov, Sherrill J. Slichter, Richard A. Nash, Lawrence D. Durack, Samuel A. Burstein, Peter F Moore
Publikováno v:
British Journal of Haematology. 121:614-622
To characterize recombinant human macrophage-colony stimulating factor (rhM-CSF)-associated thrombocytopenia (TCP), in vivo studies were performed in dogs, including the biodistributions and recoveries of radiolabelled autologous and allogeneic plate
Autor:
Darrell R. Fisher, Janet F. Eary, Sharon A. Bush, Stephen Liu, Frederick R. Appelbaum, Irwin D. Bernstein, Oliver W. Press, Ajay K. Gopal, Justin P. Smith, James W. Borrow, David G. Maloney, Stephen H. Petersdorf, Dana C. Matthews, Paul J. Martin, Ted Gooley, Bruce A. Porter, Brent L. Wood, Lawrence D. Durack, Joseph G. Rajendran
Publikováno v:
Blood. 96:2934-2942
Relapsed B-cell lymphomas are incurable with conventional chemotherapy and radiation therapy, although a fraction of patients can be cured with high-dose chemoradiotherapy and autologous stem-cell transplantation (ASCT). We conducted a phase I/II tri
Autor:
Frederick R. Appelbaum, David A. Mitchell, Paul J. Martin, Lawrence D. Durack, T. Edmond Hui, Irwin D. Bernstein, Darrell R. Fisher, Rainer Storb, Janet F. Eary, Oliver W. Press, Dana C. Matthews
Publikováno v:
Blood. 94:1237-1247
Delivery of targeted hematopoietic irradiation using radiolabeled monoclonal antibody may improve the outcome of marrow transplantation for advanced acute leukemia by decreasing relapse without increasing toxicity. We conducted a phase I study that e
Autor:
Dana C. Matthews, Frederick R. Appelbaum, Janet F. Eary, Darrell R. Fisher, Lawrence D. Durack, T. Edmond Hui, Paul J. Martin, David Mitchell, Oliver W. Press, Rainer Storb, Irwin D. Bernstein
Publikováno v:
Blood. 94:1237-1247
Delivery of targeted hematopoietic irradiation using radiolabeled monoclonal antibody may improve the outcome of marrow transplantation for advanced acute leukemia by decreasing relapse without increasing toxicity. We conducted a phase I study that e
Publikováno v:
Nuclear Medicine and Biology. 24:635-638
Non-Hodgkin's lymphoma I-131 radioimmunotherapy data were analyzed to determine whether a predictive relationship exists between radiation absorbed doses calculated from biodistribution studies and doses derived from patient size. Radioactivity treat
Autor:
Lawrence D. Durack, FR Appelbaum, Kraig Abrams, W Yang, Richard A. Nash, H. J. Deeg, Rainer Storb, Tom Boone, Friedrich Schuening, S. A. Burstein
Publikováno v:
Blood. 86:1765-1775
Administration of recombinant canine granulocyte-macrophage colony- stimulating factor (rcGM-CSF) to normal dogs in previous studies induced an increase in peripheral blood neutrophils and a dose- dependent decrease in platelet counts. In six dogs th
Autor:
Lawrence D. Durack, Oliver W. Press, T E Hui, David A. Mitchell, D R Fisher, Dana C. Matthews, Janet F. Eary, P.J. Martin, Sharon A. Bush, FR Appelbaum
Publikováno v:
Blood. 85:1122-1131
In an attempt to decrease the relapse rate after bone marrow transplantation (BMT) for advanced acute leukemia, we initiated studies using 131I-labeled anti-CD45 antibody (BC8) to deliver radiation specifically to hematopoietic tissues, followed by a
Autor:
Te Hui, Dana C. Matthews, P.J. Martin, Fisher, Janet F. Eary, Christopher C. Badger, W. B. Nelp, Oliver W. Press, FR Appelbaum, Lawrence D. Durack
Publikováno v:
Blood. 78:1864-1874
Despite bone marrow transplantation, many patients with advanced leukemia subsequently relapse. If an additional increment of radiation could be delivered to lymphohematopoietic tissues with relative specificity, the relapse rate may decrease without